RASTELLI, Giulio
 Distribuzione geografica
Continente #
NA - Nord America 13.635
EU - Europa 5.595
AS - Asia 1.287
SA - Sud America 25
AF - Africa 19
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 7
Totale 20.576
Nazione #
US - Stati Uniti d'America 13.593
GB - Regno Unito 2.073
IT - Italia 920
SE - Svezia 891
DE - Germania 584
CN - Cina 486
HK - Hong Kong 382
UA - Ucraina 352
FI - Finlandia 199
TR - Turchia 188
BG - Bulgaria 157
FR - Francia 102
RU - Federazione Russa 78
ID - Indonesia 52
BE - Belgio 51
IE - Irlanda 46
IN - India 44
CA - Canada 37
LT - Lituania 36
BD - Bangladesh 34
VN - Vietnam 23
JP - Giappone 20
NL - Olanda 18
ES - Italia 17
IR - Iran 14
PL - Polonia 13
BR - Brasile 12
CH - Svizzera 10
CL - Cile 10
SG - Singapore 10
KR - Corea 9
RO - Romania 8
AU - Australia 7
EG - Egitto 7
EU - Europa 7
GR - Grecia 6
HR - Croazia 6
AT - Austria 5
IL - Israele 5
MY - Malesia 5
NG - Nigeria 5
ZA - Sudafrica 5
HU - Ungheria 4
SA - Arabia Saudita 4
CZ - Repubblica Ceca 3
NO - Norvegia 3
RS - Serbia 3
BY - Bielorussia 2
BZ - Belize 2
CO - Colombia 2
LK - Sri Lanka 2
PH - Filippine 2
PR - Porto Rico 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DZ - Algeria 1
EC - Ecuador 1
GE - Georgia 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LV - Lettonia 1
MD - Moldavia 1
MX - Messico 1
OM - Oman 1
PK - Pakistan 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 20.576
Città #
Fairfield 2.309
Southend 1.720
Woodbridge 1.291
Ashburn 1.175
Chandler 1.007
Houston 1.001
Seattle 904
Cambridge 799
Jacksonville 746
Wilmington 723
Ann Arbor 603
Dearborn 577
Nyköping 572
Hong Kong 376
Modena 210
Beijing 183
San Diego 183
Princeton 169
Sofia 155
Eugene 135
Izmir 114
Des Moines 101
Milan 95
New York 89
Helsinki 84
London 71
Bologna 63
Brussels 50
Jakarta 44
Dublin 42
Bremen 38
Redwood City 38
Frankfurt am Main 36
Falls Church 34
Rome 32
Boardman 31
Shanghai 27
Hefei 26
Norwalk 25
Saint Petersburg 22
Toronto 21
Kilburn 19
Dong Ket 18
Kunming 18
Nanjing 18
Fremont 15
Hounslow 15
Munich 15
Parma 14
Grafing 13
Washington 13
Phoenix 12
Chiswick 11
Milwaukee 11
Verona 11
Guangzhou 10
Jinan 10
Frattamaggiore 9
Los Angeles 9
San Francisco 9
Chicago 8
Indiana 8
Meana Sardo 8
Nanchang 8
Paris 8
Serra 8
Siena 8
Wandsworth 8
Auburn Hills 7
Brescia 7
Edinburgh 7
Philadelphia 7
Porto Mantovano 7
Renton 7
Tokyo 7
Turin 7
Chengdu 6
Florence 6
San Cesario sul Panaro 6
Shenzhen 6
Trieste 6
West Jordan 6
Boston 5
Caorso 5
Carpi 5
Fuzhou 5
Orzinuovi 5
Piacenza 5
Portici 5
San Mateo 5
Santa Cruz De Tenerife 5
Segrate 5
Southwark 5
Warsaw 5
Acton 4
Andover 4
Bari 4
Basingstoke 4
Frosinone 4
Garbagnate Milanese 4
Totale 16.411
Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 343
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 256
BEAR, a Molecular Docking Refinement and Rescoring Method 244
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 237
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 209
Selection of protein conformations for structure-based polypharmacology studies 207
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 205
Role of bifidobacteria in the hydrolysis of chlorogenic acid 204
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 197
On the integration of in silico drug design methods for drug repurposing 196
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 195
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 195
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 194
BEAR, a novel virtual screening methodology for drug discovery 194
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 191
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 189
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 184
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 184
Polypharmacology: challenges and opportunities in drug discovery 184
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 182
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 180
Advances and applications of binding affinity prediction methods in drug discovery 177
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 177
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 177
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 176
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 175
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 175
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 175
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 173
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 171
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 171
A computational workflow for the design of irreversible inhibitors of protein kinases. 170
A rational approach to the design of flavones as xanthine oxidase inhibitors 167
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 167
Histone deacetylases: Structural determinants of inhibitor selectivity 166
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 166
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 165
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 164
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 163
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 162
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 162
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 160
Structural bases for the inhibition of aldose reductase by phenolic compounds 159
Exploring the binding site of C-terminal Hsp90 inhibitors 159
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 159
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 158
αC helix displacement as a general approach for allosteric modulation of protein kinases 158
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 158
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 158
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 157
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 157
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 156
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 156
Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor Tolrestat 155
Solvent effects on the tautomerism of apigeninidin 153
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 152
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 152
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 152
Computational polypharmacology analysis of the heat shock protein 90 interactome 152
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 152
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 152
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 152
A model of the interaction of substrates and inhibitors with xanthine oxidase 150
Pharmacological approaches to the treatment of diabetic complications 150
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 149
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 148
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 148
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 147
Computational polypharmacology comes of age 146
Structure-based design of 7-carbamate analogs of geldanamycin 145
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 145
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 145
G48A, a new KRAS mutation found in lung adenocarcinoma 144
Nitrophenyl derivatives as Aldose Reductase inhibitors 143
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 142
Grid-enabled high throughput virtual screening 142
Dimerization hot spots in the structure of human Hsp90 142
Synthesis and Biological Evaluation of Migrastatin Macrotriazoles 142
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 142
Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds 142
Binding estimation after refinement: BEARing out an innovative virtual screening methodology 142
Virtual screening on large scale grids 141
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 140
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 140
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 140
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 140
Targeting the Hsp90 interactome using in silico polypharmacology approaches 140
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 138
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 137
Free energy perturbation studies on binding of the inhibitor 5,6-dihydrobenzo[h]cinnolin-3(2H)one-2-acetic acid and its methoxylated analogs to aldose reductase 137
Structure-based and in silico design of Hsp90 inhibitors 133
Dual Kinase-Bromodomain Inhibitors in Anticancer Drug Discovery: A Structural and Pharmacological Perspective 133
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 131
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 127
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 125
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 124
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 124
Exploiting computationally derived out-of-the-box protein conformations for drug design 124
Emerging Topics in Structure-Based Virtual Screening 122
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 121
Totale 16.307
Categoria #
all - tutte 82.175
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 82.175


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019463 0 0 0 0 0 0 0 0 0 0 0 463
2019/20205.270 386 169 229 431 633 749 826 629 543 196 249 230
2020/20213.939 411 236 273 367 354 287 331 457 245 500 249 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.985 400 373 215 232 323 437 79 270 408 50 141 57
2023/20241.759 64 122 130 160 432 150 166 314 36 41 80 64
Totale 20.890