DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 15.770
AS - Asia 6.525
EU - Europa 5.256
SA - Sud America 813
AF - Africa 141
Continente sconosciuto - Info sul continente non disponibili 82
OC - Oceania 8
Totale 28.595
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Nazione #
US - Stati Uniti d'America 15.484
GB - Regno Unito 2.280
SG - Singapore 2.100
CN - Cina 1.995
HK - Hong Kong 718
BR - Brasile 633
SE - Svezia 616
VN - Vietnam 610
DE - Germania 566
IT - Italia 455
UA - Ucraina 313
FI - Finlandia 262
KR - Corea 251
TR - Turchia 250
RU - Federazione Russa 228
FR - Francia 180
BD - Bangladesh 149
CA - Canada 148
BG - Bulgaria 111
IN - India 108
AR - Argentina 68
IQ - Iraq 45
MX - Messico 44
MA - Marocco 41
ZA - Sudafrica 41
ID - Indonesia 40
JP - Giappone 38
PL - Polonia 31
EC - Ecuador 30
NL - Olanda 30
AE - Emirati Arabi Uniti 27
ES - Italia 24
IE - Irlanda 24
CL - Cile 23
IR - Iran 23
PK - Pakistan 23
BE - Belgio 20
MY - Malesia 19
CR - Costa Rica 18
LT - Lituania 18
CO - Colombia 16
SA - Arabia Saudita 16
IL - Israele 14
JO - Giordania 14
PY - Paraguay 14
VE - Venezuela 14
PH - Filippine 13
DZ - Algeria 12
JM - Giamaica 12
AT - Austria 11
HN - Honduras 11
CH - Svizzera 10
KE - Kenya 10
TN - Tunisia 10
CZ - Repubblica Ceca 9
KZ - Kazakistan 9
UZ - Uzbekistan 9
EG - Egitto 8
NI - Nicaragua 8
PE - Perù 8
RO - Romania 8
AL - Albania 7
EE - Estonia 7
GT - Guatemala 7
TT - Trinidad e Tobago 7
NP - Nepal 6
PR - Porto Rico 6
PT - Portogallo 6
AU - Australia 5
AZ - Azerbaigian 5
CW - ???statistics.table.value.countryCode.CW??? 5
DK - Danimarca 5
DO - Repubblica Dominicana 5
HU - Ungheria 5
TW - Taiwan 5
UY - Uruguay 5
BB - Barbados 4
BY - Bielorussia 4
LB - Libano 4
PA - Panama 4
PS - Palestinian Territory 4
QA - Qatar 4
SC - Seychelles 4
SK - Slovacchia (Repubblica Slovacca) 4
SV - El Salvador 4
TH - Thailandia 4
BH - Bahrain 3
BN - Brunei Darussalam 3
ET - Etiopia 3
EU - Europa 3
GR - Grecia 3
HR - Croazia 3
KG - Kirghizistan 3
MK - Macedonia 3
NZ - Nuova Zelanda 3
OM - Oman 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AO - Angola 2
Totale 28.485
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Città #
Ashburn 1.995
Southend 1.691
Singapore 1.290
Santa Clara 1.218
Fairfield 1.184
Hefei 956
Woodbridge 914
Houston 738
Hong Kong 704
Jacksonville 670
Chandler 660
San Jose 602
Ann Arbor 488
Wilmington 457
Seattle 454
Dearborn 442
Council Bluffs 407
Cambridge 401
Chicago 388
Nyköping 288
Los Angeles 285
Beijing 272
London 266
Seoul 244
Ho Chi Minh City 184
The Dalles 158
Helsinki 154
Hanoi 150
Izmir 145
New York 140
San Diego 127
Des Moines 122
Grafing 122
Buffalo 119
Princeton 112
Modena 106
Sofia 105
Eugene 103
Salt Lake City 95
Lauterbourg 88
Milan 79
Moscow 68
São Paulo 62
Bremen 61
Norfolk 57
Shanghai 57
Dallas 51
Columbus 48
Elk Grove Village 48
Frankfurt am Main 44
Tampa 44
Phoenix 42
Toronto 36
Falls Church 35
Munich 34
Redwood City 33
Tokyo 33
Philadelphia 32
Atlanta 30
Falkenstein 30
Guangzhou 29
Kent 27
Casablanca 26
San Francisco 26
Montreal 25
Orem 25
San Mateo 25
Washington 25
Dublin 23
Da Nang 22
Lancaster 22
Mexico City 22
North Bergen 22
Norwalk 22
Rio de Janeiro 22
Fremont 21
Haiphong 21
Verona 21
Brooklyn 20
Ottawa 20
Boardman 19
Brussels 19
Jakarta 19
Baghdad 18
Detroit 18
Johannesburg 18
Kunming 18
Warsaw 18
Charlotte 17
Denver 17
Miano 17
Sterling 17
Miami 16
Nanjing 15
Stockholm 15
Chennai 14
Hải Dương 14
Amsterdam 13
Brasília 13
Manchester 13
Totale 20.762
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Nome #
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 449
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 448
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 440
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 433
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 401
Computational modeling of intramolecular and intermolecular communication in GPCRs 392
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 391
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 368
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 368
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 365
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 363
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 362
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 349
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 348
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 344
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 342
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 340
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 332
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 332
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 331
Structure-function relationships of the alpha(1b)-adrenergic receptor 329
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 328
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 327
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 321
Computational simulations of stem-cell factor c-Kit receptor interaction 316
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 315
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 313
Theoretical investigation of IL-6 multiprotein receptor assembly 309
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 308
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 307
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 306
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 305
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 301
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 300
Theoretical study on the electrostatically driven step of receptor-G protein recognition 300
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 299
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 298
The ad hoc supermolecule approach to receptor ligand design 297
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 294
Prototropic molecular forms and theoretical descriptors in QSAR analysis 294
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 289
Molecular dynamics of guest radicals in urea inclusion compounds 287
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 286
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 286
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 284
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 283
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 281
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 278
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 277
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 275
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 275
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 273
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 272
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 269
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 266
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 266
Ligand-Receptor Communication and Drug Design 263
Multiscale quantum chemical approaches to QSAR modeling and drug design 262
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 257
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 256
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 254
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 253
Seeking for binding determinants of the prion protein to human plasminogen 252
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 252
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 248
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 244
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 243
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 243
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 243
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 242
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 242
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 241
The heuristic-direct approach to quantitative structure-activity relationship analysis 240
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 240
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 240
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 237
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 237
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 235
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 233
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 227
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 226
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 223
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 222
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 217
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 216
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 216
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 212
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 208
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 208
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 204
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 203
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 203
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 200
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 196
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 195
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 187
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 176
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 174
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 168
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 164
Totale 28.014
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Categoria #
all - tutte 107.686
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 107.686
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.229 0 0 0 0 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20254.588 283 57 56 255 783 592 333 296 406 214 681 632
2025/20267.942 603 380 810 1.079 1.206 694 789 383 823 605 358 212
2026/20272.545 266 448 631 1.045 155 0 0 0 0 0 0 0
Totale 28.595