COSTI, Maria Paola
COSTI, Maria Paola
Dipartimento di Scienze della Vita
"Structure-Based Discovery & In parallel Optimization of Novel Inhibitors of Thymidylate Synthase"
1997 Tondi, D.; Slomczynska, U.; Ghelli, S.; Wattweson, D. M.; Costi, M. P.; Shoichet, B. K.
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors
1997 S., Ghelli; Costi, Maria Paola; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Rastelli, Giulio
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes
2014 Piras, Sandra; Carta, Antonio; Briguglio, Irene; Corona, Paola; Paglietti, Giuseppe; Luciani, Rosaria; Costi, Maria Paola; Ferrari, Stefania
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
2015 Neres, João; Hartkoorn, Ruben C.; Chiarelli, Laurent R.; Gadupudi, Ramakrishna; Pasca, Maria Rosalia; Mori, Giorgia; Venturelli, Alberto; Savina, Svetlana; Makarov, Vadim; Kolly, Gaelle S.; Molteni, Elisabetta; Binda, Claudia; Dhar, Neeraj; Ferrari, Stefania; Brodin, Priscille; Delorme, Vincent; Landry, Valérie; de Jesus Lopes Ribeiro, Ana Luisa; Farina, Davide Salvatore Francesco; Saxena, Puneet; Pojer, Florence; Carta, Antonio; Luciani, Rosaria; Porta, Alessio; Zanoni, Giuseppe; De Rossi, Edda; Costi, Maria Paola; Riccardi, Giovanna; Cole, Stewart T.
2′-Deoxyuridine 5′-Monophosphate Substrate Displacement in Thymidylate Synthase through 6-Hydroxy-2H-naphtho[1,8-bc]furan-2-one Derivatives
2013 Ferrari, Stefania; Calò, S; Leone, R; Luciani, Rosaria; Costantino, Luca; Sammak, Susan; Di Pisa, F; Pozzi, C; Mangani, S; Costi, Maria Paola
3-Aminophenylboronic acid derivative inhibitors of beta-lactamases, their preparation, and their therapeutic use.
1998 SHOICHET BRIAN, K.; Costi, Maria Paola; Tondi, Donatella
3-Aminophenylboronic acid derivative inhibitors of β-lactamases, their preparation, and their therapeutic use
2000 Shoichet, B. K.; Costi, Maria Paola; Tondi, Donatella
[Use of amikacin in renal pathology]
1981 Triolo, G; Mangiarotti, G; Pacitti, A; Jeantet, A; Paola, M; Messina, M; Cardelli, R; Randone, D F; Porcellini, G; Martini, P F; Segoloni, G P
A condensed thiadiazolo-pyrimidine as a new efficient fluorophore. Theoretical and experimental investigation of the electronic spectra and photophysics
1994 Baraldi, Ivan; Carnevali, A.; Caselli, Monica; Costi, Maria Paola; Pecorari, P.; Ponterini, Glauco; Rinaldi, M.
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates.
2023 Tagliazucchi, Lorenzo; Perea-Martinez, Ana; Fiorini, Greta; Ignacio Manzano, José; García-Hernández, Raquel; Genovese, Filippo; Pinetti, Diego; Gamarro, Francisco; Costi, Maria Paola
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells
2020 Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Francesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana Grazia; Costi, Maria Paola; D'Arca, Domenico
A proteomic approach to investigate the mechanism of action of anticancer peptides
2013 Genovese, Filippo; Gualandi, Alessandra; Taddia, Laura; Caselli, Monica; Ponterini, Glauco; Ferrari, Stefania; Marverti, Gaetano; R., Guerrini; M., Pela'; Pavesi, Giorgia; C., Trapella; Costi, Maria Paola
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties
2022 Tagliazucchi, Lorenzo; Venturelli, Alberto; Malpezzi, Giulia; Moschella, MARIA GAETANA; Aiello, Daniele; Lopresti, Ludovica; Pozzi, Cecilia; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
2019 Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz
ACS Medicinal Chemistry Letters. member of the Editorial Board
2014 Costi, Maria Paola
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes
2019 Romito, Filippo; Tagliazucchi, Lorenzo; Pozzi, Cecilia; Mangani, Stefano; Lopresti, Ludovica; Ponterini, Glauco; Costi, Maria Paola
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics
2024 Malpezzi, Giulia; Di Persio, Sara; Tagliazucchi, Lorenzo; Aiello, Daniele; Venturelli, Alberto; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Ponterini, Glauco; Costi, Maria Paola
Alanine Mutants of the Interface Residues of Human Thymidylate Synthase Decode Key Features of the Binding Mode of Allosteric Anticancer Peptides
2015 Tochowicz, Anna Maria; Santucci, Matteo; Saxena, Puneet; Guaitoli, Giambattista; Costi, Maria Paola
Allosteric Inhibition of human Thymidylate Synthase.
2010 S., Henrich; O., Salo Ahen; D., Garg; Cardinale, Daniela; Ferrari, Stefania; Franchini, Silvia; Genovese, Filippo; Guaitoli, Giambattista; Lazzari, Sandra; Venturelli, Alberto; S., Mangani; Costi, Maria Paola; R. C., Wade
Alternative strategies in medicinal chemistry to face drug resistance in anticancer therapy.
