Synthetic compounds of 1, 2 -naphthalein molecules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed.
Naphthofuranone derivatives as specific inhibitors of thymidylate synthases / Venturelli, Alberto; Costi, Maria Paola; Pecorari, Piergiorgio; Rossi, Tiziana; Casolari, Chiara; Tondi, Donatella; Barlocco, Daniela. - (2008).
Naphthofuranone derivatives as specific inhibitors of thymidylate synthases
VENTURELLI, Alberto;COSTI, Maria Paola;PECORARI, Piergiorgio;ROSSI, Tiziana;TONDI, Donatella;
2008
Abstract
Synthetic compounds of 1, 2 -naphthalein molecules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed.
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