BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 10.575
EU - Europa 6.555
AS - Asia 1.345
AF - Africa 17
SA - Sud America 17
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 7
Totale 18.524
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Nazione #
US - Stati Uniti d'America 10.502
GB - Regno Unito 2.296
SE - Svezia 1.191
IT - Italia 1.068
DE - Germania 597
CN - Cina 559
UA - Ucraina 399
HK - Hong Kong 331
FI - Finlandia 240
TR - Turchia 213
FR - Francia 178
BG - Bulgaria 176
BE - Belgio 141
IN - India 85
IE - Irlanda 82
RU - Federazione Russa 70
CA - Canada 60
RO - Romania 50
IR - Iran 36
SG - Singapore 23
NL - Olanda 16
IL - Israele 15
ID - Indonesia 14
JP - Giappone 14
CH - Svizzera 12
OM - Oman 9
EU - Europa 8
PK - Pakistan 8
VN - Vietnam 8
BR - Brasile 7
CI - Costa d'Avorio 7
PL - Polonia 7
CL - Cile 6
ES - Italia 6
KR - Corea 6
MX - Messico 6
PT - Portogallo 5
MY - Malesia 4
NZ - Nuova Zelanda 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BY - Bielorussia 3
BZ - Belize 3
CO - Colombia 3
EG - Egitto 3
LU - Lussemburgo 3
TH - Thailandia 3
TW - Taiwan 3
UG - Uganda 3
AM - Armenia 2
CZ - Repubblica Ceca 2
EE - Estonia 2
IQ - Iraq 2
LK - Sri Lanka 2
NG - Nigeria 2
NO - Norvegia 2
PR - Porto Rico 2
SA - Arabia Saudita 2
AL - Albania 1
AO - Angola 1
AT - Austria 1
BD - Bangladesh 1
BH - Bahrain 1
CR - Costa Rica 1
DK - Danimarca 1
GR - Grecia 1
HU - Ungheria 1
IS - Islanda 1
KZ - Kazakistan 1
ME - Montenegro 1
RS - Serbia 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
TT - Trinidad e Tobago 1
VE - Venezuela 1
Totale 18.524
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Città #
Southend 1.851
Fairfield 1.108
Woodbridge 992
Chandler 913
Jacksonville 870
Houston 822
Ann Arbor 784
Ashburn 563
Nyköping 555
Dearborn 553
Seattle 452
Wilmington 413
Cambridge 353
Hong Kong 308
Modena 242
Beijing 205
Sofia 175
New York 167
Eugene 165
Princeton 161
Brussels 141
San Diego 141
Izmir 134
Des Moines 123
Helsinki 109
Dublin 79
Fremont 52
Redwood City 50
Munich 47
Milan 46
Norwalk 41
Bremen 40
London 38
Falls Church 33
Boardman 32
Philadelphia 32
Shenzhen 30
Toronto 30
Kunming 29
Hefei 28
Shanghai 28
West Jordan 28
Horia 24
Augusta 23
Verona 23
Grafing 21
Leawood 21
Rome 21
Bologna 20
Nanjing 19
San Mateo 17
Saint Petersburg 15
San Francisco 15
Los Angeles 14
Auburn Hills 13
Jerusalem 13
Parma 13
Guangzhou 12
Umeå 12
Zanjan 12
Chiswick 11
Hounslow 11
Indiana 11
Jinan 11
Kilburn 11
Paris 11
Pasadena 11
San Jose 11
Bengaluru 10
Brooklyn 10
Romainville 10
Tulsa 10
Mcallen 9
Nanchang 9
Nuremberg 9
Ottawa 9
Timisoara 9
Bandung 8
Florence 8
Las Vegas 8
Montréal 8
Naples 8
Old Bridge 8
Padova 8
Palermo 8
Turin 8
Abidjan 7
Albuquerque 7
Andover 7
Dong Ket 7
Mountain View 7
Napoli 7
Phoenix 7
St Petersburg 7
Trieste 7
Acton 6
Catania 6
Frankfurt am Main 6
Fuzhou 6
Monmouth Junction 6
Totale 13.609
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Nome #
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 490
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 345
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 310
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 308
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 287
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 283
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 282
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 271
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 268
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 259
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 222
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 218
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 217
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 214
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 198
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 196
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 196
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 193
Evaluation of stereo and chemical stability of chiral compounds 192
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 188
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 185
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 184
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 182
Discovery of a new series of 5-HT1A receptor agonists 176
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 176
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 176
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 176
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 175
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 174
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 173
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 172
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 171
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 169
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 167
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 165
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 158
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 154
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 154
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 152
Insights into the structure of the Human TAAR5 receptor: a computational study 150
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 145
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 142
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 140
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 138
An unexpected central hypertensive effect of the new imidazoline compound benazoline 135
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 133
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 131
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 130
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 130
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 127
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 126
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 124
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 124
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 124
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 124
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 123
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 120
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 120
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 119
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 118
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 118
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 117
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 117
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 117
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 117
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 116
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 115
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 113
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 113
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 112
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 109
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 108
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 106
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 105
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 104
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 102
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 101
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 100
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 99
Resolution of the potent α1-adrenoreceptor antagonist 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-1,4-benzoxathian (benoxathian) 97
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 96
Structure_Activity Relationships among Methoctramine-Related Polymethylene Tetramine. Chain Length and Substituent Effects on M2 Muscarinic Receptor Blocking Activity. 95
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 93
Nuova Serie di Ligandi Sigma a Struttura Piperazinica e Piperidinica 93
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 92
Alpha2-Adrenoceptors Profile Modulation anf High Antinociceptove Activity of (S)-)2-[1-(Biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 92
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 92
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 91
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 90
MOLECULAR PROPERTIES OF THE ADRENERGIC a-RECEPTORIII - Origin of topographicol duqlism in the reaction of a receptor thiolwith symmetrical and unsymmetrical polyamine disulfides. 90
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 89
Fallot's tetralogy and squatting position 89
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 88
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 88
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 86
Structure-Activity Relationships at alpha1-Adrenoceptor Subtypes within a New Series of 1,3-Dioxolane Derivatives 86
Derivati 1,3-Diossanici come Antagonisti Muscarinici 84
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 84
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 83
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 83
Totale 15.069
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Categoria #
all - tutte 61.821
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.821
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019741 0 0 0 0 0 0 0 0 0 0 416 325
2019/20203.514 360 183 93 187 411 493 595 303 345 107 228 209
2020/20213.052 335 122 227 282 322 195 315 321 203 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.623 57 108 163 162 465 176 128 241 35 88 0 0
Totale 18.747