TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
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Continente #
NA - Nord America 4.100
AS - Asia 3.980
EU - Europa 3.110
SA - Sud America 438
AF - Africa 93
Continente sconosciuto - Info sul continente non disponibili 73
OC - Oceania 13
Totale 11.807
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Nazione #
US - Stati Uniti d'America 3.952
IT - Italia 1.317
CN - Cina 1.265
SG - Singapore 1.157
DE - Germania 431
VN - Vietnam 387
HK - Hong Kong 358
BR - Brasile 327
SE - Svezia 276
GB - Regno Unito 235
KR - Corea 215
RU - Federazione Russa 155
FR - Francia 139
FI - Finlandia 113
BD - Bangladesh 106
ID - Indonesia 98
IN - India 90
CA - Canada 82
ES - Italia 66
NL - Olanda 62
JP - Giappone 54
IQ - Iraq 43
CH - Svizzera 42
LT - Lituania 39
PL - Polonia 37
IE - Irlanda 36
AR - Argentina 34
BE - Belgio 28
MX - Messico 28
ZA - Sudafrica 28
PK - Pakistan 22
TR - Turchia 22
AT - Austria 20
UA - Ucraina 19
MY - Malesia 18
CL - Cile 17
UZ - Uzbekistan 17
EC - Ecuador 16
IR - Iran 15
SA - Arabia Saudita 15
MA - Marocco 13
TW - Taiwan 13
CZ - Repubblica Ceca 12
GR - Grecia 12
PH - Filippine 12
PY - Paraguay 12
VE - Venezuela 12
AE - Emirati Arabi Uniti 11
BG - Bulgaria 11
KE - Kenya 11
TN - Tunisia 11
CO - Colombia 10
AU - Australia 9
JM - Giamaica 9
CR - Costa Rica 8
TH - Thailandia 8
ET - Etiopia 7
NP - Nepal 7
DK - Danimarca 6
JO - Giordania 6
LI - Liechtenstein 6
NO - Norvegia 6
RO - Romania 6
RS - Serbia 6
BY - Bielorussia 5
DZ - Algeria 5
EG - Egitto 5
GT - Guatemala 5
HN - Honduras 5
KZ - Kazakistan 5
MO - Macao, regione amministrativa speciale della Cina 5
UY - Uruguay 5
AL - Albania 4
AZ - Azerbaigian 4
IL - Israele 4
LV - Lettonia 4
NZ - Nuova Zelanda 4
PE - Perù 4
PT - Portogallo 4
BH - Bahrain 3
EE - Estonia 3
GE - Georgia 3
HU - Ungheria 3
LB - Libano 3
LK - Sri Lanka 3
MD - Moldavia 3
NI - Nicaragua 3
PR - Porto Rico 3
SN - Senegal 3
SV - El Salvador 3
DO - Repubblica Dominicana 2
GH - Ghana 2
KG - Kirghizistan 2
LU - Lussemburgo 2
NG - Nigeria 2
PS - Palestinian Territory 2
SC - Seychelles 2
AF - Afghanistan, Repubblica islamica di 1
AO - Angola 1
BN - Brunei Darussalam 1
Totale 11.723
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Città #
Singapore 716
Santa Clara 678
Hefei 613
San Jose 523
Ashburn 433
Hong Kong 344
Council Bluffs 278
Modena 197
Seoul 196
Frankfurt am Main 167
Ho Chi Minh City 141
London 136
Chandler 135
New York 131
Los Angeles 121
Bologna 119
Nyköping 113
Beijing 111
Jakarta 81
Hanoi 80
The Dalles 76
Helsinki 75
Milan 74
Parma 62
Munich 61
Reggio Emilia 60
Boardman 57
Dallas 48
Moscow 47
Chicago 45
Shanghai 45
Lauterbourg 43
Buffalo 41
Orem 37
Fairfield 36
São Paulo 36
Kent 33
Dublin 30
Warsaw 30
Houston 28
Rome 27
Seattle 25
Tokyo 25
Amsterdam 24
Denver 24
Formigine 24
Lappeenranta 23
Phoenix 22
Madrid 21
Toronto 21
Zurich 21
Atlanta 20
Turin 20
Padova 19
Da Nang 18
Nuremberg 18
Princeton 18
San Diego 18
Wilmington 18
Piacenza 17
Stockholm 17
Chennai 16
Leuven 15
Paris 15
Salt Lake City 15
Boston 14
Decatur 14
Sassuolo 14
Tashkent 14
Barcelona 13
Ferrara 13
Johannesburg 13
Manchester 13
Cambridge 12
Düsseldorf 12
Hangzhou 12
Osnabrück 12
Perugia 12
Portsmouth 12
Ravenna 12
Vienna 12
Washington 12
Baghdad 11
Brooklyn 11
Guangzhou 11
Mexico City 11
Naples 11
Ottawa 11
Poplar 11
Rio de Janeiro 11
Santiago 11
Brussels 10
Charlotte 10
Haiphong 10
Hamburg 10
Nairobi 10
Padua 10
Redondo Beach 10
Tehran 10
Turku 10
Totale 7.183
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Nome #
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 321
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 317
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 305
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 284
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 251
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 251
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 248
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 246
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 245
Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases 245
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 240
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates. 237
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 237
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 233
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 232
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 229
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 223
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 220
Current Treatments to Control African Trypanosomiasis and One Health Perspective 220
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 219
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 216
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 214
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 213
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 206
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 204
Precision medicine through proteomics studies in drug resistant colorectal cancer 200
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 197
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 197
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 196
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 195
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 194
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 192
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 192
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 191
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 189
Drug discovery of pyrazolo-piperidinone inhibitors targeting YAP:TEAD interaction and development of a fluorescence anisotropy assay for high-throughput screening 189
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 187
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 185
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 184
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective 183
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 179
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 178
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 177
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 175
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 174
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 172
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 171
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease. 168
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 162
integrazione della proteomica mediante spettrometria di massa nel processo di Drug Discovery come strumento innovativo per superare la farmacoresistenza 161
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 152
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 141
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance. 139
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 137
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 133
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis. 126
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 115
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 106
IDENTIFICATION OF PYRAZOLO-PIPERIDINONE DERIVATIVES TARGETING YAP-TEAD INTERFACE 3 AS ANTICANCER AGENTS THROUGH INTEGRATED VIRTUAL SCREENING AND MASS SPECTROMETRY PROTEOMICS 101
A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion 13
Totale 11.807
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Categoria #
all - tutte 46.685
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.685
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022329 0 0 0 2 2 47 18 32 50 41 85 52
2022/2023859 87 69 30 61 76 71 85 99 122 32 73 54
2023/20241.302 62 78 87 73 321 86 84 104 37 40 181 149
2024/20253.270 112 46 129 199 556 465 211 245 329 143 409 426
2025/20265.116 473 319 445 613 638 285 674 247 447 500 311 164
2026/2027837 115 233 355 134 0 0 0 0 0 0 0 0
Totale 11.807