Transacetalization of acetals with 1,2,4-butanetriol was carried out using cobalt(II) chloride and chlorotrimethylsilane as catalysts. The reaction occurs under mild conditions in acetonitrile with a short reaction times. The synergic effect of the two Lewis acids catalyzes the conversion of butane-1,2,4-triol into (2-alkyl or 2-aryl-1,3-dioxan-4-yl)methanol derivatives with high regiospecificity and diasteroselectivity.
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane / Battisti, UMBERTO MARIA; Sorbi, Claudia; Franchini, Silvia; Tait, Annalisa; Brasili, Livio. - In: SYNTHESIS. - ISSN 0039-7881. - STAMPA. - 46:7(2014), pp. 943-946. [10.1055/s-0033-1340662]
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane
BATTISTI, UMBERTO MARIA;SORBI, Claudia;FRANCHINI, Silvia;TAIT, Annalisa;BRASILI, Livio
2014
Abstract
Transacetalization of acetals with 1,2,4-butanetriol was carried out using cobalt(II) chloride and chlorotrimethylsilane as catalysts. The reaction occurs under mild conditions in acetonitrile with a short reaction times. The synergic effect of the two Lewis acids catalyzes the conversion of butane-1,2,4-triol into (2-alkyl or 2-aryl-1,3-dioxan-4-yl)methanol derivatives with high regiospecificity and diasteroselectivity.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Synthesis_2014.pdf
Accesso riservato
Tipologia:
AAM - Versione dell'autore revisionata e accettata per la pubblicazione
Dimensione
200 kB
Formato
Adobe PDF
|
200 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
