BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 12.249
EU - Europa 8.469
AS - Asia 2.657
SA - Sud America 193
AF - Africa 29
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 8
Totale 23.617
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Nazione #
US - Stati Uniti d'America 12.157
GB - Regno Unito 2.786
SE - Svezia 1.233
IT - Italia 1.186
DE - Germania 1.066
SG - Singapore 941
CN - Cina 758
FI - Finlandia 495
RU - Federazione Russa 426
HK - Hong Kong 411
UA - Ucraina 409
TR - Turchia 224
FR - Francia 192
BG - Bulgaria 176
BR - Brasile 158
BE - Belgio 153
IN - India 117
NL - Olanda 88
IE - Irlanda 84
CA - Canada 76
RO - Romania 52
IR - Iran 36
LT - Lituania 34
ID - Indonesia 32
IL - Israele 19
PL - Polonia 19
JP - Giappone 18
PK - Pakistan 14
CH - Svizzera 13
OM - Oman 11
BY - Bielorussia 9
VN - Vietnam 9
AU - Australia 8
CL - Cile 8
CO - Colombia 8
ES - Italia 8
EU - Europa 8
IQ - Iraq 8
CI - Costa d'Avorio 7
CZ - Repubblica Ceca 7
PT - Portogallo 7
AR - Argentina 6
KR - Corea 6
MX - Messico 6
TW - Taiwan 6
VE - Venezuela 6
AT - Austria 5
EG - Egitto 5
TH - Thailandia 5
ZA - Sudafrica 5
LK - Sri Lanka 4
LU - Lussemburgo 4
MY - Malesia 4
NZ - Nuova Zelanda 4
AE - Emirati Arabi Uniti 3
AM - Armenia 3
BD - Bangladesh 3
BZ - Belize 3
EE - Estonia 3
NO - Norvegia 3
UG - Uganda 3
UY - Uruguay 3
UZ - Uzbekistan 3
AO - Angola 2
AZ - Azerbaigian 2
DO - Repubblica Dominicana 2
EC - Ecuador 2
HU - Ungheria 2
KH - Cambogia 2
KZ - Kazakistan 2
NG - Nigeria 2
NP - Nepal 2
PH - Filippine 2
PR - Porto Rico 2
SA - Arabia Saudita 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
BH - Bahrain 1
BO - Bolivia 1
CR - Costa Rica 1
DK - Danimarca 1
DZ - Algeria 1
GR - Grecia 1
HR - Croazia 1
IS - Islanda 1
JO - Giordania 1
KE - Kenya 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MA - Marocco 1
ME - Montenegro 1
MM - Myanmar 1
PA - Panama 1
PY - Paraguay 1
RS - Serbia 1
SC - Seychelles 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
Totale 23.613
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Città #
Southend 1.851
Santa Clara 1.334
Fairfield 1.108
Woodbridge 992
Chandler 913
Jacksonville 870
Houston 822
Ann Arbor 784
Ashburn 613
Nyköping 555
Dearborn 553
London 513
Singapore 500
Munich 481
Seattle 454
Wilmington 413
Hong Kong 388
Cambridge 353
Helsinki 333
Modena 252
Beijing 215
Sofia 175
New York 167
Eugene 165
Princeton 161
Brussels 153
San Diego 141
Izmir 134
Des Moines 123
Moscow 94
Council Bluffs 90
Dublin 81
Milan 69
Amsterdam 64
Chicago 54
Fremont 52
Redwood City 50
Shanghai 42
Norwalk 41
Bremen 40
Toronto 40
Boardman 36
Falls Church 33
Bologna 32
Philadelphia 32
Shenzhen 30
Kunming 29
Hefei 28
West Jordan 28
Rome 27
Los Angeles 26
Guangzhou 25
Horia 24
Augusta 23
Verona 23
Jyväskylä 22
Grafing 21
Leawood 21
Frankfurt am Main 20
Jakarta 20
Nanjing 19
San Mateo 17
Parma 16
Bengaluru 15
Saint Petersburg 15
San Francisco 15
Jerusalem 14
Ottawa 14
Auburn Hills 13
Nuremberg 13
Jinan 12
Paris 12
Umeå 12
Zanjan 12
Chiswick 11
Falkenstein 11
Hounslow 11
Indiana 11
Kilburn 11
Pasadena 11
San Jose 11
São Paulo 11
Brooklyn 10
Padova 10
Romainville 10
Tulsa 10
Wuhan 10
Belo Horizonte 9
Mcallen 9
Nanchang 9
Naples 9
Timisoara 9
Warsaw 9
Bandung 8
Florence 8
Fuzhou 8
Las Vegas 8
Montréal 8
Old Bridge 8
Palermo 8
Totale 17.180
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Nome #
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 537
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 458
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 429
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 421
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 399
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 386
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 369
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 351
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 328
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 326
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 313
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 312
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 302
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 274
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 259
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 255
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 254
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 244
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 243
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 240
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 230
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 227
Evaluation of stereo and chemical stability of chiral compounds 225
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 225
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 217
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 216
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 213
Discovery of a new series of 5-HT1A receptor agonists 211
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 211
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 210
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 209
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 209
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 200
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 199
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 198
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 198
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 195
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 192
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 184
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 180
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 180
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 178
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 178
Insights into the structure of the Human TAAR5 receptor: a computational study 176
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 175
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 175
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 173
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 171
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 170
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 163
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 161
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 159
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 158
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 155
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 154
An unexpected central hypertensive effect of the new imidazoline compound benazoline 153
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 152
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 151
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 151
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 149
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 149
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 147
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 146
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 143
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 142
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 142
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 141
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 141
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 141
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 139
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 136
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 135
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 132
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 132
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 131
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 131
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 130
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 127
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 127
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 126
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 125
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 124
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 123
Nuova Serie di Ligandi Sigma a Struttura Piperazinica e Piperidinica 123
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 122
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 122
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 122
Derivati 1,3-Diossanici come Antagonisti Muscarinici 121
Fallot's tetralogy and squatting position 121
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 120
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 119
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 118
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 118
Structure_Activity Relationships among Methoctramine-Related Polymethylene Tetramine. Chain Length and Substituent Effects on M2 Muscarinic Receptor Blocking Activity. 118
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 118
Alpha2-Adrenoceptors Profile Modulation anf High Antinociceptove Activity of (S)-)2-[1-(Biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 116
Resolution of the potent α1-adrenoreceptor antagonist 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-1,4-benzoxathian (benoxathian) 114
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 113
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 112
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 112
Totale 19.250
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Categoria #
all - tutte 87.499
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.499
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020889 0 0 0 0 0 0 0 0 345 107 228 209
2020/20213.052 335 122 227 282 322 195 315 321 203 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20254.861 288 81 113 404 1.108 854 707 461 845 0 0 0
Totale 23.844