Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches

Costantino, Luca; Rastelli, Giulio; Vianello, P.; Cignarella, G.; Barlocco, D.

doi:10.1002/(SICI)1098-1128(199901)19:1<3::AID-MED2>3.3.CO;2-Z

Despite recent advances both in the chemistry and molecular pharmacology of antidiabetic drugs, diabetes still remains a life-threatening disease, which tends to spread all over the world. The clinical profile of diabetic subjects is often worsened by the presence of several long-term complications, namely neuropathy, nephropathy, retinopathy, and cataract. Several attempts have been made to prevent or at least to delay them. The most relevant are reported in this review, including the development of compounds acting as aldose reductase inhibitors, anti-advanced glycation end- product drugs, free radical scavengers, vasoactive agents, essential fatty acid supplementation, and neurotropic growth factors.

Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches / Costantino, Luca; Rastelli, Giulio; P., Vianello; G., Cignarella; D., Barlocco. - In: MEDICINAL RESEARCH REVIEWS. - ISSN 0198-6325. - STAMPA. - 19(1999), pp. 3-23.

Data di pubblicazione:	1999
Titolo:	Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches
Autore/i:	Costantino, Luca; Rastelli, Giulio; P., Vianello; G., Cignarella; D., Barlocco
Autore/i UNIMORE:	COSTANTINO, Luca RASTELLI, Giulio P. VIANELLO G. CIGNARELLA D. BARLOCCO mostra contributor esterni nascondi contributor esterni
Digital Object Identifier (DOI):	http://dx.doi.org/10.1002/(SICI)1098-1128(199901)19:1<3::AID-MED2>3.3.CO;2-Z
Rivista:	MEDICINAL RESEARCH REVIEWS
Volume:	19
Pagina iniziale:	3
Pagina finale:	23
Codice identificativo ISI:	WOS:000077641400001
Codice identificativo Scopus:	2-s2.0-0032959371
Codice identificativo Pubmed:	9918192
Citazione:	Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches / Costantino, Luca; Rastelli, Giulio; P., Vianello; G., Cignarella; D., Barlocco. - In: MEDICINAL RESEARCH REVIEWS. - ISSN 0198-6325. - STAMPA. - 19(1999), pp. 3-23.
Tipologia	Articolo su rivista

File in questo prodotto:

File	Descrizione	Tipologia
Diabetes complications and their potential prevention Aldose reductase inhibition and other approaches .pdf		Versione dell'editore (versione pubblicata)	Administrator Richiedi una copia

Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11380/458209

Citazioni

I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris