DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 12.372
AS - Asia 5.179
EU - Europa 4.741
SA - Sud America 630
AF - Africa 87
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 6
Totale 23.021
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Nazione #
US - Stati Uniti d'America 12.275
GB - Regno Unito 2.238
CN - Cina 1.869
SG - Singapore 1.738
HK - Hong Kong 663
SE - Svezia 615
DE - Germania 533
BR - Brasile 532
UA - Ucraina 307
IT - Italia 252
TR - Turchia 239
KR - Corea 230
RU - Federazione Russa 216
FI - Finlandia 212
VN - Vietnam 182
BG - Bulgaria 108
FR - Francia 84
CA - Canada 66
IN - India 52
MA - Marocco 36
AR - Argentina 31
JP - Giappone 28
BD - Bangladesh 26
PL - Polonia 26
ID - Indonesia 25
ZA - Sudafrica 25
IE - Irlanda 23
IR - Iran 23
NL - Olanda 23
EC - Ecuador 21
IQ - Iraq 20
MX - Messico 20
BE - Belgio 19
LT - Lituania 18
CL - Cile 15
AE - Emirati Arabi Uniti 12
ES - Italia 12
MY - Malesia 11
PY - Paraguay 10
CZ - Repubblica Ceca 8
PK - Pakistan 8
AT - Austria 7
CH - Svizzera 7
CO - Colombia 7
JO - Giordania 7
VE - Venezuela 7
KZ - Kazakistan 6
DZ - Algeria 5
KE - Kenya 5
RO - Romania 5
SA - Arabia Saudita 5
NP - Nepal 4
PE - Perù 4
TN - Tunisia 4
AL - Albania 3
AU - Australia 3
AZ - Azerbaigian 3
BN - Brunei Darussalam 3
DK - Danimarca 3
EE - Estonia 3
ET - Etiopia 3
EU - Europa 3
HU - Ungheria 3
NZ - Nuova Zelanda 3
PH - Filippine 3
UY - Uruguay 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AO - Angola 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GE - Georgia 2
HR - Croazia 2
IL - Israele 2
LB - Libano 2
LV - Lettonia 2
MK - Macedonia 2
PA - Panama 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
TW - Taiwan 2
AD - Andorra 1
BB - Barbados 1
CG - Congo 1
CM - Camerun 1
CR - Costa Rica 1
DM - Dominica 1
GM - Gambi 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
IS - Islanda 1
JM - Giamaica 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
Totale 23.013
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Città #
Southend 1.691
Fairfield 1.184
Santa Clara 1.138
Singapore 1.057
Hefei 956
Woodbridge 913
Ashburn 887
Houston 728
Jacksonville 666
Chandler 660
Hong Kong 659
Ann Arbor 488
Wilmington 454
Seattle 450
Dearborn 442
Cambridge 388
Chicago 298
Nyköping 288
London 262
Beijing 236
Los Angeles 231
Seoul 225
Izmir 145
San Jose 139
Grafing 122
Des Moines 120
San Diego 118
New York 110
Princeton 108
Modena 105
Buffalo 104
Helsinki 104
Sofia 104
Eugene 103
The Dalles 102
Council Bluffs 101
Salt Lake City 94
Ho Chi Minh City 70
Bremen 61
Moscow 61
Shanghai 52
Elk Grove Village 48
São Paulo 47
Tampa 42
Hanoi 38
Falls Church 35
Dallas 34
Munich 34
Columbus 33
Redwood City 33
Frankfurt am Main 32
Milan 29
Kent 27
Casablanca 26
Guangzhou 26
Philadelphia 25
San Mateo 25
Tokyo 23
Dublin 22
Norwalk 22
Fremont 21
Toronto 21
Brussels 19
Lancaster 19
San Francisco 19
Boardman 18
Falkenstein 18
Jakarta 18
Kunming 18
Rio de Janeiro 18
Verona 18
Atlanta 17
Ottawa 17
Sterling 17
Montreal 16
Warsaw 16
Nanjing 15
Stockholm 15
Brooklyn 14
Phoenix 14
Detroit 13
Mexico City 13
Orem 13
Poplar 13
Auburn Hills 12
Brasília 12
Denver 12
Johannesburg 12
Belo Horizonte 11
Dulles 11
Leawood 11
Miami 11
Ardabil 10
Augusta 10
Curitiba 10
Indiana 10
Kilburn 10
Monmouth Junction 10
Quito 10
Shenyang 10
Totale 17.397
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Nome #
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 404
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 402
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 387
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 376
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 334
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 324
Computational modeling of intramolecular and intermolecular communication in GPCRs 321
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 313
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 304
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 301
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 295
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 291
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 290
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 286
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 286
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 278
Computational simulations of stem-cell factor c-Kit receptor interaction 276
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 273
Structure-function relationships of the alpha(1b)-adrenergic receptor 268
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 268
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 264
Prototropic molecular forms and theoretical descriptors in QSAR analysis 262
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 262
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 261
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 260
Theoretical study on the electrostatically driven step of receptor-G protein recognition 257
Theoretical investigation of IL-6 multiprotein receptor assembly 255
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 254
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 252
The ad hoc supermolecule approach to receptor ligand design 250
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 250
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 248
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 247
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 246
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 243
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 243
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 241
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 239
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 238
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 236
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 233
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 232
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 228
Molecular dynamics of guest radicals in urea inclusion compounds 227
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 227
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 227
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 227
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 225
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 225
Multiscale quantum chemical approaches to QSAR modeling and drug design 225
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 223
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 222
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 221
Seeking for binding determinants of the prion protein to human plasminogen 219
Ligand-Receptor Communication and Drug Design 219
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 218
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 215
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 214
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 214
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 211
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 210
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 209
The heuristic-direct approach to quantitative structure-activity relationship analysis 209
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 205
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 205
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 203
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 201
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 200
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 200
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 200
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 198
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 196
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 190
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 190
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 189
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 189
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 188
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 182
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 181
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 176
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 173
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 170
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 170
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 170
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 167
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 166
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 156
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 156
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 155
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 153
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 149
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 148
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 146
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 142
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 142
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 141
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 138
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 129
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 128
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 121
Totale 22.678
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Categoria #
all - tutte 88.991
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 88.991
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.116 0 0 0 0 0 0 177 263 97 305 169 105
2021/20221.919 65 287 200 138 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20254.588 283 57 56 255 783 592 333 296 406 214 681 632
2025/20264.984 603 380 810 1.079 1.206 694 212 0 0 0 0 0
Totale 23.092