TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 1.615
NA - Nord America 1.060
AS - Asia 646
AF - Africa 10
SA - Sud America 8
OC - Oceania 4
Totale 3.343
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.038
IT - Italia 820
DE - Germania 245
SG - Singapore 226
SE - Svezia 185
CN - Cina 170
HK - Hong Kong 93
FI - Finlandia 58
GB - Regno Unito 49
FR - Francia 39
ID - Indonesia 36
ES - Italia 33
LT - Lituania 31
IE - Irlanda 30
CH - Svizzera 27
BE - Belgio 26
JP - Giappone 26
IN - India 23
CA - Canada 22
NL - Olanda 16
KR - Corea 12
TW - Taiwan 12
IR - Iran 10
CZ - Repubblica Ceca 9
MY - Malesia 9
BG - Bulgaria 7
TR - Turchia 7
LI - Liechtenstein 6
CL - Cile 5
DK - Danimarca 5
GR - Grecia 5
PH - Filippine 5
UA - Ucraina 5
ZA - Sudafrica 5
PK - Pakistan 4
PL - Polonia 4
VN - Vietnam 4
AU - Australia 3
MD - Moldavia 3
NO - Norvegia 3
RO - Romania 3
RS - Serbia 3
TN - Tunisia 3
BR - Brasile 2
IQ - Iraq 2
MO - Macao, regione amministrativa speciale della Cina 2
PT - Portogallo 2
TH - Thailandia 2
AT - Austria 1
BD - Bangladesh 1
CO - Colombia 1
EG - Egitto 1
GH - Ghana 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
NZ - Nuova Zelanda 1
Totale 3.343
Salva come PNG Salva come JPEG
Città #
Santa Clara 264
Singapore 184
Modena 153
Frankfurt am Main 152
Chandler 134
Nyköping 113
Hong Kong 84
Bologna 68
New York 67
Ashburn 62
Helsinki 47
Boardman 41
Fairfield 36
Jakarta 36
Milan 35
Parma 33
Reggio Emilia 29
Shanghai 29
Dublin 24
Munich 23
Houston 19
Padova 19
Seattle 19
Formigine 18
Princeton 18
San Diego 17
Turin 17
Beijing 16
Leuven 15
Piacenza 15
Sassuolo 14
Decatur 13
Wilmington 13
Zurich 13
Hangzhou 12
London 12
Osnabrück 12
Perugia 12
Lappeenranta 11
Ottawa 11
Barcelona 10
Cambridge 10
Rome 10
Tehran 10
Woodbridge 10
Brussels 9
Madrid 9
San Giovanni Suergiu 9
Amsterdam 8
Brno 8
Paris 8
Washington 8
Ann Arbor 7
Argenta 7
Bomporto 7
Sofia 7
Vicenza 7
East Wenatchee 6
Rossdorf 6
Taichung 6
Verona 6
Bremen 5
Brescello 5
Cebu City 5
Dallas 5
Laval 5
Marktbreit 5
Marseille 5
Rimini 5
Valby 5
Albino 4
Assago 4
Berlin 4
Boston 4
Castelfranco Emilia 4
Chennai 4
Finale Emilia 4
Ho Chi Minh City 4
Hyderabad 4
Ispra 4
Lausanne 4
Messina 4
Montecarlo 4
Naples 4
Reims 4
Riverside 4
Saint-Fons 4
Santiago 4
Santiago de Compostela 4
Tokyo 4
UEmraniye 4
Vauderens 4
Villeneuve-d'Ascq 4
Arceto 3
Aversa 3
Bassano del Grappa 3
Brescia 3
Capannori 3
Carpi 3
Cellatica 3
Totale 2.236
Salva come PNG Salva come JPEG
Nome #
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 162
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 161
Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases 118
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 106
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 100
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 99
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 99
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 95
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 94
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 93
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 93
Current Treatments to Control African Trypanosomiasis and One Health Perspective 91
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 87
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 86
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 83
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 81
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 80
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates. 79
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 76
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 75
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 72
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 68
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 66
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 65
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis. 65
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 64
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 63
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 62
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 59
Precision medicine through proteomics studies in drug resistant colorectal cancer 58
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 55
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 53
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 53
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 52
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 50
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 49
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 46
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 45
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 44
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective 39
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 38
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 38
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 37
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 36
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 31
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 24
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 22
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance. 21
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease. 17
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 17
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 16
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 14
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 4
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 3
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 2
Totale 3.406
Salva come PNG Salva come JPEG
Categoria #
all - tutte 19.507
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.507
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202154 0 0 0 0 0 0 0 0 3 10 11 30
2021/2022369 26 12 2 2 2 47 18 32 50 41 85 52
2022/2023859 87 69 30 61 76 71 85 99 122 32 73 54
2023/20241.302 62 78 87 73 321 86 84 104 37 40 181 149
2024/2025822 112 46 129 199 336 0 0 0 0 0 0 0
Totale 3.406