A novel class of 1,3-oxathiolane nucleoside analogues have been developed and evaluated as anti-HIV activity in the MT-4 cell line. BHC-371, the adenine derivatives has been found to exhibit significant anti-HIV activity.
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity / Belleau, B.; Brasili, Livio; Chan, L.; DI MARCO, M.; Zacharie, B.; NGUYEN BA, N.; Jenkinson, H. J.; Coates, J. A. V.; Cameron, J. M.. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - STAMPA. - 3:(1993), pp. 1723-1728.
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity.
BRASILI, Livio;
1993
Abstract
A novel class of 1,3-oxathiolane nucleoside analogues have been developed and evaluated as anti-HIV activity in the MT-4 cell line. BHC-371, the adenine derivatives has been found to exhibit significant anti-HIV activity.
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