IL-17 Ligand and Receptor Family Members Are Differentially Expressed by Keratinocyte Subpopulations and Modulate Their Differentiation and Inflammatory Phenotype

Psoriasis is a chronic inflammatory skin disease characterized by dysregulation of the interleukin 17 (IL-17) signaling axis. Given that psoriasis development depends on keratinocyte stem cells and early progenitors' sensitivity to differentiation, we analyzed IL-17 ligands and the expression and function of in a novel subset of keratinocyte subpopulations: keratinocyte stem cells (KSC) and early and late Transit Amplifying (ETA or LTA, respectively) cells. We found that all subpopulations ex...

Disordered plasmonic system with dense copper nano-island morphology

Neuroendocrine Effects of Carnitines on Reproductive Impairments

Conclusive Insight into the Coordination Complexes of a Flexible Bis(beta-diketonato) Ligand and their Phase-dependent Structure: a Multi-technique Approach

Multichelating ligands with nuclear spin-free donor atoms are of particular interest for creating stable electronic spin qubits based on paramagnetic transition metal ions. We recently focused on the coordinating ability of the bis(beta-diketonato) ligand bdhb2–, featuring two “acac” moieties connected through a 1,3-phenylene bridge (H2bdhb = 1,3-bis(3,5-dioxo-1-hexyl)benzene). The two crystalline complexes of bdhb2– so far isolated and structurally characterized, namely [(VO)2(bdhb)2] (1) an...