RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 21.722
AS - Asia 9.736
EU - Europa 8.922
SA - Sud America 1.495
Continente sconosciuto - Info sul continente non disponibili 340
AF - Africa 222
OC - Oceania 58
Totale 42.495
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Nazione #
US - Stati Uniti d'America 21.327
SG - Singapore 3.001
CN - Cina 2.567
GB - Regno Unito 2.560
IT - Italia 1.709
HK - Hong Kong 1.158
BR - Brasile 1.156
VN - Vietnam 1.098
SE - Svezia 973
DE - Germania 932
FI - Finlandia 504
BD - Bangladesh 450
RU - Federazione Russa 421
UA - Ucraina 386
PL - Polonia 365
FR - Francia 293
TR - Turchia 265
KR - Corea 259
IN - India 230
CA - Canada 180
ID - Indonesia 173
BG - Bulgaria 163
NL - Olanda 146
AR - Argentina 120
MX - Messico 103
ES - Italia 96
JP - Giappone 78
IQ - Iraq 71
BE - Belgio 67
IE - Irlanda 59
ZA - Sudafrica 55
AU - Australia 54
PK - Pakistan 52
EC - Ecuador 48
LT - Lituania 48
CO - Colombia 47
AE - Emirati Arabi Uniti 41
AT - Austria 39
VE - Venezuela 37
CL - Cile 34
UZ - Uzbekistan 34
MA - Marocco 33
EG - Egitto 28
SA - Arabia Saudita 27
IR - Iran 25
PH - Filippine 24
RO - Romania 22
KE - Kenya 21
CH - Svizzera 20
CR - Costa Rica 20
JO - Giordania 20
MY - Malesia 20
TN - Tunisia 17
UY - Uruguay 17
AZ - Azerbaigian 16
DO - Repubblica Dominicana 15
PY - Paraguay 15
TH - Thailandia 14
DZ - Algeria 13
KZ - Kazakistan 13
NP - Nepal 13
HN - Honduras 12
IL - Israele 12
PR - Porto Rico 12
PT - Portogallo 12
HU - Ungheria 11
AL - Albania 10
CI - Costa d'Avorio 10
GT - Guatemala 10
JM - Giamaica 10
RS - Serbia 10
BO - Bolivia 9
BY - Bielorussia 9
HR - Croazia 9
NG - Nigeria 9
NO - Norvegia 9
PE - Perù 9
SK - Slovacchia (Repubblica Slovacca) 9
TT - Trinidad e Tobago 9
TW - Taiwan 9
GR - Grecia 8
KH - Cambogia 8
LK - Sri Lanka 8
OM - Oman 8
SN - Senegal 8
CZ - Repubblica Ceca 7
ET - Etiopia 7
EU - Europa 7
AO - Angola 6
LB - Libano 6
NI - Nicaragua 6
PA - Panama 6
BH - Bahrain 5
CY - Cipro 5
QA - Qatar 5
BB - Barbados 4
DK - Danimarca 4
SC - Seychelles 4
SI - Slovenia 4
BA - Bosnia-Erzegovina 3
Totale 42.101
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Città #
Fairfield 2.304
Ashburn 2.258
Santa Clara 1.939
Southend 1.675
Singapore 1.606
Woodbridge 1.292
Hong Kong 1.127
Houston 1.027
Chandler 996
Seattle 915
Hefei 865
Cambridge 800
Wilmington 740
Jacksonville 734
San Jose 717
Council Bluffs 679
Ann Arbor 602
Nyköping 567
Dearborn 557
London 485
Beijing 460
Helsinki 359
Ho Chi Minh City 350
Warsaw 349
Los Angeles 294
Hanoi 265
Modena 254
Seoul 238
The Dalles 224
Milan 215
Chicago 213
New York 208
San Diego 190
Dallas 185
Princeton 164
Sofia 155
Munich 143
Eugene 132
Lauterbourg 121
Berlin 118
Izmir 115
Jakarta 114
Des Moines 102
Bologna 101
Buffalo 99
Shanghai 94
São Paulo 94
Frankfurt am Main 85
Salt Lake City 84
Moscow 78
Orem 71
Columbus 70
Rome 62
Tokyo 62
Brussels 58
Dublin 54
Boardman 53
Phoenix 50
Mexico City 47
Toronto 46
Porto Alegre 44
Da Nang 42
Reggio Emilia 41
Tampa 41
Amsterdam 40
Chennai 40
Guangzhou 40
Haiphong 40
Atlanta 39
Redwood City 39
Bremen 38
Elk Grove Village 38
Kent 35
Falls Church 34
Rio de Janeiro 33
Groningen 32
Denver 30
Miano 30
Brooklyn 29
Parma 29
Tashkent 29
Naples 28
Baghdad 27
Nuremberg 27
Biên Hòa 26
Norwalk 26
Paris 26
Johannesburg 25
Montreal 25
North Charleston 25
San Francisco 25
Boston 24
Belo Horizonte 23
Washington 23
Canberra 22
Hải Dương 22
Nanjing 22
Redondo Beach 22
Yalova 22
Barcelona 21
Totale 29.285
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 1.336
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 482
Polypharmacology: challenges and opportunities in drug discovery 482
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 439
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 437
BEAR, a Molecular Docking Refinement and Rescoring Method 387
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 385
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 383
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 380
A rational approach to the design of flavones as xanthine oxidase inhibitors 376
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 370
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 367
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 349
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 349
Role of bifidobacteria in the hydrolysis of chlorogenic acid 342
A model of the interaction of substrates and inhibitors with xanthine oxidase 340
Molecular docking: Shifting paradigms in drug discovery 338
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 337
A computational workflow for the design of irreversible inhibitors of protein kinases 335
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 334
Advances and applications of binding affinity prediction methods in drug discovery 334
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 333
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 329
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 328
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 327
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 324
On the integration of in silico drug design methods for drug repurposing 324
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 321
