D'ARCA, Domenico
D'ARCA, Domenico
Dipartimento di Scienze Biomediche, Metaboliche e Neuroscienze
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells
2020-01-01 Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Francesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana Grazia; Costi, Maria Paola; D'Arca, Domenico
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties
2022-01-01 Tagliazucchi, Lorenzo; Venturelli, Alberto; Malpezzi, Giulia; Moschella, MARIA GAETANA; Aiello, Daniele; Lopresti, Ludovica; Pozzi, Cecilia; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Anticancer activity of green tea polyphenols in prostate gland
2012-01-01 Davalli, Pierpaola; F., Rizzi; A., Caporali; D., Pellacani; S., Davoli; S., Bettuzzi; M., Brausi; D'Arca, Domenico
ANTICANCER DRUGS
2015-01-01 Costantino, Luca; Costi, Maria Paola; Ponterini, Glauco; Marverti, Gaetano; Franchini, Silvia; Tondi, Donatella; D'Arca, Domenico; Ferrari, Stefania; Luciani, Rosaria; Venturelli, Alberto; Sammak, Susan; Lauriola, Angela; Gozzi, Gaia
Ca2+ depletion induces nuclear clusterin, a novel effector of apoptosis in immortalized human prostate cells
2005-01-01 Ae, Caccamo; Scaltriti, Maurizio; A., Caporali; D'Arca, Domenico; Corti, Arnaldo; D., Corvetta; A., Sala; S., Bettuzzi
Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin
2004-01-01 Ae, Caccamo; Scaltriti, Maurizio; A., Caporali; D'Arca, Domenico; F., Scorcioni; Astancolle, Serenella; M., Mangiola; S., Bettuzzi
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme
2021-01-01 Tagliazucchi, Lorenzo; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer
2004-01-01 Scaltriti, Maurizio; M., Brausi; A., Amorosi; A., Caporali; D'Arca, Domenico; Astancolle, Serenella; Corti, Arnaldo; S., Bettuzzi
Clusterin decreases oxidative stress in lung fibroblasts exposed to cigarette smoke
2006-01-01 Carnevali, S; Luppi, Fabrizio; D'Arca, Domenico; Caporali, A; Ruggieri, Mp; Vettori, Mv; Caglieri, A; Astancolle, Serenella; Panico, Francesca; Davalli, Pierpaola; Mutti, A; Fabbri, Leonardo; Corti, Arnaldo
Clusterin gene expression is down-regulated in transformed epithelial cells but up-regulated in fibroblasts from prostate cancer
2003-01-01 Bettuzzi, S; Scaltriti, M; Caporali, A; Brausi, M; Astancolle, S; D'Arca, D; Corti, A.
Clusterin is down-regulated during the progression of prostate cancer in the tramp mouse model but up-regulated during chemioprevention by green tea catechins administration
2003-01-01 Davalli, Pierpaola; Astancolle, Serenella; Caporali, A.; D'Arca, Domenico; Corti, Arnaldo; Brasi, M. B.
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth
2018-01-01 Saxena, Puneet; Severi, Leda; Santucci, Matteo; Taddia, Laura; Ferrari, Stefania; Luciani, Rosaria; Marverti, Gaetano; Marraccini, Chiara; Tondi, Donatella; Mor, Marco; Laura, Scalvini; Vitiello, Simone; Losi, Lorena; Fonda, Sergio; Pacifico, Salvatore; Guerrini, Remo; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones?
2017-01-01 Sacchetti, Francesca; D'Arca, Domenico; Genovese, Filippo; Pacifico, Salvatore; Maretti, Eleonora; Hanuskova, Miriam; Iannuccelli, Valentina; Costi, Maria Paola; Leo, Eliana Grazia
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth
2019-01-01 Pacifico, Salvatore; Santucci, Matteo; Luciani, Rosaria; Saxena, Puneet; Linciano, Pasquale; Ponterini, Glauco; Lauriola, Angela; D'Arca, Domenico; Marverti, Gaetano; Guerrini, Remo; Costi, Maria Paola
Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells
2020-01-01 Lauriola, Angela; Martello, Andrea; Fantini, Sebastian; Marverti, Gaetano; Zanocco-Marani, Tommaso; Davalli, Pierpaola; Guardavaccaro, Daniele; Mai, Sabine; Caporali, Andrea; D’Arca, Domenico
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth
2021-01-01 Tagliazucchi, Lorenzo; Malpezzi, Giulia; Pozzi, Cecilia; Lopresti, Ludovica; Venturelli, Alberto; D'Arca, Domenico; Marverti, Gaetano; Cecconi, Ciro; Ponterini, Glauco; Costi, Maria Paola
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
