BRASILI, Livio
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 19.373
EU - Europa 10.249
AS - Asia 8.490
SA - Sud America 1.251
Continente sconosciuto - Info sul continente non disponibili 236
AF - Africa 167
OC - Oceania 42
Totale 39.808
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 18.964
GB - Regno Unito 2.897
CN - Cina 2.481
SG - Singapore 2.324
IT - Italia 1.570
DE - Germania 1.539
SE - Svezia 1.346
HK - Hong Kong 1.068
BR - Brasile 967
VN - Vietnam 938
FI - Finlandia 724
RU - Federazione Russa 483
UA - Ucraina 435
FR - Francia 366
TR - Turchia 290
IN - India 277
KR - Corea 262
BD - Bangladesh 252
CA - Canada 231
BG - Bulgaria 181
BE - Belgio 162
NL - Olanda 127
IE - Irlanda 93
AR - Argentina 86
ID - Indonesia 80
MX - Messico 74
IQ - Iraq 73
PL - Polonia 67
JP - Giappone 66
RO - Romania 62
EC - Ecuador 49
PK - Pakistan 46
CO - Colombia 42
ES - Italia 42
IR - Iran 40
LT - Lituania 40
IL - Israele 33
ZA - Sudafrica 33
CL - Cile 32
PH - Filippine 31
VE - Venezuela 31
AE - Emirati Arabi Uniti 30
KE - Kenya 24
NZ - Nuova Zelanda 24
CR - Costa Rica 23
SA - Arabia Saudita 23
MA - Marocco 22
EG - Egitto 21
OM - Oman 17
PY - Paraguay 17
AU - Australia 16
CH - Svizzera 16
TH - Thailandia 16
UZ - Uzbekistan 16
AT - Austria 15
BY - Bielorussia 14
JM - Giamaica 14
JO - Giordania 14
MY - Malesia 14
KZ - Kazakistan 13
TN - Tunisia 13
TW - Taiwan 13
AZ - Azerbaigian 11
DZ - Algeria 11
EE - Estonia 11
NP - Nepal 11
CZ - Repubblica Ceca 10
CI - Costa d'Avorio 9
PR - Porto Rico 9
PT - Portogallo 9
UY - Uruguay 9
AL - Albania 8
ET - Etiopia 8
EU - Europa 8
GT - Guatemala 8
LB - Libano 8
NI - Nicaragua 8
PE - Perù 8
BO - Bolivia 7
HN - Honduras 7
DO - Repubblica Dominicana 6
BH - Bahrain 5
CY - Cipro 5
LK - Sri Lanka 5
LU - Lussemburgo 5
SC - Seychelles 5
TT - Trinidad e Tobago 5
BZ - Belize 4
HU - Ungheria 4
NG - Nigeria 4
NO - Norvegia 4
PS - Palestinian Territory 4
SN - Senegal 4
UG - Uganda 4
AG - Antigua e Barbuda 3
AM - Armenia 3
DK - Danimarca 3
PA - Panama 3
RS - Serbia 3
SI - Slovenia 3
Totale 39.521
Salva come PNG Salva come JPEG
Città #
Ashburn 1.966
Southend 1.851
Santa Clara 1.450
Singapore 1.430
Fairfield 1.109
Hong Kong 1.026
Woodbridge 992
Chandler 913
San Jose 890
Hefei 887
Jacksonville 877
Houston 846
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
Council Bluffs 543
Helsinki 533
London 527
Seattle 462
Wilmington 443
Beijing 433
Dallas 384
Cambridge 360
Chicago 360
New York 360
Los Angeles 347
Berlin 315
Ho Chi Minh City 279
Modena 259
Seoul 244
Hanoi 230
The Dalles 194
Sofia 177
Milan 175
Eugene 166
Princeton 161
Brussels 159
San Diego 147
Izmir 135
Lauterbourg 131
Des Moines 128
Buffalo 124
Columbus 110
Moscow 99
São Paulo 97
Salt Lake City 96
Shanghai 89
Dublin 88
Toronto 76
Amsterdam 74
Orem 67
Elk Grove Village 62
Frankfurt am Main 59
Fremont 56
Tokyo 54
Tampa 52
Da Nang 51
Phoenix 51
Redwood City 50
Warsaw 47
Rome 46
Boardman 45
Philadelphia 45
Yalova 45
Norwalk 42
Bremen 40
Bologna 38
Guangzhou 38
Kent 36
Shenzhen 35
Mexico City 34
Mumbai 34
Falls Church 33
Denver 32
Haiphong 32
Kunming 31
Brooklyn 29
Naples 29
Atlanta 28
Rio de Janeiro 28
West Jordan 28
Augusta 27
Jakarta 27
Miano 27
Paris 27
San Francisco 27
Turku 27
Boston 26
Sterling 26
Falkenstein 25
Auckland 24
Belo Horizonte 24
Hillsboro 24
Horia 24
Miami 24
Montreal 24
Nanjing 24
Verona 24
Baghdad 22
Totale 26.937
Salva come PNG Salva come JPEG
Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 1.004
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 843
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 830
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 769
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 656
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 596
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 547
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 521
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 473
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 462
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 458
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 456
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 456
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 440
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 429
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 402
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 402
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 396
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 388
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 381
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 365
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 358
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 355
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 353
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 346
Discovery of a new series of 5-HT1A receptor agonists 343
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 342
Evaluation of stereo and chemical stability of chiral compounds 342
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 341
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 328
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 325
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 324
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 319
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 318
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 313
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 310
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 309
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 304
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 303
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 301
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 290
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 287
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 286
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 285
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 283
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 282
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 276
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 274
Insights into the structure of the Human TAAR5 receptor: a computational study 273
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 272
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 272
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 264
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 263
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 262
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 262
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 262
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 259
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 254
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 253
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 251
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 250
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 248
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 247
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 245
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 238
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 238
Fallot's tetralogy and squatting position 238
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 234
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 232
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 232
An unexpected central hypertensive effect of the new imidazoline compound benazoline 228
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 226
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 225
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 225
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 225
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 224
Effect of the replacement of the o-methoxyphenyl moiety with nitrogen-containing aromatic rings within N-phenyl-piperazine and phenoxy-ethylamine-based 1,3-dioxo/oxathio/dithiolanes as α1 and 5-HT1A receptor ligands 222
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 220
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 218
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 214
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 213
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 212
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 210
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 210
Derivati 1,3-Diossanici come Antagonisti Muscarinici 210
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 209
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 208
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 208
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 202
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 200
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 198
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 198
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 196
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 195
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 195
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 195
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 194
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 193
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 193
Molecular properties of the adrenergic alpha-receptors.4.Topographical and structural differences betweentissue-specific binding sites as revealedby benextramine and analogues. 190
Totale 31.576
Salva come PNG Salva come JPEG
Categoria #
all - tutte 136.443
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 136.443
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.109 0 0 0 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/202611.425 687 570 1.264 1.299 1.559 812 1.214 662 1.065 1.250 551 492
2026/20272.672 374 682 1.239 377 0 0 0 0 0 0 0 0
Totale 39.808