Sfoglia per Autore
Topical 5-Fluorouracil Elicits Regressions of BRAF Inhibitor–Induced Cutaneous Squamous Cell Carcinoma
2013 Viros, Amaya; Hayward, Robert; Martin, Matthew; Yashar, Sharona; Yu, Clarissa C.; Sanchez Laorden, Berta; Zambon, Alfonso; Niculescu Duvaz, Dan; Springer, Caroline; Lo, Roger S; Marais, Richard
Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents
2013 Niculescu Duvaz, Dan; Niculescu Duvaz, Ion; Suijkerbuijk, Bart M. J. M.; Ménard, Delphine; Zambon, Alfonso; Davies, Lawrence; Pons, Jean Francois; Whittaker, Steven; Marais, Richard; Springer, Caroline J.
BRAF as a therapeutic target: A patent review (2006-2012)
2013 Zambon, Alfonso; Niculescu Duvaz, Dan; Niculescu Duvaz, Ion; Marais, Richard; Springer, Caroline J.
Preparation of 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for treating cancer
2013 Springer, Caroline Joy; Marais, Richard; Girotti, Romina; Niculescu-Duvaz, Dan; Niculescu-Duvaz, Ion; Zambon, Alfonso
BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling
2014 Sanchez Laorden, Berta; Viros, Amaya; Girotti, Maria Romina; Pedersen, Malin; Saturno, Grazia; Zambon, Alfonso; Niculescu Duvaz, Dan; Turajlic, Samra; Hayes, Andrew; Gore, Martin; Larkin, James; Lorigan, Paul; Cook, Martin; Springer, Caroline; Marais, Richard
Abstract 3704: Novel panRAF inhibitors active in melanomas that are resistant to BRAF-selective, or BRAF-selective/MEK inhibitor combinations
2014 Girotti, Maria R.; Lopes, Filipa; Preece, Natasha; Niculescu Duvaz, Dan; Zambon, Alfonso; Davies, Lawrence; Whittaker, Steven; Saturno, Grazia; Viros, Amaya; Pedersen, Malin; Suijkerbuijk, Bart MJM; Menard, Delphine; Mcleary, Robert; Johnson, Louise; Fish, Laura; Ejiama, Sarah; Sanchez Laorden, Berta; Carragher, Neil; Macleod, Kenneth; Ashton, Garry; Marusiak, Anna; Fusi, Alberto; Brognard, John; Frame, Margaret; Lorigan, Paul; Springer, Caroline J.; Marais, Richard
PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H PYRIDO2,3-B PYRAZIN-3-ONE DERIVATIVES
2014 Zambon, Alfonso; Niculescu-Duvaz, Dan; Chubb, Richard; Springer, Caroline Joy
1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-2-FLUORO-4-(3-OXO-4H-PYRIDO2,3-BPYRAZIN-8-YL)OXYPHENYLUREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
2014 Joy Springer, Caroline; Marais Romina Girotti, Richard; Niculescu-Duvaz, Dan; Niculescu-Duvaz, Ion; Zambon, Alfonso
Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma
2015 Girotti, Maria Romina; Lopes, Filipa; Preece, Natasha; Niculescu Duvaz, Dan; Zambon, Alfonso; Davies, Lawrence; Whittaker, Steven; Saturno, Grazia; Viros, Amaya; Pedersen, Malin; Suijkerbuijk, Bart M. J. M.; Menard, Delphine; Mcleary, Robert; Johnson, Louise; Fish, Laura; Ejiama, Sarah; Sanchez Laorden, Berta; Hohloch, Juliane; Carragher, Neil; Macleod, Kenneth; Ashton, Garry; Marusiak, Anna A.; Fusi, Alberto; Brognard, John; Frame, Margaret; Lorigan, Paul; Marais, Richard; Springer, Caroline
