TONDI, Donatella
TONDI, Donatella
Dipartimento di Scienze della Vita
"Structure-Based Discovery & In parallel Optimization of Novel Inhibitors of Thymidylate Synthase"
1997 Tondi, D.; Slomczynska, U.; Ghelli, S.; Wattweson, D. M.; Costi, M. P.; Shoichet, B. K.
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors
1997 S., Ghelli; Costi, Maria Paola; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Rastelli, Giulio
3-Aminophenylboronic acid derivative inhibitors of beta-lactamases, their preparation, and their therapeutic use.
1998 SHOICHET BRIAN, K.; Costi, Maria Paola; Tondi, Donatella
3-Aminophenylboronic acid derivative inhibitors of β-lactamases, their preparation, and their therapeutic use
2000 Shoichet, B. K.; Costi, Maria Paola; Tondi, Donatella
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases
2020 Linciano, Pasquale; Gianquinto, Eleonora; Montanari, Martina; Maso, Lorenzo; Bellio, Pierangelo; Cebrián-Sastre, Esmeralda; Celenza, Giuseppe; Blázquez, Jesús; Cendron, Laura; Spyrakis, Francesca; Tondi, Donatella
A multidisciplinary approach in the successful identification of novel carbapenemases inhibitors
2019 Tondi, D.
A multidisciplinary approach to the design of novel inhibitors for KPC-2
2017 Celenza, Giuseppe; Bellio, Pierangelo; Linciano, Pasquale; Perilli, Mariagrazia; Cendron, Laura; Tondi, Donatella
Acyclic boronic acids mimic β-Lactamases tetrahedral intermediates leading to broad spectrum inhibitors
2019 Tondi, D.
Amide Boronic Acid Inhibitors of AmpC b-lactamase to Reverse Bacterial Resistance to b-lactam Antibiotics.
1999 Shoichet, B. K.; Tondi, Donatella; Costi, Maria Paola; M., P.
AmpC beta-lactamase in complex with 3-(3-nitro-phenylsulfamoyl)-thiophene-2-carboxylic acid
2005 Tondi, Donatella
AmpC beta-lactamase in complex with 5-diformylaminomethyl-benzo[b]thiophen-2-boronic acid
2007 Tondi, Donatella
AmpC beta-lactamase in complex with a p.carboxyphenylboronic acid
2009 Tondi, Donatella
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases
2016 QUOTADAMO, ANTONIO; LINCIANO, PASQUALE; DAVOLI, Paolo; TONDI, Donatella; COSTI, Maria Paola; VENTURELLI, Alberto
Antibiotic Drug Discovery: New Targets and Molecular Entities.
2018 Tondi, D.
ANTICANCER DRUGS
2015 Costantino, Luca; Costi, Maria Paola; Ponterini, Glauco; Marverti, Gaetano; Franchini, Silvia; Tondi, Donatella; D'Arca, Domenico; Ferrari, Stefania; Luciani, Rosaria; Venturelli, Alberto; Sammak, Susan; Lauriola, Angela; Gozzi, Gaia
Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors?
2020 Gianquinto, E.; Tondi, D.; D'Arrigo, G.; Lazzarato, L.; Spyrakis, F.
Characterisation and Optimisation of Anti-LexA Nanobodies Targeting the SOS-response Pathway to Fight Antibiotic Resistance
2022 Campagnaro, Enrica; Vascon, Filippo; Maso, Lorenzo; Chinellato, Monica; Goormaghtigh, Frédéric; Bellio, Pierangelo; Van Melderen, Laurence; Ruzzene, Maria; Pardon, Els; Angelini, Alessandro; Celenza, Giuseppe; Steyaert, Jan; Tondi, Donatella; Cendron, Laura
Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-beta-lactamases
2017 Santucci, Matteo; Spyrakis, Francesca; Cross, Simon; Quotadamo, Antonio; Farina, Davide; Tondi, Donatella; De Luca, Filomena; Docquier, Jean-Denis; Prieto, Ana Isabel; Ibacache, Claudia; Blázquez, Jesús; Venturelli, Alberto; Cruciani, Gabriele; Costi, Maria Paola
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations
1996 S., Ghelli; Rastelli, Giulio; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Costi, Maria Paola
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth
2018 Saxena, Puneet; Severi, Leda; Santucci, Matteo; Taddia, Laura; Ferrari, Stefania; Luciani, Rosaria; Marverti, Gaetano; Marraccini, Chiara; Tondi, Donatella; Mor, Marco; Laura, Scalvini; Vitiello, Simone; Losi, Lorena; Fonda, Sergio; Pacifico, Salvatore; Guerrini, Remo; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
"Structure-Based Discovery & In parallel Optimization of Novel Inhibitors of Thymidylate Synthase" | 1-gen-1997 | Tondi, D.; Slomczynska, U.; Ghelli, S.; Wattweson, D. M.; Costi, M. P.; Shoichet, B. K. | |
