DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 14.041
AS - Asia 6.496
EU - Europa 5.182
SA - Sud America 801
AF - Africa 135
Continente sconosciuto - Info sul continente non disponibili 77
OC - Oceania 8
Totale 26.740
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Nazione #
US - Stati Uniti d'America 13.850
GB - Regno Unito 2.263
SG - Singapore 2.095
CN - Cina 1.994
HK - Hong Kong 717
BR - Brasile 623
SE - Svezia 616
VN - Vietnam 609
DE - Germania 561
IT - Italia 418
UA - Ucraina 313
FI - Finlandia 262
KR - Corea 251
TR - Turchia 248
RU - Federazione Russa 221
FR - Francia 177
BD - Bangladesh 146
BG - Bulgaria 111
CA - Canada 108
IN - India 107
AR - Argentina 67
IQ - Iraq 45
MA - Marocco 41
MX - Messico 41
ID - Indonesia 40
ZA - Sudafrica 40
JP - Giappone 37
EC - Ecuador 30
NL - Olanda 30
PL - Polonia 30
AE - Emirati Arabi Uniti 26
IE - Irlanda 24
CL - Cile 23
ES - Italia 23
IR - Iran 23
PK - Pakistan 23
BE - Belgio 20
LT - Lituania 18
MY - Malesia 18
CO - Colombia 15
SA - Arabia Saudita 15
JO - Giordania 14
PY - Paraguay 14
VE - Venezuela 14
PH - Filippine 13
DZ - Algeria 12
AT - Austria 11
KE - Kenya 10
TN - Tunisia 10
CH - Svizzera 9
CZ - Repubblica Ceca 9
KZ - Kazakistan 9
EG - Egitto 8
HN - Honduras 8
PE - Perù 8
RO - Romania 8
UZ - Uzbekistan 8
AL - Albania 7
EE - Estonia 7
JM - Giamaica 7
PT - Portogallo 6
AU - Australia 5
AZ - Azerbaigian 5
CR - Costa Rica 5
DO - Repubblica Dominicana 5
HU - Ungheria 5
IL - Israele 5
NP - Nepal 5
TW - Taiwan 5
UY - Uruguay 5
BY - Bielorussia 4
GT - Guatemala 4
LB - Libano 4
PA - Panama 4
PS - Palestinian Territory 4
QA - Qatar 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
BH - Bahrain 3
BN - Brunei Darussalam 3
DK - Danimarca 3
ET - Etiopia 3
EU - Europa 3
GR - Grecia 3
HR - Croazia 3
KG - Kirghizistan 3
MK - Macedonia 3
NZ - Nuova Zelanda 3
OM - Oman 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AO - Angola 2
BO - Bolivia 2
GE - Georgia 2
LK - Sri Lanka 2
LU - Lussemburgo 2
LV - Lettonia 2
MD - Moldavia 2
PR - Porto Rico 2
Totale 26.644
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Città #
Southend 1.691
Ashburn 1.336
Singapore 1.290
Santa Clara 1.206
Fairfield 1.184
Hefei 956
Woodbridge 914
Houston 734
Hong Kong 703
Jacksonville 667
Chandler 660
Ann Arbor 488
San Jose 474
Wilmington 455
Seattle 453
Dearborn 442
Cambridge 391
Chicago 375
Nyköping 288
Council Bluffs 282
Beijing 272
London 264
Los Angeles 256
Seoul 244
Ho Chi Minh City 184
Helsinki 154
Hanoi 150
The Dalles 146
Izmir 145
New York 132
Des Moines 122
Grafing 122
San Diego 119
Buffalo 111
Princeton 108
Modena 106
Sofia 105
Eugene 103
Salt Lake City 94
Lauterbourg 88
Milan 71
Moscow 64
Bremen 61
Shanghai 57
São Paulo 53
Elk Grove Village 48
Columbus 45
Frankfurt am Main 44
Dallas 43
Tampa 42
Falls Church 35
Munich 34
Redwood City 33
Tokyo 32
Philadelphia 31
Falkenstein 30
Guangzhou 29
Kent 27
Casablanca 26
Orem 25
San Mateo 25
Toronto 25
Dublin 23
Da Nang 22
Montreal 22
Norwalk 22
Rio de Janeiro 22
Atlanta 21
Fremont 21
Haiphong 21
Mexico City 21
Verona 21
Lancaster 20
San Francisco 20
Boardman 19
Brussels 19
Jakarta 19
Ottawa 19
Phoenix 19
Baghdad 18
Brooklyn 18
Johannesburg 18
Kunming 18
Miano 17
Sterling 17
Warsaw 17
Detroit 16
Miami 16
Denver 15
Nanjing 15
Stockholm 15
Chennai 14
Hải Dương 14
Amsterdam 13
Brasília 13
Charlotte 13
Poplar 13
Auburn Hills 12
Curitiba 12
Manchester 12
Totale 19.561
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Nome #
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 434
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 427
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 424
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 419
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 387
Computational modeling of intramolecular and intermolecular communication in GPCRs 378
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 364
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 356
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 348
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 347
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 346
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 335
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 331
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 326
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 319
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 318
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 317
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 315
Structure-function relationships of the alpha(1b)-adrenergic receptor 314
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 312
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 312
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 310
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 310
Computational simulations of stem-cell factor c-Kit receptor interaction 305
Theoretical investigation of IL-6 multiprotein receptor assembly 294
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 293
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 293
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 290
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 287
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 285
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 285
The ad hoc supermolecule approach to receptor ligand design 284
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 284
Prototropic molecular forms and theoretical descriptors in QSAR analysis 282
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 281
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 279
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 277
Theoretical study on the electrostatically driven step of receptor-G protein recognition 276
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 276
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 270
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 270
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 270
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 268
Molecular dynamics of guest radicals in urea inclusion compounds 267
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 266
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 266
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 263
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 262
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 260
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 260
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 257
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 256
Multiscale quantum chemical approaches to QSAR modeling and drug design 255
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 252
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 250
Ligand-Receptor Communication and Drug Design 250
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 249
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 246
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 245
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 244
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 244
Seeking for binding determinants of the prion protein to human plasminogen 241
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 241
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 239
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 235
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 231
The heuristic-direct approach to quantitative structure-activity relationship analysis 230
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 230
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 228
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 228
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 227
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 227
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 225
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 224
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 223
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 218
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 216
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 215
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 212
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 211
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 211
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 209
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 199
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 194
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 193
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 192
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 187
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 187
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 187
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 186
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 185
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 179
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 171
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 171
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 171
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 165
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 158
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 158
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 157
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 148
Totale 26.199
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Categoria #
all - tutte 101.781
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.781
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.854 0 287 200 138 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20254.588 283 57 56 255 783 592 333 296 406 214 681 632
2025/20267.942 603 380 810 1.079 1.206 694 789 383 823 605 358 212
2026/2027690 266 424 0 0 0 0 0 0 0 0 0 0
Totale 26.740