BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 15.111
EU - Europa 9.037
AS - Asia 6.411
SA - Sud America 964
AF - Africa 82
OC - Oceania 39
Continente sconosciuto - Info sul continente non disponibili 9
Totale 31.653
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Nazione #
US - Stati Uniti d'America 14.923
GB - Regno Unito 2.850
CN - Cina 2.301
SG - Singapore 1.808
SE - Svezia 1.337
IT - Italia 1.246
DE - Germania 1.169
HK - Hong Kong 986
BR - Brasile 803
FI - Finlandia 535
RU - Federazione Russa 476
UA - Ucraina 422
TR - Turchia 281
VN - Vietnam 268
FR - Francia 210
KR - Corea 201
BG - Bulgaria 178
IN - India 176
BE - Belgio 155
CA - Canada 115
NL - Olanda 109
IE - Irlanda 88
RO - Romania 59
ID - Indonesia 58
PL - Polonia 54
AR - Argentina 51
JP - Giappone 47
MX - Messico 44
BD - Bangladesh 40
LT - Lituania 40
IR - Iran 39
IQ - Iraq 32
EC - Ecuador 31
PK - Pakistan 29
IL - Israele 27
NZ - Nuova Zelanda 24
ES - Italia 23
ZA - Sudafrica 22
CL - Cile 18
CO - Colombia 16
VE - Venezuela 15
OM - Oman 14
AT - Austria 13
AU - Australia 13
CH - Svizzera 13
BY - Bielorussia 12
KE - Kenya 12
PY - Paraguay 12
SA - Arabia Saudita 12
AE - Emirati Arabi Uniti 10
MA - Marocco 9
TW - Taiwan 9
CI - Costa d'Avorio 8
CZ - Repubblica Ceca 8
EG - Egitto 8
EU - Europa 8
KZ - Kazakistan 8
PT - Portogallo 8
UY - Uruguay 7
AZ - Azerbaigian 6
NP - Nepal 6
PE - Perù 6
PH - Filippine 6
TH - Thailandia 6
UZ - Uzbekistan 6
DZ - Algeria 5
LU - Lussemburgo 5
MY - Malesia 5
BZ - Belize 4
CR - Costa Rica 4
EE - Estonia 4
LB - Libano 4
LK - Sri Lanka 4
NG - Nigeria 4
NO - Norvegia 4
AL - Albania 3
AM - Armenia 3
BO - Bolivia 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
JO - Giordania 3
PA - Panama 3
PR - Porto Rico 3
RS - Serbia 3
TN - Tunisia 3
UG - Uganda 3
AO - Angola 2
BH - Bahrain 2
CU - Cuba 2
DK - Danimarca 2
DM - Dominica 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
IS - Islanda 2
KH - Cambogia 2
MM - Myanmar 2
NI - Nicaragua 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
Totale 31.629
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Città #
Southend 1.851
Santa Clara 1.353
Fairfield 1.109
Singapore 1.104
Woodbridge 992
Ashburn 966
Hong Kong 959
Chandler 913
Hefei 887
Jacksonville 875
Houston 836
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
London 522
Seattle 458
Wilmington 436
Beijing 383
Cambridge 353
Helsinki 346
Dallas 336
Chicago 291
New York 283
Los Angeles 270
Modena 257
Seoul 191
Sofia 177
Eugene 165
Princeton 161
Brussels 154
San Diego 142
Izmir 134
Des Moines 126
Council Bluffs 123
The Dalles 107
Ho Chi Minh City 98
Moscow 98
Salt Lake City 95
Buffalo 93
Dublin 85
Milan 83
Shanghai 80
São Paulo 69
Amsterdam 68
Hanoi 60
Elk Grove Village 59
Fremont 53
Redwood City 50
Tampa 50
Toronto 47
Yalova 45
Norwalk 41
Bremen 40
Boardman 39
Guangzhou 37
Warsaw 37
Columbus 35
Kent 35
Philadelphia 35
Shenzhen 35
Tokyo 35
Falls Church 33
Bologna 32
Frankfurt am Main 32
Kunming 31
San Jose 30
Rome 29
West Jordan 28
Turku 27
Orem 26
Sterling 26
Jakarta 25
Auckland 24
Augusta 24
Horia 24
Phoenix 24
Boston 23
Nanjing 23
Rio de Janeiro 23
Verona 23
Belo Horizonte 22
Jyväskylä 22
San Francisco 22
Sochi 22
Brooklyn 21
Grafing 21
Leawood 21
Mexico City 20
Lancaster 19
Montreal 19
Stockholm 19
Curitiba 17
Denver 17
Jerusalem 17
Mumbai 17
Nuremberg 17
Paris 17
Porto Alegre 17
San Mateo 17
Totale 22.078
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 729
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 704
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 615
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 606
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 602
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 520
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 471
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 441
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 414
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 409
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 408
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 400
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 390
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 382
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 370
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 338
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 335
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 327
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 322
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 319
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 311
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 311
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 297
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 294
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 294
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 293
Evaluation of stereo and chemical stability of chiral compounds 289
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 289
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 285
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 284
Discovery of a new series of 5-HT1A receptor agonists 283
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 282
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 260
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 252
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 250
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 249
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 249
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 247
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 240
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 239
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 237
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 235
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 232
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 231
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 230
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 219
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 218
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 216
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 215
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 214
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 212
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 209
Insights into the structure of the Human TAAR5 receptor: a computational study 207
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 207
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 205
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 204
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 204
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 203
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 203
An unexpected central hypertensive effect of the new imidazoline compound benazoline 201
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 201
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 199
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 197
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 194
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 193
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 189
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 187
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 186
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 185
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 181
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 179
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 178
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 177
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 175
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 174
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 170
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 167
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 166
Derivati 1,3-Diossanici come Antagonisti Muscarinici 165
Fallot's tetralogy and squatting position 165
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 163
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 161
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 161
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 160
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 159
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 158
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 158
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 156
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 155
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 155
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 154
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 154
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 154
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 154
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 151
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 149
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 149
N,N"-(DITHIO-2,1-ETIIANEDIYL)BIS{N'-(PYRROL-2-YLMETI{YL)-1,6-HEXANEDIAMINE}(PYREXTRAMINE), A NEW IRREVERSIBLE a,.ADRENORECEPTOR BLOCKING AGENTTHE TETRAMINE DISULFIDE CLASS 144
Alpha2-Adrenoceptors Profile Modulation anf High Antinociceptove Activity of (S)-)2-[1-(Biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 143
IDENTIFICATION OF POTENT 1,3-DIOXOLANE-BASED 5-HT1A RECEPTOR AGONISTS FOR THE TREATMENTS OF CNS DISORDERS AND PAIN 143
Totale 25.611
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Categoria #
all - tutte 112.299
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 112.299
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.764 0 0 0 0 0 195 315 321 203 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/20266.169 687 570 1.264 1.299 1.559 790 0 0 0 0 0 0
Totale 31.880