BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 18.778
EU - Europa 10.218
AS - Asia 8.487
SA - Sud America 1.234
Continente sconosciuto - Info sul continente non disponibili 236
AF - Africa 166
OC - Oceania 42
Totale 39.161
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Nazione #
US - Stati Uniti d'America 18.392
GB - Regno Unito 2.886
CN - Cina 2.481
SG - Singapore 2.323
IT - Italia 1.561
DE - Germania 1.539
SE - Svezia 1.343
HK - Hong Kong 1.068
BR - Brasile 951
VN - Vietnam 938
FI - Finlandia 724
RU - Federazione Russa 483
UA - Ucraina 435
FR - Francia 366
TR - Turchia 290
IN - India 277
KR - Corea 262
BD - Bangladesh 252
CA - Canada 214
BG - Bulgaria 181
BE - Belgio 162
NL - Olanda 126
IE - Irlanda 93
AR - Argentina 86
ID - Indonesia 79
IQ - Iraq 73
MX - Messico 73
PL - Polonia 67
JP - Giappone 65
RO - Romania 62
EC - Ecuador 49
PK - Pakistan 46
CO - Colombia 42
ES - Italia 41
IR - Iran 40
LT - Lituania 40
IL - Israele 33
ZA - Sudafrica 33
CL - Cile 31
PH - Filippine 31
VE - Venezuela 31
AE - Emirati Arabi Uniti 30
KE - Kenya 24
NZ - Nuova Zelanda 24
CR - Costa Rica 23
SA - Arabia Saudita 23
MA - Marocco 22
EG - Egitto 21
OM - Oman 17
PY - Paraguay 17
AU - Australia 16
CH - Svizzera 16
TH - Thailandia 16
UZ - Uzbekistan 16
AT - Austria 15
BY - Bielorussia 14
JM - Giamaica 14
JO - Giordania 14
MY - Malesia 14
KZ - Kazakistan 13
TN - Tunisia 13
TW - Taiwan 13
AZ - Azerbaigian 11
DZ - Algeria 11
NP - Nepal 11
CZ - Repubblica Ceca 10
CI - Costa d'Avorio 9
PR - Porto Rico 9
PT - Portogallo 9
UY - Uruguay 9
AL - Albania 8
ET - Etiopia 8
EU - Europa 8
LB - Libano 8
NI - Nicaragua 8
PE - Perù 8
BO - Bolivia 7
GT - Guatemala 7
HN - Honduras 7
DO - Repubblica Dominicana 6
BH - Bahrain 5
CY - Cipro 5
EE - Estonia 5
LK - Sri Lanka 5
LU - Lussemburgo 5
SC - Seychelles 5
BZ - Belize 4
HU - Ungheria 4
NG - Nigeria 4
NO - Norvegia 4
PS - Palestinian Territory 4
SN - Senegal 4
TT - Trinidad e Tobago 4
UG - Uganda 4
AM - Armenia 3
DK - Danimarca 3
PA - Panama 3
RS - Serbia 3
SI - Slovenia 3
SV - El Salvador 3
Totale 38.878
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Città #
Southend 1.851
Ashburn 1.778
Santa Clara 1.447
Singapore 1.429
Fairfield 1.109
Hong Kong 1.026
Woodbridge 992
Chandler 913
Hefei 887
Jacksonville 877
Houston 846
San Jose 791
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
Council Bluffs 536
Helsinki 533
London 526
Seattle 461
Wilmington 443
Beijing 433
Dallas 384
Cambridge 360
Chicago 355
New York 350
Los Angeles 345
Berlin 315
Ho Chi Minh City 279
Modena 259
Seoul 244
Hanoi 230
The Dalles 194
Sofia 177
Milan 174
Eugene 166
Princeton 161
Brussels 159
San Diego 145
Izmir 135
Lauterbourg 131
Des Moines 128
Buffalo 123
Columbus 108
Moscow 99
Salt Lake City 96
Shanghai 89
Dublin 88
São Paulo 83
Amsterdam 74
Orem 67
Toronto 65
Elk Grove Village 62
Frankfurt am Main 59
Fremont 56
Tokyo 53
Tampa 52
Da Nang 51
Redwood City 50
Warsaw 47
Phoenix 46
Boardman 45
Rome 45
Yalova 45
Norwalk 42
Philadelphia 42
Bremen 40
Bologna 38
Guangzhou 38
Kent 36
Shenzhen 35
Mumbai 34
Falls Church 33
Mexico City 33
Haiphong 32
Kunming 31
Naples 28
Rio de Janeiro 28
West Jordan 28
Jakarta 27
Miano 27
Paris 27
San Francisco 27
Turku 27
Augusta 26
Boston 26
Brooklyn 26
Sterling 26
Atlanta 25
Falkenstein 25
Auckland 24
Belo Horizonte 24
Hillsboro 24
Horia 24
Miami 24
Montreal 24
Nanjing 24
Verona 24
Denver 23
Baghdad 22
Totale 26.561
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 1.001
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 839
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 825
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 761
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 654
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 590
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 540
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 510
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 467
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 459
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 454
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 454
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 453
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 440
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 422
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 399
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 391
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 391
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 384
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 377
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 362
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 356
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 352
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 348
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 341
Discovery of a new series of 5-HT1A receptor agonists 340
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 337
Evaluation of stereo and chemical stability of chiral compounds 335
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 327
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 323
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 323
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 315
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 313
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 309
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 307
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 307
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 304
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 301
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 298
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 296
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 285
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 284
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 282
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 281
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 280
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 279
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 273
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 272
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 271
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 269
Insights into the structure of the Human TAAR5 receptor: a computational study 267
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 262
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 260
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 259
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 258
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 257
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 256
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 252
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 249
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 248
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 247
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 246
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 243
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 241
Fallot's tetralogy and squatting position 234
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 233
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 232
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 231
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 226
An unexpected central hypertensive effect of the new imidazoline compound benazoline 225
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 225
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 221
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 221
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 221
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 218
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 215
Effect of the replacement of the o-methoxyphenyl moiety with nitrogen-containing aromatic rings within N-phenyl-piperazine and phenoxy-ethylamine-based 1,3-dioxo/oxathio/dithiolanes as α1 and 5-HT1A receptor ligands 214
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 212
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 211
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 209
Derivati 1,3-Diossanici come Antagonisti Muscarinici 209
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 206
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 205
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 203
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 203
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 203
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 199
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 196
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 196
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 195
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 195
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 194
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 194
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 193
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 191
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 190
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 190
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 189
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 188
IDENTIFICATION OF POTENT 1,3-DIOXOLANE-BASED 5-HT1A RECEPTOR AGONISTS FOR THE TREATMENTS OF CNS DISORDERS AND PAIN 188
Totale 31.101
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Categoria #
all - tutte 134.686
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 134.686
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.289 0 0 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/202611.425 687 570 1.264 1.299 1.559 812 1.214 662 1.065 1.250 551 492
2026/20272.025 374 682 969 0 0 0 0 0 0 0 0 0
Totale 39.161