RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 15.891
EU - Europa 6.928
AS - Asia 3.195
SA - Sud America 232
AF - Africa 28
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 9
Totale 26.298
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Nazione #
US - Stati Uniti d'America 15.831
GB - Regno Unito 2.493
SG - Singapore 1.376
IT - Italia 1.187
SE - Svezia 936
DE - Germania 713
CN - Cina 702
HK - Hong Kong 584
RU - Federazione Russa 383
UA - Ucraina 356
FI - Finlandia 246
BR - Brasile 201
TR - Turchia 197
BG - Bulgaria 159
FR - Francia 115
ID - Indonesia 101
NL - Olanda 65
BE - Belgio 57
IE - Irlanda 51
CA - Canada 50
IN - India 48
LT - Lituania 42
BD - Bangladesh 40
VN - Vietnam 26
ES - Italia 20
JP - Giappone 20
IR - Iran 14
PL - Polonia 14
AU - Australia 13
CH - Svizzera 13
KR - Corea 13
AT - Austria 11
CL - Cile 11
AR - Argentina 10
EG - Egitto 10
RO - Romania 9
IL - Israele 8
PK - Pakistan 8
EU - Europa 7
HU - Ungheria 7
UZ - Uzbekistan 7
ZA - Sudafrica 7
AE - Emirati Arabi Uniti 6
GR - Grecia 6
HR - Croazia 6
LK - Sri Lanka 6
NG - Nigeria 6
SA - Arabia Saudita 6
BY - Bielorussia 5
KZ - Kazakistan 5
MY - Malesia 5
EC - Ecuador 4
NO - Norvegia 4
PT - Portogallo 4
AL - Albania 3
AZ - Azerbaigian 3
CO - Colombia 3
CY - Cipro 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
DZ - Algeria 3
LA - Repubblica Popolare Democratica del Laos 3
LU - Lussemburgo 3
LV - Lettonia 3
MX - Messico 3
PH - Filippine 3
RS - Serbia 3
BZ - Belize 2
EE - Estonia 2
IQ - Iraq 2
JO - Giordania 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BH - Bahrain 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
GE - Georgia 1
GT - Guatemala 1
LB - Libano 1
MA - Marocco 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PS - Palestinian Territory 1
PY - Paraguay 1
TH - Thailandia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 26.298
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Città #
Fairfield 2.309
Santa Clara 1.806
Southend 1.720
Woodbridge 1.291
Ashburn 1.192
Chandler 1.007
Houston 1.001
Seattle 906
Cambridge 801
Jacksonville 746
Wilmington 723
Ann Arbor 603
Dearborn 577
Hong Kong 576
Nyköping 572
Singapore 571
London 472
Modena 229
Beijing 192
San Diego 183
Council Bluffs 172
Princeton 169
Sofia 157
Eugene 135
Milan 124
Helsinki 123
Izmir 114
Munich 111
Des Moines 101
Bologna 95
Jakarta 92
New York 89
Moscow 74
Brussels 56
Dublin 47
Frankfurt am Main 44
Shanghai 44
Bremen 38
Redwood City 38
Rome 36
Falls Church 34
Boardman 32
Los Angeles 32
Reggio Emilia 28
Hefei 27
Guangzhou 26
Parma 26
Toronto 26
Norwalk 25
Saint Petersburg 22
São Paulo 21
Chicago 20
Kilburn 19
Nanjing 19
Dong Ket 18
Kunming 18
Amsterdam 16
Fremont 15
Hounslow 15
Jinan 14
Nuremberg 14
Washington 14
Formigine 13
Grafing 13
Phoenix 12
Chiswick 11
Milwaukee 11
Ottawa 11
Paris 11
Verona 11
Dallas 10
Fuzhou 10
San Francisco 10
Siena 10
Frattamaggiore 9
Vienna 9
Bari 8
Brescia 8
Indiana 8
Meana Sardo 8
Nanchang 8
Serra 8
Wandsworth 8
Auburn Hills 7
Bergamo 7
Chengdu 7
Edinburgh 7
Naples 7
Philadelphia 7
Porto Mantovano 7
Renton 7
Shenzhen 7
Tokyo 7
Turin 7
Wuhan 7
Zhengzhou 7
Zurich 7
Boston 6
Cairo 6
Colombo 6
Totale 20.140
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 483
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 320
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 303
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 288
BEAR, a Molecular Docking Refinement and Rescoring Method 287
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 243
Selection of protein conformations for structure-based polypharmacology studies 242
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 241
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 238
Role of bifidobacteria in the hydrolysis of chlorogenic acid 235
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 232
On the integration of in silico drug design methods for drug repurposing 231
BEAR, a novel virtual screening methodology for drug discovery 230
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 229
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 224
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 222
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 222
Polypharmacology: challenges and opportunities in drug discovery 221
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 219
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 217
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 216
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 215
Advances and applications of binding affinity prediction methods in drug discovery 215
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 214
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 214
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 212
A rational approach to the design of flavones as xanthine oxidase inhibitors 211
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 211
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 208
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 205
