Pirolidine derivatives such as Distamicine and derivatives can interact with TATA box that are present in DNA of plasmodium phalciparum, therefore these compounds may be studied as potential antimalarial compounds.
Pirrole-amidine oligopeptide–DNA interaction studies through Isothermal Titration Calorimetry / Venturelli, Alberto; Guaitoli, Giambattista; Cancian, Laura; P., Lombardi; Costi, Maria Paola. - STAMPA. - 1:(2007), pp. 38-38. (Intervento presentato al convegno Proceeding of the COST B22 Expert meeting on Drug Evaluation tenutosi a Basilea nel 20-21 November).