A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors
2016 Hooper, A.; Zambon, Alfonso; Springer, C. J.
Novel oligothiophenes with reduced HOMO-LUMO band gap for Optoelectonics
2017 Parenti, Francesca; Buffagni, Mirko; Zambon, Alfonso; Caselli, Monica; Vanossi, Davide; Mucci, Adele
Erratum: Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma (Cancer Cell (2015) 27(1) (85–96) (S1535610814004577) (10.1016/j.ccell.2014.11.006))
2017 Girotti, M. R.; Lopes, F.; Preece, N.; Niculescu-Duvaz, D.; Zambon, A.; Davies, L.; Whittaker, S.; Saturno, G.; Viros, A.; Pedersen, M.; Suijkerbuijk, B. M. J. M.; Menard, D.; Mcleary, R.; Johnson, L.; Fish, L.; Ejiama, S.; Sanchez-Laorden, B.; Hohloch, J.; Carragher, N.; Macleod, K.; Ashton, G.; Marusiak, A. A.; Fusi, A.; Brognard, J.; Frame, M.; Lorigan, P.; Marais, R.; Springer, C.
1 - ( 5 - TERT - BUTYL - 2 - ARYL - PYRAZOL - 3 - YL ) . 3 - 12 - FLUORO - 4 - [ ( 3 - OXO - 4H - PYRIDO [ 2 . 3 - BJPYRAZIN - 8 - YL ) OXY | PHENYLJUREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
2017 Joy SPRINGER, Caroline; Marais, Richard; Girotti, Romina; - DUVAZ, Dan NICULESCU; - DUVAZ, Ion NICULESCU; Zambon, Alfonso
LYSYL OXIDASE INHIBITORS
2017 Marais, Richard; Springer, Caroline; NICULESCU-DUVAZ, Dan; Miller, Natalie; Aljarah, Mohammed; Zambon, Alfonso; Leung, Leo; Smithen, Deborah; Brown, Michael; Tang, Haoran
Thiophene based A-D-A small molecules with a dithienosilole core: synthesis, theoretical calculations and optoelectronic properties
2018 Parenti, Francesca; Buffagni, Mirko; Caselli, Monica; Mucci, Adele; Pigani, Laura; Vanossi, Davide; Zambon, Alfonso
Non canonical Cyclic Nucleotides Monophosphates in Aphanizomenon flosaquae: nuclear magnetic resonance and mass spectrometry
2019 Righi, Valeria; Zambon, Alfonso; Parenti, Francesca; Rossi, Maria Cecilia; Libertini, Emanuela; Mucci, Adele
Non-canonical Cyclic Nucleoside Monophosphates in Aphanizomenon flos-aquae: nuclear magnetic resonance and mass spectrometry
2019 Righi, V.; Zambon, A.; Parenti, F.; Rossi, M. C.; Mucci, A.
NON CANONICAL CYCLIC NUCLEOTIDES MONOPHOSPHATES IN APHANIZOMENON FLOS-AQUAE: NUCLEAR MAGNETIC RESONANCE AND MASS SPECTROMETRY
2019 Righi, V.; Zambon, A.; Parenti, F.; Rossi, M. C.; Mucci, A.
Mesoporous bioactive glasses doped with cerium: Investigation over enzymatic-like mimetic activities and bioactivity