2006 Cardinale, Daniela; Ferrari, Stefania; Franchini, Silvia; Corsini, Enrico; Battini, Renata; Costi, Maria Paola
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| "Structure-Based Discovery & In parallel Optimization of Novel Inhibitors of Thymidylate Synthase" | 1-gen-1997 | Tondi, D.; Slomczynska, U.; Ghelli, S.; Wattweson, D. M.; Costi, M. P.; Shoichet, B. K. | |
| 1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors | 1-gen-1997 | S., Ghelli; Costi, Maria Paola; D., Barlocco; M., Rinaldi; Tondi, Donatella; P., Pecorari; Rastelli, Giulio | |
| 2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes | 1-gen-2014 | Piras, Sandra; Carta, Antonio; Briguglio, Irene; Corona, Paola; Paglietti, Giuseppe; Luciani, Rosaria; Costi, Maria Paola; Ferrari, Stefania | |
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 | 1-gen-2015 | Neres, João; Hartkoorn, Ruben C.; Chiarelli, Laurent R.; Gadupudi, Ramakrishna; Pasca, Maria Rosalia; Mori, Giorgia; Venturelli, Alberto; Savina, Svetlana; Makarov, Vadim; Kolly, Gaelle S.; Molteni, Elisabetta; Binda, Claudia; Dhar, Neeraj; Ferrari, Stefania; Brodin, Priscille; Delorme, Vincent; Landry, Valérie; de Jesus Lopes Ribeiro, Ana Luisa; Farina, Davide Salvatore Francesco; Saxena, Puneet; Pojer, Florence; Carta, Antonio; Luciani, Rosaria; Porta, Alessio; Zanoni, Giuseppe; De Rossi, Edda; Costi, Maria Paola; Riccardi, Giovanna; Cole, Stewart T. | |
| 2′-Deoxyuridine 5′-Monophosphate Substrate Displacement in Thymidylate Synthase through 6-Hydroxy-2H-naphtho[1,8-bc]furan-2-one Derivatives | 1-gen-2013 | Ferrari, Stefania; Calò, S; Leone, R; Luciani, Rosaria; Costantino, Luca; Sammak, Susan; Di Pisa, F; Pozzi, C; Mangani, S; Costi, Maria Paola | |
| 3-Aminophenylboronic acid derivative inhibitors of beta-lactamases, their preparation, and their therapeutic use. | 16-dic-1998 | SHOICHET BRIAN, K.; Costi, Maria Paola; Tondi, Donatella | |
| 3-Aminophenylboronic acid derivative inhibitors of β-lactamases, their preparation, and their therapeutic use | 22-giu-2000 | Shoichet, B. K.; Costi, Maria Paola; Tondi, Donatella | |
| [Use of amikacin in renal pathology] | 1-gen-1981 | Triolo, G; Mangiarotti, G; Pacitti, A; Jeantet, A; Paola, M; Messina, M; Cardelli, R; Randone, D F; Porcellini, G; Martini, P F; Segoloni, G P | |
| A condensed thiadiazolo-pyrimidine as a new efficient fluorophore. Theoretical and experimental investigation of the electronic spectra and photophysics | 1-gen-1994 | Baraldi, Ivan; Carnevali, A.; Caselli, Monica; Costi, Maria Paola; Pecorari, P.; Ponterini, Glauco; Rinaldi, M. | |
| A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates. | 1-gen-2023 | Tagliazucchi, Lorenzo; Perea-Martinez, Ana; Fiorini, Greta; Ignacio Manzano, José; García-Hernández, Raquel; Genovese, Filippo; Pinetti, Diego; Gamarro, Francisco; Costi, Maria Paola | |
| A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells | 1-gen-2020 | Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Francesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana Grazia; Costi, Maria Paola; D'Arca, Domenico | |
| A proteomic approach to investigate the mechanism of action of anticancer peptides | 1-gen-2013 | Genovese, Filippo; Gualandi, Alessandra; Taddia, Laura; Caselli, Monica; Ponterini, Glauco; Ferrari, Stefania; Marverti, Gaetano; R., Guerrini; M., Pela'; Pavesi, Giorgia; C., Trapella; Costi, Maria Paola | |
| A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties | 1-gen-2022 | Tagliazucchi, Lorenzo; Venturelli, Alberto; Malpezzi, Giulia; Moschella, MARIA GAETANA; Aiello, Daniele; Lopresti, Ludovica; Pozzi, Cecilia; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola | |
| Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform | 1-gen-2019 | Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz | |
| ACS Medicinal Chemistry Letters. member of the Editorial Board | 1-gen-2014 | Costi, Maria Paola | |
| Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes | 1-gen-2019 | Romito, Filippo; Tagliazucchi, Lorenzo; Pozzi, Cecilia; Mangani, Stefano; Lopresti, Ludovica; Ponterini, Glauco; Costi, Maria Paola | |
| Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics | 1-gen-2024 | Malpezzi, Giulia; Di Persio, Sara; Tagliazucchi, Lorenzo; Aiello, Daniele; Venturelli, Alberto; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Ponterini, Glauco; Costi, Maria Paola | |
| Alanine Mutants of the Interface Residues of Human Thymidylate Synthase Decode Key Features of the Binding Mode of Allosteric Anticancer Peptides | 1-gen-2015 | Tochowicz, Anna Maria; Santucci, Matteo; Saxena, Puneet; Guaitoli, Giambattista; Costi, Maria Paola | |
| Allosteric Inhibition of human Thymidylate Synthase. | 1-gen-2010 | S., Henrich; O., Salo Ahen; D., Garg; Cardinale, Daniela; Ferrari, Stefania; Franchini, Silvia; Genovese, Filippo; Guaitoli, Giambattista; Lazzari, Sandra; Venturelli, Alberto; S., Mangani; Costi, Maria Paola; R. C., Wade | |
| Alternative strategies in medicinal chemistry to face drug resistance in anticancer therapy. | 1-gen-2006 | Cardinale, Daniela; Ferrari, Stefania; Franchini, Silvia; Corsini, Enrico; Battini, Renata; Costi, Maria Paola |