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 205
A computational workflow for the design of irreversible inhibitors of protein kinases. 204
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 203
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 202
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 202
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 201
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 199
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 196
A model of the interaction of substrates and inhibitors with xanthine oxidase 193
Histone deacetylases: Structural determinants of inhibitor selectivity 193
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 192
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 192
Structural bases for the inhibition of aldose reductase by phenolic compounds 190
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 190
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 190
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 189
αC helix displacement as a general approach for allosteric modulation of protein kinases 189
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 189
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 189
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 188
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 186
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 185
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 184
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 184
Computational polypharmacology analysis of the heat shock protein 90 interactome 183
Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor Tolrestat 183
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 183
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 183
Virtual screening on large scale grids 182
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 182
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 182
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 182
Exploring the binding site of C-terminal Hsp90 inhibitors 181
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 181
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 181
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 181
Solvent effects on the tautomerism of apigeninidin 180
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 178
Structure-based design of 7-carbamate analogs of geldanamycin 178
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 178
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 177
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 177
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 177
Molecular docking: Shifting paradigms in drug discovery 177
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 176
Pharmacological approaches to the treatment of diabetic complications 175
G48A, a new KRAS mutation found in lung adenocarcinoma 175
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 175
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 174
Grid-enabled high throughput virtual screening 174
Nitrophenyl derivatives as Aldose Reductase inhibitors 174
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 173
Computational polypharmacology comes of age 173
Dimerization hot spots in the structure of human Hsp90 172
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 172
Targeting the Hsp90 interactome using in silico polypharmacology approaches 172
Synthesis and Biological Evaluation of Migrastatin Macrotriazoles 167
Free energy perturbation studies on binding of the inhibitor 5,6-dihydrobenzo[h]cinnolin-3(2H)one-2-acetic acid and its methoxylated analogs to aldose reductase 165
Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds 165
Binding estimation after refinement: BEARing out an innovative virtual screening methodology 165
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 165
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 164
Dual Kinase-Bromodomain Inhibitors in Anticancer Drug Discovery: A Structural and Pharmacological Perspective 164
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 162
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 161
Docking and database screening reveal new classes of Plasmodium falciparum dihydrofolate reductase inhibitors 160
Structure-based and in silico design of Hsp90 inhibitors 158
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 157
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 155
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 153
Totale 19.835
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Categoria #
all - tutte 109.671
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 109.671
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020675 0 0 0 0 0 0 0 0 0 196 249 230
2020/20213.939 411 236 273 367 354 287 331 457 245 500 249 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.985 400 373 215 232 323 437 79 270 408 50 141 57
2023/20241.898 64 122 130 160 432 150 166 314 36 41 80 203
2024/20255.594 258 66 122 508 1.314 969 369 633 697 658 0 0
Totale 26.623