2-(2-Phenylcyclopropyl)imidazoline have been synthetized, the enantiomer separated and tested for their I1 and I2 receptor affinities. It was shown that the two receptor subtypes show reversed stereoselectivity.
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors / W., Q., P., B., M., P., A., C., A., C., M., D., F., G., M., G., F., M., A., P., Brasili, L.. - In: JOURNAL OF MEDICINAL CHEMISTRY. - ISSN 0022-2623. - STAMPA. - 42:(1999), pp. 2737-2740. [10.1021/jm991049m]
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors
BRASILI, Livio
1999
Abstract
2-(2-Phenylcyclopropyl)imidazoline have been synthetized, the enantiomer separated and tested for their I1 and I2 receptor affinities. It was shown that the two receptor subtypes show reversed stereoselectivity.
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