RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 14.570
EU - Europa 5.811
AS - Asia 2.091
SA - Sud America 30
AF - Africa 21
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 8
Totale 22.541
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Nazione #
US - Stati Uniti d'America 14.514
GB - Regno Unito 2.090
IT - Italia 1.044
SE - Svezia 907
SG - Singapore 653
CN - Cina 640
DE - Germania 600
HK - Hong Kong 382
UA - Ucraina 354
FI - Finlandia 203
TR - Turchia 192
BG - Bulgaria 157
FR - Francia 107
RU - Federazione Russa 80
BE - Belgio 55
ID - Indonesia 53
CA - Canada 50
IE - Irlanda 47
IN - India 44
LT - Lituania 41
BD - Bangladesh 34
NL - Olanda 33
VN - Vietnam 23
ES - Italia 20
JP - Giappone 20
BR - Brasile 16
IR - Iran 14
PL - Polonia 13
AU - Australia 10
CH - Svizzera 10
CL - Cile 10
KR - Corea 9
RO - Romania 8
EG - Egitto 7
EU - Europa 7
ZA - Sudafrica 7
GR - Grecia 6
HR - Croazia 6
AT - Austria 5
IL - Israele 5
MY - Malesia 5
NG - Nigeria 5
SA - Arabia Saudita 5
BY - Bielorussia 4
HU - Ungheria 4
CZ - Repubblica Ceca 3
NO - Norvegia 3
RS - Serbia 3
AE - Emirati Arabi Uniti 2
BZ - Belize 2
CO - Colombia 2
LK - Sri Lanka 2
MX - Messico 2
PH - Filippine 2
PR - Porto Rico 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AR - Argentina 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DZ - Algeria 1
EC - Ecuador 1
GE - Georgia 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LV - Lettonia 1
MD - Moldavia 1
OM - Oman 1
PK - Pakistan 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 22.541
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Città #
Fairfield 2.309
Southend 1.720
Woodbridge 1.291
Ashburn 1.188
Chandler 1.007
Houston 1.001
Seattle 905
Santa Clara 824
Cambridge 799
Jacksonville 746
Wilmington 723
Ann Arbor 603
Dearborn 577
Nyköping 572
Singapore 534
Hong Kong 376
Modena 219
Beijing 190
San Diego 183
Princeton 169
Sofia 155
Eugene 135
Izmir 114
Milan 103
Des Moines 101
New York 89
Helsinki 87
Bologna 76
London 75
Brussels 54
Jakarta 45
Frankfurt am Main 44
Dublin 43
Shanghai 42
Bremen 38
Redwood City 38
Falls Church 34
Boardman 32
Rome 32
Hefei 26
Toronto 26
Norwalk 25
Guangzhou 22
Saint Petersburg 22
Parma 20
Reggio Emilia 20
Kilburn 19
Munich 19
Dong Ket 18
Kunming 18
Nanjing 18
Chicago 17
Fremont 15
Hounslow 15
Grafing 13
Washington 13
Jinan 12
Phoenix 12
Amsterdam 11
Chiswick 11
Milwaukee 11
Ottawa 11
Verona 11
Siena 10
Frattamaggiore 9
Fuzhou 9
Los Angeles 9
Paris 9
San Francisco 9
Brescia 8
Dallas 8
Indiana 8
Meana Sardo 8
Nanchang 8
Serra 8
Wandsworth 8
Auburn Hills 7
Bergamo 7
Edinburgh 7
Philadelphia 7
Porto Mantovano 7
Renton 7
Shenzhen 7
Tokyo 7
Turin 7
Chengdu 6
Florence 6
Hangzhou 6
San Cesario sul Panaro 6
Trieste 6
West Jordan 6
Wuhan 6
Bari 5
Boston 5
Caorso 5
Carpi 5
Lappeenranta 5
Madrid 5
Orzinuovi 5
Piacenza 5
Totale 17.934
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 379
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 271
BEAR, a Molecular Docking Refinement and Rescoring Method 261
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 255
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 221
Selection of protein conformations for structure-based polypharmacology studies 220
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 217
Role of bifidobacteria in the hydrolysis of chlorogenic acid 216
On the integration of in silico drug design methods for drug repurposing 214
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 210
BEAR, a novel virtual screening methodology for drug discovery 210
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 208
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 205
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 204
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 204
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 203
Polypharmacology: challenges and opportunities in drug discovery 201
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 196
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 195
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 194
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 193
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 193
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 190
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 188
Advances and applications of binding affinity prediction methods in drug discovery 187
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 186
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 186
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 185
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 184
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 183
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 183
A rational approach to the design of flavones as xanthine oxidase inhibitors 182
A computational workflow for the design of irreversible inhibitors of protein kinases. 182
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 180
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 178
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 177
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 175
Histone deacetylases: Structural determinants of inhibitor selectivity 175
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 174
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 174
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 172
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 171
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 170
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 169
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 168
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 168
Structural bases for the inhibition of aldose reductase by phenolic compounds 167
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 167
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 167
αC helix displacement as a general approach for allosteric modulation of protein kinases 167
Exploring the binding site of C-terminal Hsp90 inhibitors 167
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 167
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 166
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 165
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 165
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 165
A model of the interaction of substrates and inhibitors with xanthine oxidase 164
Computational polypharmacology analysis of the heat shock protein 90 interactome 164
Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor Tolrestat 164
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 164
Solvent effects on the tautomerism of apigeninidin 163
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 163
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 162
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 161
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 160
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 159
Pharmacological approaches to the treatment of diabetic complications 157
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 157
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 157
Structure-based design of 7-carbamate analogs of geldanamycin 156
Computational polypharmacology comes of age 156
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 156
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 155
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 154
Nitrophenyl derivatives as Aldose Reductase inhibitors 154
Dimerization hot spots in the structure of human Hsp90 154
G48A, a new KRAS mutation found in lung adenocarcinoma 153
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 153
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 152
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 152
Grid-enabled high throughput virtual screening 151
Synthesis and Biological Evaluation of Migrastatin Macrotriazoles 151
Virtual screening on large scale grids 150
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 150
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 150
Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds 150
Targeting the Hsp90 interactome using in silico polypharmacology approaches 150
Binding estimation after refinement: BEARing out an innovative virtual screening methodology 149
Free energy perturbation studies on binding of the inhibitor 5,6-dihydrobenzo[h]cinnolin-3(2H)one-2-acetic acid and its methoxylated analogs to aldose reductase 147
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 146
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 144
Dual Kinase-Bromodomain Inhibitors in Anticancer Drug Discovery: A Structural and Pharmacological Perspective 144
Structure-based and in silico design of Hsp90 inhibitors 142
Molecular docking: Shifting paradigms in drug discovery 142
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 140
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 136
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 136
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 133
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 133
Exploiting computationally derived out-of-the-box protein conformations for drug design 132
Totale 17.486
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Categoria #
all - tutte 95.775
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 95.775
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.055 0 0 0 0 633 749 826 629 543 196 249 230
2020/20213.939 411 236 273 367 354 287 331 457 245 500 249 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.985 400 373 215 232 323 437 79 270 408 50 141 57
2023/20241.898 64 122 130 160 432 150 166 314 36 41 80 203
2024/20251.828 258 66 122 508 874 0 0 0 0 0 0 0
Totale 22.857