DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 9.889
EU - Europa 4.028
AS - Asia 1.435
SA - Sud America 10
OC - Oceania 6
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.378
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 9.872
GB - Regno Unito 1.967
SE - Svezia 579
SG - Singapore 529
DE - Germania 449
CN - Cina 417
UA - Ucraina 287
TR - Turchia 231
IT - Italia 221
HK - Hong Kong 179
FI - Finlandia 173
RU - Federazione Russa 108
BG - Bulgaria 105
FR - Francia 58
IR - Iran 22
IE - Irlanda 21
IN - India 18
CA - Canada 16
BE - Belgio 14
ID - Indonesia 9
JP - Giappone 8
MY - Malesia 8
CL - Cile 7
NL - Olanda 7
CZ - Repubblica Ceca 6
PL - Polonia 6
CH - Svizzera 5
BD - Bangladesh 4
ES - Italia 4
LT - Lituania 4
AU - Australia 3
EU - Europa 3
NZ - Nuova Zelanda 3
RO - Romania 3
VN - Vietnam 3
ZA - Sudafrica 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AT - Austria 2
DK - Danimarca 2
MK - Macedonia 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CM - Camerun 1
EC - Ecuador 1
EE - Estonia 1
EG - Egitto 1
GR - Grecia 1
IQ - Iraq 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MD - Moldavia 1
MX - Messico 1
NO - Norvegia 1
PE - Perù 1
PK - Pakistan 1
SI - Slovenia 1
Totale 15.378
Salva come PNG Salva come JPEG
Città #
Southend 1.691
Fairfield 1.184
Santa Clara 1.115
Woodbridge 913
Houston 718
Jacksonville 663
Chandler 660
Ashburn 627
Ann Arbor 488
Seattle 445
Dearborn 442
Wilmington 432
Singapore 409
Cambridge 388
Nyköping 288
Hong Kong 176
Izmir 144
Grafing 122
Beijing 120
Des Moines 120
San Diego 117
Princeton 108
Sofia 104
Modena 103
Eugene 102
Helsinki 73
Chicago 67
Bremen 61
New York 61
Moscow 44
Falls Church 35
London 35
Redwood City 33
San Mateo 24
Norwalk 22
Dublin 21
Fremont 20
Shanghai 20
Milan 19
Boardman 18
Verona 18
Philadelphia 16
Kunming 15
Brussels 14
Hefei 13
Nanjing 13
Auburn Hills 12
Los Angeles 12
Leawood 11
Ardabil 10
Augusta 10
Indiana 10
Kilburn 10
Monmouth Junction 10
Guangzhou 9
Munich 9
Saint Petersburg 9
Hounslow 8
Jakarta 8
Jinan 8
San Francisco 8
Acton 7
Fuzhou 7
Shenyang 7
Toronto 7
Chengdu 6
Chiswick 6
Prescot 6
Wuhan 6
Dallas 5
Kraków 5
Napoli 5
Ottawa 5
Parma 5
Zurich 5
Bedok 4
Bologna 4
Brno 4
Crosia 4
Frankfurt am Main 4
Jinhua 4
Mountain View 4
Osaka 4
Phoenix 4
Sacramento 4
Wenzhou 4
Alexandria 3
Andover 3
Falkenstein 3
Paris 3
Pune 3
Reggio Nell'emilia 3
Samara 3
Tokyo 3
Amsterdam 2
Auckland 2
Baotou 2
Cesena 2
Ceska 2
Council Bluffs 2
Totale 12.627
Salva come PNG Salva come JPEG
Nome #
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 216
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 213
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 213
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 210
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 204
Computational modeling of intramolecular and intermolecular communication in GPCRs 202
Computational simulations of stem-cell factor c-Kit receptor interaction 201
Theoretical study on the electrostatically driven step of receptor-G protein recognition 197
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 197
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 196
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 194
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 194
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 194
Theoretical investigation of IL-6 multiprotein receptor assembly 193
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 192
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 191
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 191
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 190
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 189
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 186
Structure-function relationships of the alpha(1b)-adrenergic receptor 186
Prototropic molecular forms and theoretical descriptors in QSAR analysis 186
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 185
The ad hoc supermolecule approach to receptor ligand design 184
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 184
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 183
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 181
Multiscale quantum chemical approaches to QSAR modeling and drug design 180
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 180
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 178
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 177
Ligand-Receptor Communication and Drug Design 177
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 167
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 167
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 166
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 166
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 166
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 165
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 164
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 162
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 161
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 161
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 160
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 158
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 157
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 156
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 155
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 155
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 154
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 152
Seeking for binding determinants of the prion protein to human plasminogen 150
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 149
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 149
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 148
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 147
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 146
Molecular dynamics of guest radicals in urea inclusion compounds 145
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 144
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 144
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 144
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 144
The heuristic-direct approach to quantitative structure-activity relationship analysis 143
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 143
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 142
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 142
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 142
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 141
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 141
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 141
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 140
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 139
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 139
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 138
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 136
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 134
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 132
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 131
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 129
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 123
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 123
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 121
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 120
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 117
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 116
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 115
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 113
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 112
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 112
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 110
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 101
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 98
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 96
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 93
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 92
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 90
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 88
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 85
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 84
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 83
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 75
Totale 15.266
Salva come PNG Salva come JPEG
Categoria #
all - tutte 64.281
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.281
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.015 0 0 0 0 0 431 513 356 315 85 160 155
2020/20212.138 220 101 192 196 207 106 177 263 97 305 169 105
2021/20221.919 65 287 200 138 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20251.928 283 57 56 255 783 494 0 0 0 0 0 0
Totale 15.448