2019 Nicolini, V.; Malavasi, G.; Lusvardi, G.; Zambon, A.; Benedetti, F.; Cerrato, G.; Valeri, S.; Luches, P.
Structure Model and Toxicity of the Product of Biodissolution of Chrysotile Asbestos in the Lungs
2019 Gualtieri, A. F.; Lusvardi, G.; Pedone, A.; Di Giuseppe, D.; Zoboli, A.; Mucci, A.; Zambon, A.; Filaferro, M.; Vitale, G.; Benassi, M.; Avallone, R.; Pasquali, L.; Lassinantti Gualtieri, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Topical 5-Fluorouracil Elicits Regressions of BRAF Inhibitor–Induced Cutaneous Squamous Cell Carcinoma | 1-gen-2013 | Viros, Amaya; Hayward, Robert; Martin, Matthew; Yashar, Sharona; Yu, Clarissa C.; Sanchez Laorden, Berta; Zambon, Alfonso; Niculescu Duvaz, Dan; Springer, Caroline; Lo, Roger S; Marais, Richard | |
| Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents | 1-gen-2013 | Niculescu Duvaz, Dan; Niculescu Duvaz, Ion; Suijkerbuijk, Bart M. J. M.; Ménard, Delphine; Zambon, Alfonso; Davies, Lawrence; Pons, Jean Francois; Whittaker, Steven; Marais, Richard; Springer, Caroline J. | |
| BRAF as a therapeutic target: A patent review (2006-2012) | 1-gen-2013 | Zambon, Alfonso; Niculescu Duvaz, Dan; Niculescu Duvaz, Ion; Marais, Richard; Springer, Caroline J. | |
| Preparation of 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for treating cancer | 13-nov-2013 | Springer, Caroline Joy; Marais, Richard; Girotti, Romina; Niculescu-Duvaz, Dan; Niculescu-Duvaz, Ion; Zambon, Alfonso | |
| BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling | 1-gen-2014 | Sanchez Laorden, Berta; Viros, Amaya; Girotti, Maria Romina; Pedersen, Malin; Saturno, Grazia; Zambon, Alfonso; Niculescu Duvaz, Dan; Turajlic, Samra; Hayes, Andrew; Gore, Martin; Larkin, James; Lorigan, Paul; Cook, Martin; Springer, Caroline; Marais, Richard | |
| Abstract 3704: Novel panRAF inhibitors active in melanomas that are resistant to BRAF-selective, or BRAF-selective/MEK inhibitor combinations | 1-gen-2014 | Girotti, Maria R.; Lopes, Filipa; Preece, Natasha; Niculescu Duvaz, Dan; Zambon, Alfonso; Davies, Lawrence; Whittaker, Steven; Saturno, Grazia; Viros, Amaya; Pedersen, Malin; Suijkerbuijk, Bart MJM; Menard, Delphine; Mcleary, Robert; Johnson, Louise; Fish, Laura; Ejiama, Sarah; Sanchez Laorden, Berta; Carragher, Neil; Macleod, Kenneth; Ashton, Garry; Marusiak, Anna; Fusi, Alberto; Brognard, John; Frame, Margaret; Lorigan, Paul; Springer, Caroline J.; Marais, Richard | |
| PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H PYRIDO2,3-B PYRAZIN-3-ONE DERIVATIVES | 25-nov-2014 | Zambon, Alfonso; Niculescu-Duvaz, Dan; Chubb, Richard; Springer, Caroline Joy | |
| 1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-2-FLUORO-4-(3-OXO-4H-PYRIDO2,3-BPYRAZIN-8-YL)OXYPHENYLUREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER | 25-nov-2014 | Joy Springer, Caroline; Marais Romina Girotti, Richard; Niculescu-Duvaz, Dan; Niculescu-Duvaz, Ion; Zambon, Alfonso | |
| Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma | 1-gen-2015 | Girotti, Maria Romina; Lopes, Filipa; Preece, Natasha; Niculescu Duvaz, Dan; Zambon, Alfonso; Davies, Lawrence; Whittaker, Steven; Saturno, Grazia; Viros, Amaya; Pedersen, Malin; Suijkerbuijk, Bart M. J. M.; Menard, Delphine; Mcleary, Robert; Johnson, Louise; Fish, Laura; Ejiama, Sarah; Sanchez Laorden, Berta; Hohloch, Juliane; Carragher, Neil; Macleod, Kenneth; Ashton, Garry; Marusiak, Anna A.; Fusi, Alberto; Brognard, John; Frame, Margaret; Lorigan, Paul; Marais, Richard; Springer, Caroline | |
| A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors | 1-gen-2016 | Hooper, A.; Zambon, Alfonso; Springer, C. J. | |
| Novel oligothiophenes with reduced HOMO-LUMO band gap for Optoelectonics | 1-gen-2017 | Parenti, Francesca; Buffagni, Mirko; Zambon, Alfonso; Caselli, Monica; Vanossi, Davide; Mucci, Adele | |
| Erratum: Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma (Cancer Cell (2015) 27(1) (85–96) (S1535610814004577) (10.1016/j.ccell.2014.11.006)) | 1-gen-2017 | Girotti, M. R.; Lopes, F.; Preece, N.; Niculescu-Duvaz, D.; Zambon, A.; Davies, L.; Whittaker, S.; Saturno, G.; Viros, A.; Pedersen, M.; Suijkerbuijk, B. M. J. M.; Menard, D.; Mcleary, R.; Johnson, L.; Fish, L.; Ejiama, S.; Sanchez-Laorden, B.; Hohloch, J.; Carragher, N.; Macleod, K.; Ashton, G.; Marusiak, A. A.; Fusi, A.; Brognard, J.; Frame, M.; Lorigan, P.; Marais, R.; Springer, C. | |
| 1 - ( 5 - TERT - BUTYL - 2 - ARYL - PYRAZOL - 3 - YL ) . 3 - 12 - FLUORO - 4 - [ ( 3 - OXO - 4H - PYRIDO [ 2 . 3 - BJPYRAZIN - 8 - YL ) OXY | PHENYLJUREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER | 29-giu-2017 | Joy SPRINGER, Caroline; Marais, Richard; Girotti, Romina; - DUVAZ, Dan NICULESCU; - DUVAZ, Ion NICULESCU; Zambon, Alfonso | |
| LYSYL OXIDASE INHIBITORS | 13-ott-2017 | Marais, Richard; Springer, Caroline; NICULESCU-DUVAZ, Dan; Miller, Natalie; Aljarah, Mohammed; Zambon, Alfonso; Leung, Leo; Smithen, Deborah; Brown, Michael; Tang, Haoran | |
| Thiophene based A-D-A small molecules with a dithienosilole core: synthesis, theoretical calculations and optoelectronic properties | 1-gen-2018 | Parenti, Francesca; Buffagni, Mirko; Caselli, Monica; Mucci, Adele; Pigani, Laura; Vanossi, Davide; Zambon, Alfonso | |
| Non canonical Cyclic Nucleotides Monophosphates in Aphanizomenon flosaquae: nuclear magnetic resonance and mass spectrometry | 1-gen-2019 | Righi, Valeria; Zambon, Alfonso; Parenti, Francesca; Rossi, Maria Cecilia; Libertini, Emanuela; Mucci, Adele | |
| Non-canonical Cyclic Nucleoside Monophosphates in Aphanizomenon flos-aquae: nuclear magnetic resonance and mass spectrometry | 1-gen-2019 | Righi, V.; Zambon, A.; Parenti, F.; Rossi, M. C.; Mucci, A. | |
| NON CANONICAL CYCLIC NUCLEOTIDES MONOPHOSPHATES IN APHANIZOMENON FLOS-AQUAE: NUCLEAR MAGNETIC RESONANCE AND MASS SPECTROMETRY | 1-gen-2019 | Righi, V.; Zambon, A.; Parenti, F.; Rossi, M. C.; Mucci, A. | |
| Mesoporous bioactive glasses doped with cerium: Investigation over enzymatic-like mimetic activities and bioactivity | 1-gen-2019 | Nicolini, V.; Malavasi, G.; Lusvardi, G.; Zambon, A.; Benedetti, F.; Cerrato, G.; Valeri, S.; Luches, P. | |
| Structure Model and Toxicity of the Product of Biodissolution of Chrysotile Asbestos in the Lungs | 1-gen-2019 | Gualtieri, A. F.; Lusvardi, G.; Pedone, A.; Di Giuseppe, D.; Zoboli, A.; Mucci, A.; Zambon, A.; Filaferro, M.; Vitale, G.; Benassi, M.; Avallone, R.; Pasquali, L.; Lassinantti Gualtieri, M. |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile