RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 18.701
EU - Europa 8.020
AS - Asia 7.403
SA - Sud America 1.175
AF - Africa 129
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 10
Totale 35.462
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Nazione #
US - Stati Uniti d'America 18.509
GB - Regno Unito 2.574
SG - Singapore 2.548
CN - Cina 2.323
IT - Italia 1.324
HK - Hong Kong 1.022
SE - Svezia 977
BR - Brasile 970
DE - Germania 784
VN - Vietnam 463
RU - Federazione Russa 419
FI - Finlandia 383
UA - Ucraina 381
PL - Polonia 360
TR - Turchia 238
KR - Corea 206
BG - Bulgaria 163
FR - Francia 142
ID - Indonesia 140
IN - India 127
NL - Olanda 123
CA - Canada 95
AR - Argentina 88
BD - Bangladesh 81
ES - Italia 76
MX - Messico 61
BE - Belgio 60
JP - Giappone 57
IE - Irlanda 54
LT - Lituania 49
ZA - Sudafrica 43
AT - Austria 35
EC - Ecuador 33
IQ - Iraq 33
IR - Iran 21
AU - Australia 20
MA - Marocco 20
EG - Egitto 19
CL - Cile 18
PK - Pakistan 18
RO - Romania 18
CO - Colombia 17
UZ - Uzbekistan 17
VE - Venezuela 17
CH - Svizzera 16
SA - Arabia Saudita 13
UY - Uruguay 12
IL - Israele 11
PY - Paraguay 10
JO - Giordania 9
KE - Kenya 9
AE - Emirati Arabi Uniti 8
DO - Repubblica Dominicana 8
HR - Croazia 8
KZ - Kazakistan 8
TN - Tunisia 8
AL - Albania 7
AZ - Azerbaigian 7
EU - Europa 7
HU - Ungheria 7
LK - Sri Lanka 7
MY - Malesia 7
RS - Serbia 7
GR - Grecia 6
HN - Honduras 6
NG - Nigeria 6
PE - Perù 6
PT - Portogallo 6
AO - Angola 5
BY - Bielorussia 5
CZ - Repubblica Ceca 5
DZ - Algeria 5
NO - Norvegia 5
PH - Filippine 5
BH - Bahrain 4
CI - Costa d'Avorio 4
DK - Danimarca 4
NP - Nepal 4
OM - Oman 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
BO - Bolivia 3
CY - Cipro 3
ET - Etiopia 3
JM - Giamaica 3
LA - Repubblica Popolare Democratica del Laos 3
LU - Lussemburgo 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
PA - Panama 3
PR - Porto Rico 3
PS - Palestinian Territory 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BZ - Belize 2
EE - Estonia 2
GT - Guatemala 2
MC - Monaco 2
MD - Moldavia 2
SI - Slovenia 2
Totale 35.432
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Città #
Fairfield 2.310
Santa Clara 1.844
Southend 1.720
Ashburn 1.550
Singapore 1.310
Woodbridge 1.291
Houston 1.017
Chandler 1.007
Hong Kong 1.006
Seattle 913
Hefei 896
Cambridge 801
Jacksonville 749
Wilmington 741
Ann Arbor 603
Dearborn 577
Nyköping 572
London 486
Beijing 374
Warsaw 348
Modena 250
Los Angeles 238
Helsinki 237
Council Bluffs 229
Seoul 190
Chicago 186
San Diego 184
Princeton 169
San Jose 161
Ho Chi Minh City 159
Sofia 158
Dallas 156
New York 151
Munich 145
Eugene 135
Milan 135
The Dalles 132
Izmir 114
Jakarta 109
Des Moines 101
Bologna 99
Hanoi 99
Shanghai 93
São Paulo 87
Salt Lake City 83
Moscow 79
Buffalo 78
Brussels 56
Frankfurt am Main 56
Dublin 49
Rome 43
Tokyo 43
Columbus 40
Guangzhou 39
Bremen 38
Redwood City 38
Tampa 38
Elk Grove Village 37
Reggio Emilia 37
Boardman 35
Kent 35
Falls Church 34
Toronto 34
Groningen 32
Orem 32
Rio de Janeiro 31
Amsterdam 30
Mexico City 28
Parma 28
Phoenix 28
Denver 27
Atlanta 26
Norwalk 25
Nuremberg 25
Paris 25
Brooklyn 23
Chennai 23
Haiphong 23
Poplar 23
Redondo Beach 23
San Francisco 23
Saint Petersburg 22
Stockholm 22
Yalova 22
Belo Horizonte 21
Johannesburg 21
Washington 21
Boston 20
Montreal 20
Salamanca 20
Sterling 20
Kilburn 19
Kunming 19
Lancaster 19
Nanjing 19
Brasília 18
Dong Ket 18
Barcelona 17
Dhaka 17
Biên Hòa 16
Totale 25.570
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 1.058
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 421
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 382
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 360
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 350
BEAR, a Molecular Docking Refinement and Rescoring Method 346
Polypharmacology: challenges and opportunities in drug discovery 328
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 326
A rational approach to the design of flavones as xanthine oxidase inhibitors 323
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 319
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 314
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 295
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 294
Role of bifidobacteria in the hydrolysis of chlorogenic acid 290
Selection of protein conformations for structure-based polypharmacology studies 288
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 287
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 286
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 286
A model of the interaction of substrates and inhibitors with xanthine oxidase 285
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 285
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 285
On the integration of in silico drug design methods for drug repurposing 283
A computational workflow for the design of irreversible inhibitors of protein kinases 281
Advances and applications of binding affinity prediction methods in drug discovery 277
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 273
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 272
BEAR, a novel virtual screening methodology for drug discovery 272
