DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 11.896
AS - Asia 5.005
EU - Europa 4.711
SA - Sud America 606
AF - Africa 82
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 6
Totale 22.312
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Nazione #
US - Stati Uniti d'America 11.802
GB - Regno Unito 2.237
CN - Cina 1.832
SG - Singapore 1.633
HK - Hong Kong 660
SE - Svezia 614
DE - Germania 532
BR - Brasile 513
UA - Ucraina 302
IT - Italia 251
TR - Turchia 238
KR - Corea 230
RU - Federazione Russa 216
FI - Finlandia 200
VN - Vietnam 173
BG - Bulgaria 108
FR - Francia 79
CA - Canada 64
IN - India 50
MA - Marocco 35
AR - Argentina 30
JP - Giappone 26
PL - Polonia 26
ZA - Sudafrica 25
ID - Indonesia 24
BD - Bangladesh 23
IE - Irlanda 23
IR - Iran 23
NL - Olanda 23
EC - Ecuador 20
MX - Messico 20
BE - Belgio 19
IQ - Iraq 17
LT - Lituania 17
CL - Cile 15
ES - Italia 11
MY - Malesia 11
AE - Emirati Arabi Uniti 10
PY - Paraguay 10
CZ - Repubblica Ceca 8
PK - Pakistan 8
CH - Svizzera 7
AT - Austria 6
KZ - Kazakistan 6
VE - Venezuela 6
CO - Colombia 5
JO - Giordania 5
RO - Romania 5
DZ - Algeria 4
KE - Kenya 4
NP - Nepal 4
PE - Perù 4
SA - Arabia Saudita 4
TN - Tunisia 4
AL - Albania 3
AU - Australia 3
AZ - Azerbaigian 3
BN - Brunei Darussalam 3
DK - Danimarca 3
ET - Etiopia 3
EU - Europa 3
HU - Ungheria 3
NZ - Nuova Zelanda 3
UY - Uruguay 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
EE - Estonia 2
EG - Egitto 2
GE - Georgia 2
HR - Croazia 2
IL - Israele 2
LB - Libano 2
LV - Lettonia 2
MK - Macedonia 2
PH - Filippine 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
AD - Andorra 1
BB - Barbados 1
CG - Congo 1
CM - Camerun 1
CR - Costa Rica 1
DM - Dominica 1
GM - Gambi 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
IS - Islanda 1
JM - Giamaica 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PS - Palestinian Territory 1
Totale 22.305
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Città #
Southend 1.691
Fairfield 1.184
Santa Clara 1.138
Singapore 979
Hefei 955
Woodbridge 913
Ashburn 845
Houston 726
Jacksonville 664
Chandler 660
Hong Kong 656
Ann Arbor 488
Wilmington 454
Seattle 450
Dearborn 442
Cambridge 388
Nyköping 288
London 261
Chicago 254
Beijing 234
Seoul 225
Los Angeles 211
Izmir 145
Grafing 122
Des Moines 120
San Diego 118
Princeton 108
Modena 105
New York 104
Sofia 104
Buffalo 103
Eugene 102
Council Bluffs 97
Helsinki 92
Salt Lake City 76
The Dalles 68
Ho Chi Minh City 66
Bremen 61
Moscow 61
Shanghai 52
São Paulo 45
Elk Grove Village 42
Hanoi 38
Tampa 38
Falls Church 35
Munich 34
Redwood City 33
Columbus 32
Dallas 32
Frankfurt am Main 32
Milan 29
Kent 27
Casablanca 26
Guangzhou 25
Philadelphia 25
San Mateo 25
Dublin 22
Norwalk 22
Fremont 21
Tokyo 21
Toronto 21
Brussels 19
Lancaster 19
San Francisco 19
Boardman 18
Falkenstein 18
Kunming 18
Verona 18
Jakarta 17
Rio de Janeiro 17
Ottawa 16
Sterling 16
Warsaw 16
Nanjing 15
Brooklyn 14
Montreal 14
Stockholm 14
Mexico City 13
Poplar 13
Atlanta 12
Auburn Hills 12
Johannesburg 12
Belo Horizonte 11
Brasília 11
Denver 11
Detroit 11
Leawood 11
Phoenix 11
Ardabil 10
Augusta 10
Dulles 10
Indiana 10
Kilburn 10
Monmouth Junction 10
Orem 10
Quito 10
Shenyang 10
Curitiba 9
Miami 9
Saint Petersburg 9
Totale 16.948
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Nome #
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 397
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 389
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 378
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 364
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 328
Computational modeling of intramolecular and intermolecular communication in GPCRs 313
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 304
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 297
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 291
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 287
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 284
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 283
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 280
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 280
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 271
Computational simulations of stem-cell factor c-Kit receptor interaction 267
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 266
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 262
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 260
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 254
Prototropic molecular forms and theoretical descriptors in QSAR analysis 253
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 253
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 252
Structure-function relationships of the alpha(1b)-adrenergic receptor 251
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 250
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 249
The ad hoc supermolecule approach to receptor ligand design 248
Theoretical investigation of IL-6 multiprotein receptor assembly 245
Theoretical study on the electrostatically driven step of receptor-G protein recognition 245
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 242
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 239
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 239
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 236
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 236
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 236
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 235
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 234
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 231
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 229
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 229
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 228
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 224
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 223
Multiscale quantum chemical approaches to QSAR modeling and drug design 223
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 221
Molecular dynamics of guest radicals in urea inclusion compounds 220
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 219
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 218
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 218
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 217
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 217
Ligand-Receptor Communication and Drug Design 217
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 215
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 212
Seeking for binding determinants of the prion protein to human plasminogen 212
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 211
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 210
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 208
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 207
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 207
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 206
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 204
The heuristic-direct approach to quantitative structure-activity relationship analysis 203
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 202
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 199
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 198
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 196
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 195
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 194
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 192
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 189
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 188
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 188
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 186
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 184
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 181
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 179
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 176
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 176
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 172
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 170
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 167
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 167
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 166
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 165
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 165
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 156
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 153
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 153
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 148
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 148
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 146
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 139
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 138
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 137
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 137
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 135
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 128
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 125
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 118
Totale 21.983
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Categoria #
all - tutte 87.226
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.226
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.222 0 0 0 0 0 106 177 263 97 305 169 105
2021/20221.919 65 287 200 138 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20254.588 283 57 56 255 783 592 333 296 406 214 681 632
2025/20264.275 603 380 810 1.079 1.206 197 0 0 0 0 0 0
Totale 22.383