RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 20.764
AS - Asia 9.649
EU - Europa 8.867
SA - Sud America 1.485
AF - Africa 212
OC - Oceania 52
Continente sconosciuto - Info sul continente non disponibili 10
Totale 41.039
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Nazione #
US - Stati Uniti d'America 20.426
SG - Singapore 2.994
GB - Regno Unito 2.608
CN - Cina 2.556
IT - Italia 1.584
BR - Brasile 1.151
HK - Hong Kong 1.149
VN - Vietnam 1.116
SE - Svezia 978
DE - Germania 935
FI - Finlandia 512
RU - Federazione Russa 429
BD - Bangladesh 392
UA - Ucraina 392
PL - Polonia 365
FR - Francia 295
TR - Turchia 266
KR - Corea 258
IN - India 220
ID - Indonesia 170
BG - Bulgaria 165
CA - Canada 159
NL - Olanda 141
AR - Argentina 121
MX - Messico 103
ES - Italia 94
JP - Giappone 77
IQ - Iraq 71
BE - Belgio 67
IE - Irlanda 59
ZA - Sudafrica 54
PK - Pakistan 53
AU - Australia 48
EC - Ecuador 48
LT - Lituania 48
CO - Colombia 43
AE - Emirati Arabi Uniti 41
AT - Austria 38
VE - Venezuela 36
CL - Cile 34
UZ - Uzbekistan 34
MA - Marocco 33
SA - Arabia Saudita 27
EG - Egitto 25
PH - Filippine 24
KE - Kenya 21
CH - Svizzera 20
IR - Iran 20
JO - Giordania 20
RO - Romania 20
MY - Malesia 17
UY - Uruguay 17
AZ - Azerbaigian 16
TN - Tunisia 16
DO - Repubblica Dominicana 15
PY - Paraguay 15
TH - Thailandia 14
IL - Israele 13
KZ - Kazakistan 13
NP - Nepal 13
DZ - Algeria 12
PT - Portogallo 12
HU - Ungheria 11
AL - Albania 10
RS - Serbia 10
BY - Bielorussia 9
CI - Costa d'Avorio 9
CR - Costa Rica 9
HN - Honduras 9
HR - Croazia 9
NG - Nigeria 9
NO - Norvegia 9
PE - Perù 9
PR - Porto Rico 9
TW - Taiwan 9
BO - Bolivia 8
GR - Grecia 8
KH - Cambogia 8
LK - Sri Lanka 8
OM - Oman 8
SK - Slovacchia (Repubblica Slovacca) 8
SN - Senegal 8
ET - Etiopia 7
EU - Europa 7
CZ - Repubblica Ceca 6
LB - Libano 6
PA - Panama 6
AO - Angola 5
BH - Bahrain 5
CY - Cipro 5
JM - Giamaica 5
NI - Nicaragua 5
QA - Qatar 5
TT - Trinidad e Tobago 5
DK - Danimarca 4
GT - Guatemala 4
SI - Slovenia 4
BA - Bosnia-Erzegovina 3
BB - Barbados 3
GE - Georgia 3
Totale 40.978
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Città #
Fairfield 2.310
Ashburn 2.004
Santa Clara 1.911
Southend 1.720
Singapore 1.597
Woodbridge 1.292
Hong Kong 1.120
Houston 1.018
Chandler 1.007
Seattle 914
Hefei 867
Cambridge 802
Jacksonville 751
Wilmington 741
San Jose 623
Ann Arbor 603
Dearborn 577
Nyköping 572
London 489
Council Bluffs 468
Beijing 456
Helsinki 364
Ho Chi Minh City 359
Warsaw 349
Hanoi 275
Los Angeles 275
Modena 246
Seoul 240
The Dalles 225
Chicago 202
New York 196
Milan 195
San Diego 190
Dallas 177
Princeton 169
Sofia 158
Munich 143
Eugene 135
Lauterbourg 123
Berlin 118
Izmir 116
Jakarta 114
Des Moines 102
São Paulo 95
Shanghai 94
Buffalo 93
Bologna 92
Frankfurt am Main 86
Salt Lake City 84
Moscow 81
Orem 73
Tokyo 61
Brussels 58
Rome 57
Dublin 54
Boardman 47
Mexico City 46
Phoenix 44
Porto Alegre 44
Columbus 43
Da Nang 42
Toronto 42
Guangzhou 40
Haiphong 40
Tampa 40
Amsterdam 39
Redwood City 39
Bremen 38
Elk Grove Village 37
Reggio Emilia 37
Atlanta 36
Chennai 36
Falls Church 34
Kent 34
Rio de Janeiro 33
Groningen 32
Denver 30
Miano 30
Tashkent 29
Parma 28
Baghdad 27
Nuremberg 27
Biên Hòa 26
Brooklyn 26
Paris 26
Johannesburg 25
Montreal 25
Norwalk 25
Belo Horizonte 23
Nanjing 23
Redondo Beach 23
San Francisco 23
Boston 22
Canberra 22
Hải Dương 22
Saint Petersburg 22
Yalova 22
Barcelona 21
Dhaka 21
Naples 21
Totale 28.653
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 1.297
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 476
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 432
Polypharmacology: challenges and opportunities in drug discovery 429
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 427
BEAR, a Molecular Docking Refinement and Rescoring Method 381
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 374
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 372
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 371
A rational approach to the design of flavones as xanthine oxidase inhibitors 366
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 360
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 351
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 346
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 338
A model of the interaction of substrates and inhibitors with xanthine oxidase 335
Role of bifidobacteria in the hydrolysis of chlorogenic acid 333
A computational workflow for the design of irreversible inhibitors of protein kinases 331
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 328
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 326
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 324
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 323
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 323
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 322
Advances and applications of binding affinity prediction methods in drug discovery 322
BEAR, a novel virtual screening methodology for drug discovery 315
On the integration of in silico drug design methods for drug repurposing 313
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 313
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 312
