Synthetic compounds of 1, 2 -naphthalein molecules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed
NAPHTHOFURANONE DERIVATIVES AS SPECIFIC INHIBITORS OF THYMIDYLATE SYNTHASES / Costi, Maria Paola; Rossi, Tiziana; Casolari, Chiara; Tondi, Donatella; Barlocco, Daniela; Pecorari, Piergiorgio; Venturelli, Alberto. - (2006 Jul 05).
NAPHTHOFURANONE DERIVATIVES AS SPECIFIC INHIBITORS OF THYMIDYLATE SYNTHASES
COSTI, Maria Paola;ROSSI, Tiziana;CASOLARI, Chiara;TONDI, Donatella;BARLOCCO, Daniela;PECORARI, Piergiorgio;VENTURELLI, Alberto
2006
Abstract
Synthetic compounds of 1, 2 -naphthalein molecules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed
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