BRASILI, Livio
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 14.933
EU - Europa 9.016
AS - Asia 6.288
SA - Sud America 928
AF - Africa 77
OC - Oceania 38
Continente sconosciuto - Info sul continente non disponibili 9
Totale 31.289
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 14.750
GB - Regno Unito 2.849
CN - Cina 2.294
SG - Singapore 1.713
SE - Svezia 1.337
IT - Italia 1.242
DE - Germania 1.168
HK - Hong Kong 986
BR - Brasile 776
FI - Finlandia 525
RU - Federazione Russa 476
UA - Ucraina 422
TR - Turchia 281
VN - Vietnam 265
FR - Francia 210
KR - Corea 199
BG - Bulgaria 178
IN - India 174
BE - Belgio 155
CA - Canada 114
NL - Olanda 109
IE - Irlanda 88
RO - Romania 59
ID - Indonesia 58
PL - Polonia 54
AR - Argentina 51
JP - Giappone 47
MX - Messico 42
LT - Lituania 40
IR - Iran 39
BD - Bangladesh 37
IQ - Iraq 30
EC - Ecuador 28
IL - Israele 27
PK - Pakistan 26
NZ - Nuova Zelanda 24
ES - Italia 22
ZA - Sudafrica 22
CL - Cile 16
CO - Colombia 16
VE - Venezuela 15
CH - Svizzera 13
OM - Oman 13
AU - Australia 12
BY - Bielorussia 12
AT - Austria 11
PY - Paraguay 11
SA - Arabia Saudita 11
AE - Emirati Arabi Uniti 10
KE - Kenya 10
TW - Taiwan 9
CI - Costa d'Avorio 8
CZ - Repubblica Ceca 8
EG - Egitto 8
EU - Europa 8
KZ - Kazakistan 8
PT - Portogallo 8
MA - Marocco 7
NP - Nepal 6
PE - Perù 6
TH - Thailandia 6
UZ - Uzbekistan 6
AZ - Azerbaigian 5
DZ - Algeria 5
LU - Lussemburgo 5
MY - Malesia 5
PH - Filippine 5
UY - Uruguay 5
BZ - Belize 4
CR - Costa Rica 4
EE - Estonia 4
LK - Sri Lanka 4
NO - Norvegia 4
AM - Armenia 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
JO - Giordania 3
LB - Libano 3
NG - Nigeria 3
PR - Porto Rico 3
TN - Tunisia 3
UG - Uganda 3
AL - Albania 2
AO - Angola 2
BH - Bahrain 2
BO - Bolivia 2
CU - Cuba 2
DK - Danimarca 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
IS - Islanda 2
KH - Cambogia 2
MM - Myanmar 2
NI - Nicaragua 2
PA - Panama 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
Totale 31.266
Salva come PNG Salva come JPEG
Città #
Southend 1.851
Santa Clara 1.350
Fairfield 1.108
Singapore 1.026
Woodbridge 992
Hong Kong 959
Ashburn 933
Chandler 913
Hefei 887
Jacksonville 873
Houston 833
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
London 522
Seattle 457
Wilmington 436
Beijing 383
Cambridge 353
Helsinki 336
Dallas 334
Chicago 280
New York 279
Los Angeles 261
Modena 257
Seoul 191
Sofia 177
Eugene 165
Princeton 161
Brussels 154
San Diego 141
Izmir 134
Des Moines 126
Council Bluffs 120
Moscow 98
Ho Chi Minh City 96
Buffalo 93
Salt Lake City 92
The Dalles 90
Dublin 85
Milan 81
Shanghai 80
Amsterdam 68
São Paulo 68
Hanoi 60
Elk Grove Village 59
Fremont 53
Redwood City 50
Tampa 48
Toronto 47
Yalova 45
Norwalk 41
Bremen 40
Boardman 37
Guangzhou 37
Warsaw 37
Columbus 35
Kent 35
Shenzhen 35
Tokyo 35
Philadelphia 34
Falls Church 33
Bologna 32
Frankfurt am Main 31
Kunming 31
Rome 29
West Jordan 28
Turku 27
Jakarta 25
Sterling 25
Auckland 24
Augusta 24
Horia 24
Boston 23
Nanjing 23
Phoenix 23
Verona 23
Belo Horizonte 22
Jyväskylä 22
Orem 22
San Francisco 22
Sochi 22
Brooklyn 21
Grafing 21
Leawood 21
Rio de Janeiro 21
Lancaster 19
Stockholm 19
Mexico City 18
Montreal 18
Curitiba 17
Jerusalem 17
Mumbai 17
Nuremberg 17
Paris 17
Porto Alegre 17
San Mateo 17
Atlanta 16
Denver 16
Totale 21.860
Salva come PNG Salva come JPEG
Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 721
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 698
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 613
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 602
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 597
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 516
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 469
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 439
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 409
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 407
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 405
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 396
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 387
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 379
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 365
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 332
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 324
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 321
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 318
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 315
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 307
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 305
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 297
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 290
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 289
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 288
Evaluation of stereo and chemical stability of chiral compounds 287
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 286
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 282
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 279
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 279
Discovery of a new series of 5-HT1A receptor agonists 277
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 254
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 247
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 247
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 246
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 245
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 243
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 239
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 238
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 230
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 230
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 230
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 229
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 229
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 218
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 216
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 214
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 214
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 210
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 209
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 207
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 205
Insights into the structure of the Human TAAR5 receptor: a computational study 203
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 202
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 202
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 202
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 201
An unexpected central hypertensive effect of the new imidazoline compound benazoline 199
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 199
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 197
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 196
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 194
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 193
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 190
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 187
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 186
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 184
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 183
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 180
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 176
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 175
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 174
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 174
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 172
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 169
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 164
Fallot's tetralogy and squatting position 164
Derivati 1,3-Diossanici come Antagonisti Muscarinici 163
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 161
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 161
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 160
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 159
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 158
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 158
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 158
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 156
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 155
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 153
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 153
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 153
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 152
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 152
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 147
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 147
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 146
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 145
N,N"-(DITHIO-2,1-ETIIANEDIYL)BIS{N'-(PYRROL-2-YLMETI{YL)-1,6-HEXANEDIAMINE}(PYREXTRAMINE), A NEW IRREVERSIBLE a,.ADRENORECEPTOR BLOCKING AGENTTHE TETRAMINE DISULFIDE CLASS 144
Alpha2-Adrenoceptors Profile Modulation anf High Antinociceptove Activity of (S)-)2-[1-(Biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 143
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 142
Totale 25.311
Salva come PNG Salva come JPEG
Categoria #
all - tutte 111.312
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 111.312
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.764 0 0 0 0 0 195 315 321 203 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/20265.805 687 570 1.264 1.299 1.559 426 0 0 0 0 0 0
Totale 31.516