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 309
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 309
Selection of protein conformations for structure-based polypharmacology studies 309
Molecular docking: Shifting paradigms in drug discovery 306
Grid-enabled high throughput virtual screening 305
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 305
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 305
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 301
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 299
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 296
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 292
Virtual screening on large scale grids 287
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 285
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 283
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 283
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 282
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 282
Identification of Target Associations for Polypharmacology from Analysis of Crystallographic Ligands of the Protein Data Bank 282
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 281
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 281
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 281
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 280
Structural bases for the inhibition of aldose reductase by phenolic compounds 279
Fast and accurate predictions of relative binding free energies using MM-PBSA and MM-GBSA 275
αC helix displacement as a general approach for allosteric modulation of protein kinases 272
Exploring the binding site of C-terminal Hsp90 inhibitors 271
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 271
Nitrophenyl derivatives as Aldose Reductase inhibitors 270
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 270
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 269
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 269
Computational polypharmacology analysis of the heat shock protein 90 interactome 268
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 268
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 265
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 264
Pharmacological approaches to the treatment of diabetic complications 263
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 263
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 261
ANTHOCYANIDINES AS INHIBITORS OF XANTHINE-OXIDASE 261
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 260
Design and discovery of plasmepsin inhibitors using an automated workflow on large scale grids 259
Histone deacetylases: Structural determinants of inhibitor selectivity 259
Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models 259
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 256
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 255
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 254
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 252
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 251
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 250
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 249
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 249
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 248
Solvent effects on the tautomerism of apigeninidin 247
Activité Antilipoperoxydante d'Extraits Polyphenoliques de Ribes Nigrum L. 247
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 247
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity contants of variously hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition 246
Structure-based design of 7-carbamate analogs of geldanamycin 245
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 245
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 241
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 240
Computational polypharmacology comes of age 238
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 237
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 236
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 235
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 234
Targeting the Hsp90 interactome using in silico polypharmacology approaches 234
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 233
Structure-based and in silico design of Hsp90 inhibitors 230
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 230
LigAdvisor: A versatile and user-friendly web-platform for drug design 229
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 227
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 226
Totale 29.890
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Categoria #
all - tutte 153.616
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 153.616
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021229 0 0 0 0 0 0 0 0 0 0 0 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.980 400 373 215 232 323 437 79 270 408 48 138 57
2023/20241.877 63 122 128 154 432 144 162 314 36 41 79 202
2024/20257.356 257 66 121 505 1.306 964 351 619 680 808 774 905
2025/202613.008 793 660 1.205 1.486 1.524 1.188 1.410 640 1.269 1.297 921 615
Totale 41.367