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors | 1-gen-1997 | S., Ghelli; Costi, Maria Paola; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Rastelli, Giulio | |
3-Aminophenylboronic acid derivative inhibitors of beta-lactamases, their preparation, and their therapeutic use. | 16-dic-1998 | SHOICHET BRIAN, K.; Costi, Maria Paola; Tondi, Donatella | |
3-Aminophenylboronic acid derivative inhibitors of β-lactamases, their preparation, and their therapeutic use | 22-giu-2000 | Shoichet, B. K.; Costi, Maria Paola; Tondi, Donatella | |
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases | 1-gen-2020 | Linciano, Pasquale; Gianquinto, Eleonora; Montanari, Martina; Maso, Lorenzo; Bellio, Pierangelo; Cebrián-Sastre, Esmeralda; Celenza, Giuseppe; Blázquez, Jesús; Cendron, Laura; Spyrakis, Francesca; Tondi, Donatella | |
A multidisciplinary approach in the successful identification of novel carbapenemases inhibitors | 1-gen-2019 | Tondi, D. | |
A multidisciplinary approach to the design of novel inhibitors for KPC-2 | 1-gen-2017 | Celenza, Giuseppe; Bellio, Pierangelo; Linciano, Pasquale; Perilli, Mariagrazia; Cendron, Laura; Tondi, Donatella | |
Acyclic boronic acids mimic β-Lactamases tetrahedral intermediates leading to broad spectrum inhibitors | 1-gen-2019 | Tondi, D. | |
Amide Boronic Acid Inhibitors of AmpC b-lactamase to Reverse Bacterial Resistance to b-lactam Antibiotics. | 16-dic-1999 | Shoichet, B. K.; Tondi, Donatella; Costi, Maria Paola; M., P. | |
AmpC beta-lactamase in complex with 3-(3-nitro-phenylsulfamoyl)-thiophene-2-carboxylic acid | 1-gen-2005 | Tondi, Donatella | |
AmpC beta-lactamase in complex with 5-diformylaminomethyl-benzo[b]thiophen-2-boronic acid | 1-gen-2007 | Tondi, Donatella | |
AmpC beta-lactamase in complex with a p.carboxyphenylboronic acid | 1-gen-2009 | Tondi, Donatella | |
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases | 1-gen-2016 | QUOTADAMO, ANTONIO; LINCIANO, PASQUALE; DAVOLI, Paolo; TONDI, Donatella; COSTI, Maria Paola; VENTURELLI, Alberto | |
Antibiotic Drug Discovery: New Targets and Molecular Entities. | 1-gen-2018 | Tondi, D. | |
ANTICANCER DRUGS | 1-gen-2015 | Costantino, Luca; Costi, Maria Paola; Ponterini, Glauco; Marverti, Gaetano; Franchini, Silvia; Tondi, Donatella; D'Arca, Domenico; Ferrari, Stefania; Luciani, Rosaria; Venturelli, Alberto; Sammak, Susan; Lauriola, Angela; Gozzi, Gaia | |
Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors? | 1-gen-2020 | Gianquinto, E.; Tondi, D.; D'Arrigo, G.; Lazzarato, L.; Spyrakis, F. | |
Characterisation and Optimisation of Anti-LexA Nanobodies Targeting the SOS-response Pathway to Fight Antibiotic Resistance | 1-gen-2022 | Campagnaro, Enrica; Vascon, Filippo; Maso, Lorenzo; Chinellato, Monica; Goormaghtigh, Frédéric; Bellio, Pierangelo; Van Melderen, Laurence; Ruzzene, Maria; Pardon, Els; Angelini, Alessandro; Celenza, Giuseppe; Steyaert, Jan; Tondi, Donatella; Cendron, Laura | |
Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-beta-lactamases | 1-gen-2017 | Santucci, Matteo; Spyrakis, Francesca; Cross, Simon; Quotadamo, Antonio; Farina, Davide; Tondi, Donatella; De Luca, Filomena; Docquier, Jean-Denis; Prieto, Ana Isabel; Ibacache, Claudia; Blázquez, Jesús; Venturelli, Alberto; Cruciani, Gabriele; Costi, Maria Paola | |
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations | 1-gen-1996 | S., Ghelli; Rastelli, Giulio; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Costi, Maria Paola | |
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth | 1-gen-2018 | Saxena, Puneet; Severi, Leda; Santucci, Matteo; Taddia, Laura; Ferrari, Stefania; Luciani, Rosaria; Marverti, Gaetano; Marraccini, Chiara; Tondi, Donatella; Mor, Marco; Laura, Scalvini; Vitiello, Simone; Losi, Lorena; Fonda, Sergio; Pacifico, Salvatore; Guerrini, Remo; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola |