VENTURELLI, Alberto
 Distribuzione geografica
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Continente #
NA - Nord America 7.066
EU - Europa 4.628
AS - Asia 1.357
SA - Sud America 26
AF - Africa 10
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 13.098
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Nazione #
US - Stati Uniti d'America 7.026
IT - Italia 1.464
GB - Regno Unito 1.172
DE - Germania 599
SE - Svezia 495
CN - Cina 481
SG - Singapore 436
FR - Francia 202
UA - Ucraina 157
HK - Hong Kong 133
FI - Finlandia 126
RU - Federazione Russa 96
TR - Turchia 77
PL - Polonia 66
BG - Bulgaria 65
ID - Indonesia 56
IN - India 56
BE - Belgio 55
CA - Canada 38
JP - Giappone 30
IE - Irlanda 28
LT - Lituania 22
VN - Vietnam 19
NL - Olanda 17
CH - Svizzera 16
IR - Iran 16
MY - Malesia 13
CZ - Repubblica Ceca 11
TW - Taiwan 11
CL - Cile 9
KR - Corea 9
AR - Argentina 7
BR - Brasile 7
ES - Italia 6
PT - Portogallo 6
EU - Europa 5
RO - Romania 5
AU - Australia 4
DK - Danimarca 4
PH - Filippine 4
PK - Pakistan 4
RS - Serbia 4
MA - Marocco 3
TZ - Tanzania 3
AT - Austria 2
BO - Bolivia 2
IL - Israele 2
IQ - Iraq 2
MD - Moldavia 2
MX - Messico 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
SA - Arabia Saudita 2
ZA - Sudafrica 2
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
CO - Colombia 1
EG - Egitto 1
ET - Etiopia 1
GR - Grecia 1
HU - Ungheria 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LV - Lettonia 1
MK - Macedonia 1
NP - Nepal 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 13.098
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Città #
Santa Clara 978
Southend 926
Fairfield 726
Chandler 567
Woodbridge 501
Ashburn 491
Houston 404
Singapore 354
Frankfurt am Main 318
Seattle 317
Ann Arbor 316
Jacksonville 314
Nyköping 308
Modena 291
Wilmington 269
Cambridge 263
Dearborn 263
Hong Kong 121
Beijing 113
New York 109
San Diego 84
Helsinki 80
Princeton 74
Sofia 65
Shanghai 64
Kraków 62
Fremont 61
Jakarta 56
Eugene 54
Izmir 48
Bologna 45
Brussels 45
Moscow 45
Boardman 44
Milan 44
Redwood City 42
Bremen 36
Grafing 29
London 29
Des Moines 25
Dublin 24
Milwaukee 23
Parma 23
Guangzhou 22
Ottawa 21
Munich 20
Rome 20
Hefei 18
Brescia 17
Nanjing 16
Turin 16
Washington 16
Padova 15
Reggio Emilia 15
Dong Ket 14
San Mateo 13
Bagheria 12
Norwalk 12
Toronto 12
Brno 11
Falls Church 11
Kunming 11
Los Angeles 11
Prato 11
Verona 11
Napoli 10
Sassuolo 10
Formigine 9
Leawood 9
Paris 9
Perugia 9
Piacenza 9
Albinea 8
Dallas 8
Ferrara 8
Florence 8
Jinan 8
Misterbianco 8
Osnabrück 8
Torino 8
Argenta 7
Bari 7
Berlin 7
Leuven 7
Zurich 7
Carpi 6
Pavia 6
Rossdorf 6
San Giorgio Del Sannio 6
Wuhan 6
Ardabil 5
Bomporto 5
Central 5
Ho Chi Minh City 5
Indiana 5
Lisbon 5
Pescara 5
Philadelphia 5
Rimini 5
Albino 4
Totale 9.619
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Nome #
TYDOCK PHARMA s.r.l. Spin Off dell'Università di Modena e Reggio Emilia che ha come fine l'attività di ricerca e sviluppo nel settore delle biotech farmaceutiche. 450
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase 344
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase 313
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases 306
USO DI INIBITORI DELLA PTERIDINA REDUTTASI PER LA PREVENZIONE E/O IL TRATTAMENTO DI INFEZIONI PARASSITARIE 300
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 274
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 261
Biological evaluation of MR36, a novel non-polyglutamatable thymidylate synthase inhibitor that blocks cell cycle progression in melanoma cell lines. 249
Decoding the structural basis for carbapenem hydrolysis by class A β- lactamases: fishing for a pharmacophore 245
Constrained dansyl derivatives reveal bacterial specificity of highly conserved Thymidylate Synthases A 235
Permeation through the cell membrane of a boron-based β-lactamase inhibitor. 230
X-ray-crystallography deciphers the activity of broad spectrum boronic acid β-Lactamases inhibitors 226
“A step further in the discovery of phthalein derivatives as Thymidylate Synthase inhibitors” 222
Structure-based studies on species-specific inhibition of thymidylate synthase 218
Thymidylate synthase structure, function and implication in drug discovery 218
Multiligand approach to the identification of resistant strains overexpressing beta-lactamase 218
Design and characterization of a mutation outside the active site of human thymidylate synthase that affects ligand binding. 215
Maxwell A: F1000Prime Recommendation of Evaluation [Neres J et al., ACS Chem Biol 2014]. In F1000Prime, 09 Jan 2015; DOI: 10.3410/f.725248139.793502885. F1000Prime.com/725248139#eval793502885 214
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors 213
Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-beta-lactamases 213
IN SILICO/IN VITRO APPROACHES FOR THE IDENTIFICATION OF NEW CARBAPENEMASE INHIBITORS 207
Allosteric Inhibition of human Thymidylate Synthase. 203
Tethering low affinity ligands to the dimeric interface of human thymidylate synthase. 201
Optimization of N-alkylation in the Synthesis of Methotrexate and Pteridine-based Derivatives Under Microwave-Irradiation 197
ANTICANCER DRUGS 194
Optimizing Cell Permeation of an Antibiotic Resistance Inhibitor for Improved Efficacy 194
QUINOXALINE DERIVATIVES AS ANTITUBERCULOSIS AGENTS 190
Improving specificity vs bacterial thymidylate synthases through N-dansyl modulation of didansyltyrosine 189
Long period fiber grating biosensor for the detection of drug resistant bacteria: The 'OPTObacteria' project 184
Feasibility Study on a Measurement Method and a Portable Measuring System to Estimate the Concentration of Cloxacillin and β -Lactamase in Milk 183
New thymidylate synthase inhibitors induce apoptosis in melanoma cell lines 181
Target-based approaches for the discovery of new antimycobacterial drugs 179
Targeting Class A and C Serine β-Lactamases with a Broad-Spectrum Boronic Acid Derivative 175
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 174
Pirrole-amidine oligopeptide–DNA interaction studies through Isothermal Titration Calorimetry 170
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer-US8916679 “B2 - Granted patent as second publication”. 168
MALDI-TOF MS as a tool for rapid Identification of Low Protein Affinity Drug Fragments. 166
Fragment Based Discovery of Thymidylate Synthase Dimeric Interface Inhibitors Through Mass Spectrometry. Invited lecture to the Fragment Based Lead Discovery track. 165
Label-free fiber optic optrode for the detection of class C beta-lactamases expressed by drug resistant bacteria 161
Crystallographic studies of novel inhibitors of [beta]-lactamases 156
The Inhibition of Extended Spectrum beta-Lactamases: Hits and Leads 154
Merging disulphide bonds for drug design Interfering with a cancer key protein 154
Dal Ligand based design di inibitori della Timidilato Sintasi all'Analisi Comparativa dei Complessi Enzima-Inibitore 153
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer 152
Pharmacological and toxicological evaluation of a new series of thymidylate synthase inhibitors as anticancer agents 150
Naphthofuranone derivatives as specific inhibitors of thymidylate synthases 148
NAPHTHOFURANONE DERIVATIVES AS SPECIFIC INHIBITORS OF THYMIDYLATE SYNTHASES 147
Developing New beta-Lactamase Inhibitors Through Structure-Based Design and Pharmacokinetic Improvement 145
A new strategy based on microwave-assisted technology for the extraction and purification of beeswax policosanols for pharmaceutical purposes and beyond 145
Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase 144
Nuovo trattamento assistito da microonde per la produzione di miscele arricchite in policosanoli da matrici cerose 140
Scaffolds and Biological Targets Avenue to Fight Against Drug Resistance in Leishmaniasis 138
Long period fiber grating working in reflection mode as valuable biosensing platform for the detection of drug resistant bacteria 133
Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases 126
Rapid-Throughput Technologies Applied to the Discovery of New Hits against Thymidylate synthase Enzymes 117
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 115
Structural and thermodynamic combined studies for inhibitors binding to Thymidylate Synthase 115
Structural and Thermodynamic analysis of novel inhibitors of beta-lactmases. 115
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 108
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 105
Studi termodinamici e strutturali dell’interazione tra derivati densilici e Timidilato Sintasi Batteriche 102
Current Treatments to Control African Trypanosomiasis and One Health Perspective 102
Quinoxaline chemistry. Part 15. 4-[2-Quinoxalylmethylenimino]- benzoylglutamates and -benzoates, 4-[2-quinoxalylmethyl-N-methylamino]- benzoylglutamates as analogues of classical antifolate agents. Synthesis, elucidation of structures and in vitro evaluation of antifolate and anticancer activities 100
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 97
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 96
VIrtual screening identifies cross-class inhibitors of clinically relevant serine- and metallo-beta lactamases 93
On the feasibility of a CENTA-based biosensor to measure antibiotics concentration in milk 86
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 85
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 83
First total synthesis of the irciniasulfonic acids 81
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 77
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 75
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 73
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 70
Reflection-type long period grating biosensor for detection of drug resistant bacteria: The OptoBacteria project 63
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 63
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 60
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 56
Reflection-type long period grating biosensor for the detection of drug resistant bacteria: The Opto-bacteria Project 54
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective 51
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 49
On the feasibility of a CENTA-based biosensor to measure antibiotics concentration in milk 38
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents 31
An innovative method for the extraction and HPLC analysis of bioactive policosanols from non-psychoactive Cannabis sativa L. 27
Intersite Communication in Dimeric Enzymes Highlighted by Structural and Thermodynamic Analysis of Didansyltyrosine Binding to Thymidylate Synthases 27
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 22
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 22
Totale 13.288
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Categoria #
all - tutte 53.470
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.470
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.395 0 0 0 0 0 273 323 231 186 88 117 177
2020/20212.210 176 99 201 202 377 173 164 176 100 281 170 91
2021/20221.483 56 135 83 63 82 151 70 89 180 110 297 167
2022/20231.837 237 223 136 174 176 245 72 152 243 25 79 75
2023/20241.643 71 90 116 111 543 146 55 142 36 32 143 158
2024/20251.906 154 45 137 249 767 554 0 0 0 0 0 0
Totale 13.288