CASELLI, Emilia
CASELLI, Emilia
Dipartimento di Scienze della Vita
1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase
2020-01-01 Caselli, E.; Fini, F.; Introvigne, M. L.; Stucchi, M.; Taracila, M. A.; Fish, E. R.; Smolen, K. A.; Rather, P. N.; Powers, R. A.; Wallar, B. J.; Bonomo, R. A.; Prati, F.
Acetamidomethaneboronic acids bearing the R1 side chains of beta-lactams as inhibitors of beta-lactamase enzymes
L. C., Blaszczak; Caselli, Emilia; Prati, Fabio; B. K., Shoichet
Acido alfa-Acetammido-alfa-Fenilmetanboronico come Agente Derivatizzante Chirale per la Determinazione dell’Eccesso Enantiomerico di 1,2-Dioli
2003-01-01 B., Bonfiglio; Caselli, Emilia; Forni, Arrigo; Danieli, Chiara; Prati, Fabio
Biocatalytic asymmetric synthesis of (S)- and (R)-Timolol
2004-01-01 Tosi, Giovanni; F., Zironi; Caselli, Emilia; Forni, Arrigo; Prati, Fabio
Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii
2014-01-01 R. A., Powers; H. C., Swanson; M. A., Taracila; N. W., Florek; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; R. A., Bonomo; B. J., Wallar
Boronic acid inhibitors of beta-lactamases as therapeutic agents in treatment of antibiotic-resistant infection diseases
Prati, Fabio; Caselli, Emilia
Boronic acid transition state inhibitors active against KPC and other class a β-lactamases: Structure-activity relationships as a guide to inhibitor design
2016-01-01 Rojas, Laura J.; Taracila, Magdalena A.; Papp Wallace, Krisztina M.; Bethel, Christopher R.; Caselli, Emilia; Romagnoli, Chiara; Winkler, Marisa L.; Spellberg, Brad; Prati, Fabio; Bonomo, Robert A.
Chemo-enzymatic synthesis of levodropropizine
2003-01-01 Caselli, Emilia; Tosi, Giovanni; Forni, Arrigo; Bucciarelli, Maria; Prati, Fabio
Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors
2015-01-01 Caselli, Emilia; Romagnoli, Chiara; Vahabi, Roza; Taracila, Magdalena A; Bonomo, Robert A; Prati, Fabio
A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening
2002-01-01 Susan L., Mcgovern; Caselli, Emilia; Nikolaus, Grigorieff; Brian K., Shoichet
A comprehensive and contemporary “snapshot” of β-lactamases in carbapenem resistant Acinetobacter baumannii
2021-01-01 Hujer, A. M.; Hujer, K. M.; Leonard, D. A.; Powers, R. A.; Wallar, B. J.; Mack, A. R.; Taracila, M. A.; Rather, P. N.; Higgins, P. G.; Prati, F.; Caselli, E.; Marshall, S. H.; Clarke, T.; Greco, C.; Venepally, P.; Brinkac, L.; Kreiswirth, B. N.; Fouts, D. E.; Bonomo, R. A.
Crystal structures of KPC-2 and SHV-1 β-lactamases in complex with the boronic acid transition state analog S02030
2016-01-01 Nguyen, Nhu Q.; Krishnan, Nikhil P.; Rojas, Laura J.; Prati, Fabio; Caselli, Emilia; Romagnoli, Chiara; Bonomo, Robert A.; Van Den Akker, Focco
Deciphering the evolution of cephalosporin resistance to ceftolozane-tazobactam in pseudomonas aeruginosa
2018-01-01 Barnes, Melissa D.; Taracila, Magdalena A.; Rutter, Joseph D.; Bethel, Christopher R.; Galdadas, Ioannis; Hujer, Andrea M.; Caselli, Emilia; Prati, Fabio; Dekker, John P.; Papp-Wallace, Krisztina M.; Haider, Shozeb; Bonomo, Robert A.
