BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 14.843
EU - Europa 8.996
AS - Asia 6.206
SA - Sud America 925
AF - Africa 75
OC - Oceania 38
Continente sconosciuto - Info sul continente non disponibili 9
Totale 31.092
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Nazione #
US - Stati Uniti d'America 14.661
GB - Regno Unito 2.845
CN - Cina 2.247
SG - Singapore 1.686
SE - Svezia 1.335
IT - Italia 1.239
DE - Germania 1.167
HK - Hong Kong 985
BR - Brasile 773
FI - Finlandia 525
RU - Federazione Russa 476
UA - Ucraina 422
TR - Turchia 280
VN - Vietnam 265
FR - Francia 210
KR - Corea 199
BG - Bulgaria 178
IN - India 172
BE - Belgio 155
CA - Canada 114
NL - Olanda 109
IE - Irlanda 88
RO - Romania 59
ID - Indonesia 58
AR - Argentina 51
JP - Giappone 47
PL - Polonia 45
MX - Messico 41
IR - Iran 39
LT - Lituania 39
BD - Bangladesh 35
IQ - Iraq 29
EC - Ecuador 28
IL - Israele 26
PK - Pakistan 26
NZ - Nuova Zelanda 24
ES - Italia 22
ZA - Sudafrica 20
CL - Cile 16
CO - Colombia 16
VE - Venezuela 15
CH - Svizzera 13
OM - Oman 13
AU - Australia 12
BY - Bielorussia 12
AT - Austria 11
PY - Paraguay 11
SA - Arabia Saudita 11
AE - Emirati Arabi Uniti 10
KE - Kenya 10
TW - Taiwan 9
CI - Costa d'Avorio 8
CZ - Repubblica Ceca 8
EG - Egitto 8
EU - Europa 8
KZ - Kazakistan 8
PT - Portogallo 8
MA - Marocco 7
NP - Nepal 6
PE - Perù 6
TH - Thailandia 6
UZ - Uzbekistan 6
AZ - Azerbaigian 5
DZ - Algeria 5
LU - Lussemburgo 5
MY - Malesia 5
PH - Filippine 5
UY - Uruguay 5
BZ - Belize 4
CR - Costa Rica 4
EE - Estonia 4
LK - Sri Lanka 4
NO - Norvegia 4
AM - Armenia 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
JO - Giordania 3
LB - Libano 3
NG - Nigeria 3
PR - Porto Rico 3
TN - Tunisia 3
UG - Uganda 3
AL - Albania 2
AO - Angola 2
BH - Bahrain 2
BO - Bolivia 2
CU - Cuba 2
DK - Danimarca 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
IS - Islanda 2
KH - Cambogia 2
MM - Myanmar 2
NI - Nicaragua 2
PA - Panama 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
Totale 31.069
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Città #
Southend 1.851
Santa Clara 1.349
Fairfield 1.108
Singapore 999
Woodbridge 992
Hong Kong 959
Ashburn 926
Chandler 913
Hefei 885
Jacksonville 873
Houston 832
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
London 519
Seattle 456
Wilmington 435
Beijing 381
Cambridge 353
Helsinki 336
Dallas 332
New York 278
Chicago 274
Modena 257
Los Angeles 255
Seoul 191
Sofia 177
Eugene 165
Princeton 161
Brussels 154
San Diego 141
Izmir 134
Des Moines 126
Council Bluffs 120
Moscow 98
Ho Chi Minh City 96
Buffalo 93
Salt Lake City 91
The Dalles 90
Dublin 85
Milan 81
Shanghai 79
Amsterdam 68
São Paulo 68
Hanoi 60
Elk Grove Village 57
Fremont 53
Redwood City 50
Tampa 47
Toronto 47
Yalova 45
Norwalk 41
Bremen 40
Boardman 37
Guangzhou 37
Columbus 35
Kent 35
Tokyo 35
Philadelphia 34
Shenzhen 34
Falls Church 33
Bologna 32
Frankfurt am Main 31
Kunming 31
Rome 29
Warsaw 28
West Jordan 28
Turku 27
Jakarta 25
Auckland 24
Augusta 24
Horia 24
Sterling 24
Verona 23
Belo Horizonte 22
Boston 22
Jyväskylä 22
Nanjing 22
San Francisco 22
Sochi 22
Grafing 21
Leawood 21
Rio de Janeiro 21
Phoenix 20
Brooklyn 19
Lancaster 19
Mexico City 18
Montreal 18
Curitiba 17
Jerusalem 17
Mumbai 17
Orem 17
Paris 17
Porto Alegre 17
San Mateo 17
Stockholm 17
Denver 16
Hillsboro 16
Nuremberg 16
Totale 21.769
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 717
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 694
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 608
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 600
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 596
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 515
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 469
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 437
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 408
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 406
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 399
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 394
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 385
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 378
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 364
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 330
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 322
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 320
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 318
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 312
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 307
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 304
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 296
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 290
Evaluation of stereo and chemical stability of chiral compounds 286
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 284
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 284
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 281
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 279
Discovery of a new series of 5-HT1A receptor agonists 276
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 275
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 273
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 251
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 246
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 244
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 244
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 243
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 243
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 238
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 235
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 229
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 229
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 229
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 228
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 224
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 218
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 215
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 214
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 213
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 209
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 208
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 206
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 205
Insights into the structure of the Human TAAR5 receptor: a computational study 203
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 202
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 200
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 200
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 199
An unexpected central hypertensive effect of the new imidazoline compound benazoline 198
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 197
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 197
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 194
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 194
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 193
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 188
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 187
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 184
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 184
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 183
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 178
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 175
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 174
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 174
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 171
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 168
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 168
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 164
Fallot's tetralogy and squatting position 164
Derivati 1,3-Diossanici come Antagonisti Muscarinici 162
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 160
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 160
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 159
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 159
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 158
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 157
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 155
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 155
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 153
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 153
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 153
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 152
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 150
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 150
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 146
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 146
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 146
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 145
Alpha2-Adrenoceptors Profile Modulation anf High Antinociceptove Activity of (S)-)2-[1-(Biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 143
N,N"-(DITHIO-2,1-ETIIANEDIYL)BIS{N'-(PYRROL-2-YLMETI{YL)-1,6-HEXANEDIAMINE}(PYREXTRAMINE), A NEW IRREVERSIBLE a,.ADRENORECEPTOR BLOCKING AGENTTHE TETRAMINE DISULFIDE CLASS 143
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 142
Totale 25.164
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Categoria #
all - tutte 110.956
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 110.956
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.764 0 0 0 0 0 195 315 321 203 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/20265.608 687 570 1.264 1.299 1.559 229 0 0 0 0 0 0
Totale 31.319