Grid-enabled high throughput virtual screening 319
BEAR, a novel virtual screening methodology for drug discovery 318
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 316
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 313
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 313
Selection of protein conformations for structure-based polypharmacology studies 313
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 313
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 313
Fast and accurate predictions of relative binding free energies using MM-PBSA and MM-GBSA 310
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 308
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 305
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 298
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 296
Virtual screening on large scale grids 294
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 292
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 292
Identification of Target Associations for Polypharmacology from Analysis of Crystallographic Ligands of the Protein Data Bank 290
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 289
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 289
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 289
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 289
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 288
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 287
Structural bases for the inhibition of aldose reductase by phenolic compounds 283
αC helix displacement as a general approach for allosteric modulation of protein kinases 280
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 278
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 276
Exploring the binding site of C-terminal Hsp90 inhibitors 276
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 276
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 275
Nitrophenyl derivatives as Aldose Reductase inhibitors 275
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 274
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 273
Computational polypharmacology analysis of the heat shock protein 90 interactome 273
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 273
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 271
Pharmacological approaches to the treatment of diabetic complications 270
Histone deacetylases: Structural determinants of inhibitor selectivity 270
Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models 268
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 267
ANTHOCYANIDINES AS INHIBITORS OF XANTHINE-OXIDASE 266
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 266
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 265
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 264
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 262
Design and discovery of plasmepsin inhibitors using an automated workflow on large scale grids 262
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 262
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 262
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 261
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 260
Structure-based design of 7-carbamate analogs of geldanamycin 255
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 255
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity contants of variously hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition 254
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 254
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 253
Activité Antilipoperoxydante d'Extraits Polyphenoliques de Ribes Nigrum L. 252
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 252
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 250
Targeting the Hsp90 interactome using in silico polypharmacology approaches 250
Solvent effects on the tautomerism of apigeninidin 248
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 247
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 247
Computational polypharmacology comes of age 245
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 241
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 240
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 240
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 240
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 237
LigAdvisor: A versatile and user-friendly web-platform for drug design 236
Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor Tolrestat 234
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 233
Structure-based and in silico design of Hsp90 inhibitors 233
Totale 30.786
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Categoria #
all - tutte 160.377
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 160.377
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.535 0 0 377 164 72 146 209 167 296 254 527 323
2022/20232.952 396 372 215 229 317 435 79 267 399 48 138 57
2023/20241.863 62 121 126 154 427 144 159 314 36 41 79 200
2024/20257.333 254 66 120 499 1.288 953 367 627 683 800 775 901
2025/202613.033 806 665 1.210 1.486 1.525 1.187 1.385 644 1.268 1.291 928 638
2026/20271.311 458 823 30 0 0 0 0 0 0 0 0 0
Totale 42.495