Design and exploration of novel boronic acid Inhibitors reveals important Interactions with a clavulanic acid-resistant sulfhydryl- variable (SHV) β‑ lactamase
2013-01-01 Marisa L., Winkler; Elizabeth A., Rodkey; Magdalena A., Taracila; Sarah M., Drawz; Christopher R., Bethel; Krisztina M., Papp Wallace; Kerri M., Smith; Yan, Xu; Jeffrey R., Dwulit Smith; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; Focco van den, Akker; Robert A., Bonomo
Design, synthesis, crystal structures and antimicrobial activity of sulfonamide boronic acids as beta-lactamase inhibitors
2010-01-01 Oliv, Eidam; Romagnoli, Chiara; Caselli, Emilia; Joel, Karpiak; Kerim, Babaoglu; Denise Teotico, Pohlhaus; Richard, Bonnet; Brian K., Shoichet; Prati, Fabio
Enantiomeric excess of 1,2-diols by formation of cyclic boronates: an improved method
2005-01-01 Morandi, Stefania; Caselli, Emilia; Forni, Arrigo; Bucciarelli, Maria; Torre, Giovanni; Prati, Fabio
Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases
2001-01-01 Caselli, Emilia; Powers, Ra; Blasczcak, Lc; Wu, Cye; Prati, Fabio; Shoichet, Bk
Exploring novel inhibitors of FOX-4 Class C β-lactamase
2010-01-01 S., Mallo; C., Bethel; F., Perez llarena; Prati, Fabio; Caselli, Emilia; M., Page; G., Bou; R., Bonomo
Exploring sequence requirements for C3/C4 carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase
2011-01-01 Sarah M., Drawz; Magdalena, Taracila; Caselli, Emilia; Prati, Fabio; Robert A., Bonomo
Fragment-guided Design of Subnanomolar β-Lactamase Inhibitors Active in vivo
2012-01-01 O., Eidam; Romagnoli, Chiara; G., Dalmasso; S., Barelier; Caselli, Emilia; R., Bonnet; B. K., Shoichet; Prati, Fabio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase | 1-gen-2020 | Caselli, E.; Fini, F.; Introvigne, M. L.; Stucchi, M.; Taracila, M. A.; Fish, E. R.; Smolen, K. A.; Rather, P. N.; Powers, R. A.; Wallar, B. J.; Bonomo, R. A.; Prati, F. | |
| Acetamidomethaneboronic acids bearing the R1 side chains of beta-lactams as inhibitors of beta-lactamase enzymes | - | L. C., Blaszczak; Caselli, Emilia; Prati, Fabio; B. K., Shoichet | |
| Acido alfa-Acetammido-alfa-Fenilmetanboronico come Agente Derivatizzante Chirale per la Determinazione dell’Eccesso Enantiomerico di 1,2-Dioli | 1-gen-2003 | B., Bonfiglio; Caselli, Emilia; Forni, Arrigo; Danieli, Chiara; Prati, Fabio | |
| Biocatalytic asymmetric synthesis of (S)- and (R)-Timolol | 1-gen-2004 | Tosi, Giovanni; F., Zironi; Caselli, Emilia; Forni, Arrigo; Prati, Fabio | |
| Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii | 1-gen-2014 | R. A., Powers; H. C., Swanson; M. A., Taracila; N. W., Florek; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; R. A., Bonomo; B. J., Wallar | |
| Boronic acid inhibitors of beta-lactamases as therapeutic agents in treatment of antibiotic-resistant infection diseases | - | Prati, Fabio; Caselli, Emilia | |
| Boronic acid transition state inhibitors active against KPC and other class a β-lactamases: Structure-activity relationships as a guide to inhibitor design | 1-gen-2016 | Rojas, Laura J.; Taracila, Magdalena A.; Papp Wallace, Krisztina M.; Bethel, Christopher R.; Caselli, Emilia; Romagnoli, Chiara; Winkler, Marisa L.; Spellberg, Brad; Prati, Fabio; Bonomo, Robert A. | |
| Chemo-enzymatic synthesis of levodropropizine | 1-gen-2003 | Caselli, Emilia; Tosi, Giovanni; Forni, Arrigo; Bucciarelli, Maria; Prati, Fabio | |
| Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors | 1-gen-2015 | Caselli, Emilia; Romagnoli, Chiara; Vahabi, Roza; Taracila, Magdalena A; Bonomo, Robert A; Prati, Fabio | |
| A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening | 1-gen-2002 | Susan L., Mcgovern; Caselli, Emilia; Nikolaus, Grigorieff; Brian K., Shoichet | |
| A comprehensive and contemporary “snapshot” of β-lactamases in carbapenem resistant Acinetobacter baumannii | 1-gen-2021 | Hujer, A. M.; Hujer, K. M.; Leonard, D. A.; Powers, R. A.; Wallar, B. J.; Mack, A. R.; Taracila, M. A.; Rather, P. N.; Higgins, P. G.; Prati, F.; Caselli, E.; Marshall, S. H.; Clarke, T.; Greco, C.; Venepally, P.; Brinkac, L.; Kreiswirth, B. N.; Fouts, D. E.; Bonomo, R. A. | |
| Crystal structures of KPC-2 and SHV-1 β-lactamases in complex with the boronic acid transition state analog S02030 | 1-gen-2016 | Nguyen, Nhu Q.; Krishnan, Nikhil P.; Rojas, Laura J.; Prati, Fabio; Caselli, Emilia; Romagnoli, Chiara; Bonomo, Robert A.; Van Den Akker, Focco | |
| Deciphering the evolution of cephalosporin resistance to ceftolozane-tazobactam in pseudomonas aeruginosa | 1-gen-2018 | Barnes, Melissa D.; Taracila, Magdalena A.; Rutter, Joseph D.; Bethel, Christopher R.; Galdadas, Ioannis; Hujer, Andrea M.; Caselli, Emilia; Prati, Fabio; Dekker, John P.; Papp-Wallace, Krisztina M.; Haider, Shozeb; Bonomo, Robert A. | |
| Design and exploration of novel boronic acid Inhibitors reveals important Interactions with a clavulanic acid-resistant sulfhydryl- variable (SHV) β‑ lactamase | 1-gen-2013 | Marisa L., Winkler; Elizabeth A., Rodkey; Magdalena A., Taracila; Sarah M., Drawz; Christopher R., Bethel; Krisztina M., Papp Wallace; Kerri M., Smith; Yan, Xu; Jeffrey R., Dwulit Smith; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; Focco van den, Akker; Robert A., Bonomo | |
| Design, synthesis, crystal structures and antimicrobial activity of sulfonamide boronic acids as beta-lactamase inhibitors | 1-gen-2010 | Oliv, Eidam; Romagnoli, Chiara; Caselli, Emilia; Joel, Karpiak; Kerim, Babaoglu; Denise Teotico, Pohlhaus; Richard, Bonnet; Brian K., Shoichet; Prati, Fabio | |
| Enantiomeric excess of 1,2-diols by formation of cyclic boronates: an improved method | 1-gen-2005 | Morandi, Stefania; Caselli, Emilia; Forni, Arrigo; Bucciarelli, Maria; Torre, Giovanni; Prati, Fabio | |
| Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases | 1-gen-2001 | Caselli, Emilia; Powers, Ra; Blasczcak, Lc; Wu, Cye; Prati, Fabio; Shoichet, Bk | |
| Exploring novel inhibitors of FOX-4 Class C β-lactamase | 1-gen-2010 | S., Mallo; C., Bethel; F., Perez llarena; Prati, Fabio; Caselli, Emilia; M., Page; G., Bou; R., Bonomo | |
| Exploring sequence requirements for C3/C4 carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase | 1-gen-2011 | Sarah M., Drawz; Magdalena, Taracila; Caselli, Emilia; Prati, Fabio; Robert A., Bonomo | |
| Fragment-guided Design of Subnanomolar β-Lactamase Inhibitors Active in vivo | 1-gen-2012 | O., Eidam; Romagnoli, Chiara; G., Dalmasso; S., Barelier; Caselli, Emilia; R., Bonnet; B. K., Shoichet; Prati, Fabio |