DE BENEDETTI, Pier Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 13.437
AS - Asia 6.427
EU - Europa 5.137
SA - Sud America 788
AF - Africa 135
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 6
Totale 25.938
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Nazione #
US - Stati Uniti d'America 13.281
GB - Regno Unito 2.261
SG - Singapore 2.068
CN - Cina 1.978
HK - Hong Kong 712
BR - Brasile 618
SE - Svezia 616
VN - Vietnam 609
DE - Germania 560
IT - Italia 384
UA - Ucraina 313
FI - Finlandia 261
KR - Corea 251
TR - Turchia 246
RU - Federazione Russa 220
FR - Francia 177
BD - Bangladesh 134
BG - Bulgaria 111
IN - India 107
CA - Canada 90
AR - Argentina 63
IQ - Iraq 45
MA - Marocco 41
MX - Messico 40
ZA - Sudafrica 40
ID - Indonesia 38
JP - Giappone 37
PL - Polonia 30
EC - Ecuador 29
NL - Olanda 29
AE - Emirati Arabi Uniti 25
IE - Irlanda 24
CL - Cile 23
IR - Iran 23
PK - Pakistan 23
BE - Belgio 20
ES - Italia 20
LT - Lituania 18
MY - Malesia 17
CO - Colombia 14
JO - Giordania 14
PY - Paraguay 14
SA - Arabia Saudita 14
VE - Venezuela 13
DZ - Algeria 12
PH - Filippine 12
AT - Austria 11
KE - Kenya 10
TN - Tunisia 10
CZ - Repubblica Ceca 9
EG - Egitto 8
KZ - Kazakistan 8
RO - Romania 8
UZ - Uzbekistan 8
AL - Albania 7
CH - Svizzera 7
EE - Estonia 7
PE - Perù 7
PT - Portogallo 6
AU - Australia 5
AZ - Azerbaigian 5
DO - Repubblica Dominicana 5
HU - Ungheria 5
IL - Israele 5
NP - Nepal 5
TW - Taiwan 5
UY - Uruguay 5
BY - Bielorussia 4
JM - Giamaica 4
LB - Libano 4
PA - Panama 4
PS - Palestinian Territory 4
QA - Qatar 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
BH - Bahrain 3
BN - Brunei Darussalam 3
CR - Costa Rica 3
DK - Danimarca 3
ET - Etiopia 3
EU - Europa 3
GR - Grecia 3
HN - Honduras 3
HR - Croazia 3
KG - Kirghizistan 3
MK - Macedonia 3
NZ - Nuova Zelanda 3
OM - Oman 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AO - Angola 2
BO - Bolivia 2
GE - Georgia 2
LK - Sri Lanka 2
LU - Lussemburgo 2
LV - Lettonia 2
MD - Moldavia 2
RS - Serbia 2
SI - Slovenia 2
Totale 25.917
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Città #
Southend 1.691
Singapore 1.278
Fairfield 1.184
Santa Clara 1.182
Ashburn 1.172
Hefei 956
Woodbridge 913
Houston 730
Hong Kong 698
Jacksonville 666
Chandler 660
Ann Arbor 488
Wilmington 454
Seattle 451
Dearborn 442
Cambridge 391
San Jose 380
Chicago 369
Nyköping 288
Beijing 269
London 264
Los Angeles 254
Seoul 244
Ho Chi Minh City 184
Council Bluffs 181
Helsinki 153
Hanoi 150
Izmir 145
The Dalles 145
New York 126
Grafing 122
Des Moines 121
San Diego 118
Buffalo 108
Princeton 108
Modena 106
Sofia 105
Eugene 103
Salt Lake City 94
Lauterbourg 88
Milan 64
Bremen 61
Moscow 61
Shanghai 56
São Paulo 53
Elk Grove Village 48
Frankfurt am Main 43
Dallas 42
Tampa 42
Columbus 36
Falls Church 35
Munich 34
Redwood City 33
Tokyo 32
Falkenstein 30
Guangzhou 28
Philadelphia 28
Kent 27
Casablanca 26
Orem 25
San Mateo 25
Toronto 25
Dublin 23
Da Nang 22
Norwalk 22
Rio de Janeiro 22
Fremont 21
Haiphong 21
Lancaster 20
Mexico City 20
San Francisco 20
Verona 20
Atlanta 19
Boardman 19
Brussels 19
Jakarta 19
Montreal 19
Baghdad 18
Johannesburg 18
Kunming 18
Ottawa 18
Brooklyn 17
Miano 17
Sterling 17
Warsaw 17
Phoenix 16
Nanjing 15
Stockholm 15
Chennai 14
Denver 14
Detroit 14
Hải Dương 14
Amsterdam 13
Brasília 13
Poplar 13
Auburn Hills 12
Miami 12
Quito 12
Amman 11
Augusta 11
Totale 19.080
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Nome #
Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR 429
Computational modeling approaches to Structure-Function Analysis of G Protein-Coupled Receptors 421
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor 416
Mechanisms of inter- and intramolecular communication in GPCRs and G proteins 412
Molecular dynamics simulations of the ligand-induced chemical information transfer in the 5-HT1A receptor 377
Computational modeling of intramolecular and intermolecular communication in GPCRs 368
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations 352
Comparative molecular dynamics study of the seven-helix bundle arrangement of G-protein coupled receptors 350
A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites 341
A MOLECULAR-DYNAMICS SIMULATION OF SEQUENCE-DIRECTED RECOGNITION PEPTIDES INTERACTING WITH BIGENDOTHELIN 340
Activation mechanism of human oxytocin receptor: A combined study of experimental and computer-simulated mutagenesis 338
CORRELATION AND MULTIVARIATE ANALYSES OF SPECTROSCOPIC AND DIHYDROPTEROATE SYNTHASE INHIBITORY ACTIVITY DATA IN 4-AMINOARYL (MULTISUBSTITUTED ARYL) SULFONES 323
Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations 323
A THEORETICAL-STUDY OF THE STRUCTURE OF BIG ENDOTHELIN 314
Computational modeling approaches to quantitative structure–binding kinetics relationships in drug discovery 313
Alpha 1-adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure-affinity relationships 310
Quantitative Structure-Activity Relationships in Dihydropteroate Synthase Inhibition by Multisubstituted Sulfones. Design and Synthesis of Some New Derivatives with Improved Potency. 309
Probing fragment complementation by rigid-body docking: In silico reconstitution of calbindin D9k 309
Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation 307
A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase Enzyme. 306
Structure-function relationships of the alpha(1b)-adrenergic receptor 304
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: A docking-based approach 303
Computational simulations of stem-cell factor c-Kit receptor interaction 300
Adenosine A(2A)-dopamine D-2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders 298
A Quantum Chemical QSAR Study of Carbonic Anhydrase Inhibition by Sulfonamides. 289
Theoretical investigation of IL-6 multiprotein receptor assembly 288
Development of an IL-6 antagonist peptide that induces apoptosis in IL-6 dependent 7TD1 cells. 286
Development of Quantitative Structure-Property Relationships (QSPR) using calculated descriptors for the prediction of the physico-chemical properties (nD, r, bp, e and h) of a series of organic solvents. 281
Mutational and computational analysis of the alpha-1b adrenergic receptor.Involvement of basic and hydrophobic residues in receptor activation and G protein coupling 278
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling 278
Prototropic molecular forms and theoretical descriptors in QSAR analysis 277
Three dimensional molecular modeling of the α1a-adrenoceptor. Direct 3D-QSAR modeling of selective antagonists 277
Theoretical quantitative structure-activity analysis of quinuclidine-based muscarinic cholinergic receptor ligands 276
The 2-Methoxyethanol + 1,2-Dimethoxyethane + Water Ternary System: Static Relative Permittivity from -10 to 80 °C 276
Theoretical study on the electrostatically driven step of receptor-G protein recognition 273
The ad hoc supermolecule approach to receptor ligand design 272
A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibition by Heterocyclic Sulfonamides. 271
Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic Anhydrase. 271
Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome F 271
Update 1 of: Computational Modeling Approaches to Structure-Function Analysis of G Protein-Coupled Receptors 265
Experimental and Theoretical Study of Electronic Substituent Effects in 4-Aminoaryl (4-Substituted Aryl) Sulphones. 264
Theoretical quantitative structure-activity analysis and pharmacophore modelling of selective non congeneric α1a-adrenergic antagonists 261
Use of the supermolecule approach to derive molecular similarity descriptors for QSAR analysis. 260
Molecular dynamics of guest radicals in urea inclusion compounds 258
Theoretical study on receptor-G protein recognition: new insights into the mechanism of the α1b-adrenergic receptor activation 258
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives 256
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists 256
Correlation and Multivariate Analyses of the Spectroscopic Data in 4'-Substituted 4-Nitro-difhenylsulfones 255
Comparative QSAR Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Design of Some New Derivatives with Improved Petency. 254
Adenosine A(2A)-dopamine D2 receptor-receptor heteromerization - Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer 252
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor 251
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists 249
Multiscale quantum chemical approaches to QSAR modeling and drug design 249
Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis 248
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 247
Ligand-Receptor Communication and Drug Design 245
Computer simulations of signal transduction mechanism in alpha 1B-adrenergic and m3-muscarinic receptors 244
A Theoretical Study of the Structure-Activity Relationship in Diarylsulphones. Comparison with Sulfa Drugs. 242
Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands 241
Theoretical investigation of substrate specificity for cytochromes p450 IA2, p450 IID6 and p450 IIIA4 241
Theoretical quantitative structure-activity relationship analysis of congeneric and non-congeneric α1-adrenoceptor antagonists: a chemometric study 238
Seeking for binding determinants of the prion protein to human plasminogen 236
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors 230
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 230
Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes 228
The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action 225
The heuristic-direct approach to quantitative structure-activity relationship analysis 224
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 224
Theoretical QSAR analysis on three dimensional models of the complexes between peptide and non-peptide antagonists with the ETA and ETB receptors 223
Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulphones. Comparison with Sulfanilamides. 222
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases 221
The heuristic-direct approach to theoretical quantitative structure activity relationship analysis of α1- adrenoceptor ligands 220
Design, Synthesis, Strucural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure 218
Conformational analysis and theoretical quantitative size and shape-affinity relationships of N-4-protonated N-1-arylpiperazine 5-HT1A serotoninergic ligands 216
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor 216
Molecular modeling and quantitaive structure activity relationship analysis using theoretical descriptors of 1,4-benzodioxan (WB-4101) related-compounds alpha-1-adrenergic antagonists 213
Constitutively active α1B-adrenergic receptor mutants: potential mechanisms underlying receptor activation 210
Computational modeling of selective pharmacophores at the alpha1-adrenergic receptors 209
Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling 207
The Interactions of 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands 204
THEORETICAL VERSUS EMPIRICAL MOLECULAR DESCRIPTORS IN MONOSUBSTITUTED BENZENES - A CHEMOMETRIC STUDY 203
ELECTRONIC AND ELECTROSTATIC ASPECTS OF CARBONIC-ANHYDRASE INHIBITION BY SULFONAMIDES 192
The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships 192
The Heuristic-Direct approach to Quantitative Structure-Activity Relationship Analysis of Ligand-G Protein Coupled Receptor Complexes 188
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation 184
QSAR Analysis Using Theoretical Molecular Descriptors in 2,4-Diamino-6,7-Dimethoxy Quinazoline 1-Adrenoceptor Antagonists. 184
Structure-Activity Relationship in Dihydropteroate Synthase Inhibition by Sulfanilamides. Comparison with the Antibacterial Activity. 181
Computer modeling of size and shape descriptors of alpha 1-adrenergic receptor antagonists and quantitative structure-affinity/selectivity relationships 179
Relevance of theoretical molecular descriptors in quantitative structure-activity relationship analysis of alpha 1-adrenergic receptor antagonists 179
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 177
Novel 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities 173
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists 170
Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors 167
Constitutively active receptor mutants as probes for studying the mechanisms underlying G protein-coupled receptor activation 167
The Heuristic-Direct Approach to QSAR Analysis of Ligand-G-Protein Coupled Receptor Complexes 166
Protonation States and Conformational Dynamics in Ligand-Target Recognition and Binding 156
Theoretical descriptors in quantitative structure - Affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(Alpha) receptor antagonists 155
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity 152
Theoretical conformational analysis, electronic structure and molecular modelling studies in dihydropteroate synthase in hibition by multisubstituted s 147
Direct and Indirect Theoretical QSAR Modelling in Sulfonamide Carbonic Anhydrase Inhibitors 145
Totale 25.494
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Categoria #
all - tutte 97.563
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 97.563
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021105 0 0 0 0 0 0 0 0 0 0 0 105
2021/20221.919 65 287 200 138 43 109 208 62 159 136 301 211
2022/20231.757 208 182 136 141 256 320 36 161 219 9 55 34
2023/2024922 29 60 92 63 255 83 45 115 20 32 35 93
2024/20254.588 283 57 56 255 783 592 333 296 406 214 681 632
2025/20267.901 603 380 810 1.079 1.206 694 789 383 823 605 358 171
Totale 26.009