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 271
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 270
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 266
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 265
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 261
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 261
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 260
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 259
Grid-enabled high throughput virtual screening 257
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 256
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 253
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 253
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 253
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 252
Structural bases for the inhibition of aldose reductase by phenolic compounds 251
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 250
αC helix displacement as a general approach for allosteric modulation of protein kinases 248
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 248
Identification of Target Associations for Polypharmacology from Analysis of Crystallographic Ligands of the Protein Data Bank 247
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 244
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 243
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 242
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 242
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 241
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 240
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 238
Virtual screening on large scale grids 238
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 237
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 235
Histone deacetylases: Structural determinants of inhibitor selectivity 234
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 234
Exploring the binding site of C-terminal Hsp90 inhibitors 233
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 231
ANTHOCYANIDINES AS INHIBITORS OF XANTHINE-OXIDASE 230
Solvent effects on the tautomerism of apigeninidin 230
Nitrophenyl derivatives as Aldose Reductase inhibitors 230
Computational polypharmacology analysis of the heat shock protein 90 interactome 228
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 227
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 227
Molecular docking: Shifting paradigms in drug discovery 227
Computational polypharmacology comes of age 225
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 223
Pharmacological approaches to the treatment of diabetic complications 222
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 221
Activité Antilipoperoxydante d'Extraits Polyphenoliques de Ribes Nigrum L. 220
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 220
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 218
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 217
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 217
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 216
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 216
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 214
Design and discovery of plasmepsin inhibitors using an automated workflow on large scale grids 214
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 212
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 211
Structure-based design of 7-carbamate analogs of geldanamycin 211
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 210
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 209
Targeting the Hsp90 interactome using in silico polypharmacology approaches 209
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 209
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 208
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 207
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity contants of variously hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition 206
Structure-based and in silico design of Hsp90 inhibitors 206
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 205
Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models 205
Fast and accurate predictions of relative binding free energies using MM-PBSA and MM-GBSA 203
G48A, a new KRAS mutation found in lung adenocarcinoma 203
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 203
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 200
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 199
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 198
Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor Tolrestat 198
Totale 25.833
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Categoria #
all - tutte 138.535
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 138.535
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.011 0 0 0 0 0 0 331 457 245 500 249 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.985 400 373 215 232 323 437 79 270 408 50 141 57
2023/20241.898 64 122 130 160 432 150 166 314 36 41 80 203
2024/20257.475 258 66 122 508 1.314 969 369 633 697 822 799 918
2025/20267.283 823 679 1.233 1.505 1.544 1.196 303 0 0 0 0 0
Totale 35.787