2022-01-01 Costantino, Luca; Ferrari, Stefania; Santucci, Matteo; MH Salo-Ahen, Outi; Carosati, Emanuele; Franchini, Silvia; Lauriola, Angela; Pozzi, Cecilia; Trande, Matteo; Gozzi, Gaia; Saxena, Puneet; Cannazza, Giuseppe; Losi, Lorena; Cardinale, Daniela; Venturelli, Alberto; Quotadamo, Antonio; Linciano, Pasquale; Tagliazucchi, Lorenzo; Moschella, MARIA GAETANA; Guerrini, Remo; Pacifico, Salvatore; Luciani, Rosaria; Genovese, Filippo; Henrich, Stefan; Alboni, Silvia; Santarem, Nuno; CORDEIRO DA SILVA, Anabela; Giovannetti, Elisa; J Peters, Godefridus; Pinton, Paolo; Rimessi, Alessandro; Cruciani, Gabriele; M Stroud, Robert; C Wade, Rebecca; Mangani, Stefano; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems
2022-01-01 Moschella, Mg; Marverti, G; Cassanelli, Valentina; Venuti, Federica; Tagliazucchi, L; Costi, Mp; D’Arca., D
Enhanced anti-hyperproliferative activity of human thymidylate synthase inhibitor peptide by solid lipid nanoparticle delivery
2015-01-01 Sacchetti, Francesca; Marraccini, Chiara; D'Arca, Domenico; Pela', Michela; Pinetti, Diego; Maretti, Eleonora; Hanuskova, Miriam; Iannuccelli, Valentina; Costi, Maria Paola; Leo, Eliana Grazia
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA
2023-01-01 Malpezzi, Giulia; Viander, Xavier; Zaltron, Annamaria; Neri, Benedetta; Di Felice, Giulia; Tagliazucchi, Lorenzo; Aiello, Daniele; Moschella, MARIA GAETANA; Costi, Maria Paola; D'Arca, Domenico; Cecconi, Ciro
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells | 1-gen-2020 | Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Francesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana Grazia; Costi, Maria Paola; D'Arca, Domenico | |
| A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties | 1-gen-2022 | Tagliazucchi, Lorenzo; Venturelli, Alberto; Malpezzi, Giulia; Moschella, MARIA GAETANA; Aiello, Daniele; Lopresti, Ludovica; Pozzi, Cecilia; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola | |
| Anticancer activity of green tea polyphenols in prostate gland | 1-gen-2012 | Davalli, Pierpaola; F., Rizzi; A., Caporali; D., Pellacani; S., Davoli; S., Bettuzzi; M., Brausi; D'Arca, Domenico | |
| ANTICANCER DRUGS | 1-gen-2015 | Costantino, Luca; Costi, Maria Paola; Ponterini, Glauco; Marverti, Gaetano; Franchini, Silvia; Tondi, Donatella; D'Arca, Domenico; Ferrari, Stefania; Luciani, Rosaria; Venturelli, Alberto; Sammak, Susan; Lauriola, Angela; Gozzi, Gaia | |
| Ca2+ depletion induces nuclear clusterin, a novel effector of apoptosis in immortalized human prostate cells | 1-gen-2005 | Ae, Caccamo; Scaltriti, Maurizio; A., Caporali; D'Arca, Domenico; Corti, Arnaldo; D., Corvetta; A., Sala; S., Bettuzzi | |
| Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin | 1-gen-2004 | Ae, Caccamo; Scaltriti, Maurizio; A., Caporali; D'Arca, Domenico; F., Scorcioni; Astancolle, Serenella; M., Mangiola; S., Bettuzzi | |
| Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme | 1-gen-2021 | Tagliazucchi, Lorenzo; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola | |
| Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer | 1-gen-2004 | Scaltriti, Maurizio; M., Brausi; A., Amorosi; A., Caporali; D'Arca, Domenico; Astancolle, Serenella; Corti, Arnaldo; S., Bettuzzi | |
| Clusterin decreases oxidative stress in lung fibroblasts exposed to cigarette smoke | 1-gen-2006 | Carnevali, S; Luppi, Fabrizio; D'Arca, Domenico; Caporali, A; Ruggieri, Mp; Vettori, Mv; Caglieri, A; Astancolle, Serenella; Panico, Francesca; Davalli, Pierpaola; Mutti, A; Fabbri, Leonardo; Corti, Arnaldo | |
| Clusterin gene expression is down-regulated in transformed epithelial cells but up-regulated in fibroblasts from prostate cancer | 1-gen-2003 | Bettuzzi, S; Scaltriti, M; Caporali, A; Brausi, M; Astancolle, S; D'Arca, D; Corti, A. | |
| Clusterin is down-regulated during the progression of prostate cancer in the tramp mouse model but up-regulated during chemioprevention by green tea catechins administration | 1-gen-2003 | Davalli, Pierpaola; Astancolle, Serenella; Caporali, A.; D'Arca, Domenico; Corti, Arnaldo; Brasi, M. B. | |
| Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth | 1-gen-2018 | Saxena, Puneet; Severi, Leda; Santucci, Matteo; Taddia, Laura; Ferrari, Stefania; Luciani, Rosaria; Marverti, Gaetano; Marraccini, Chiara; Tondi, Donatella; Mor, Marco; Laura, Scalvini; Vitiello, Simone; Losi, Lorena; Fonda, Sergio; Pacifico, Salvatore; Guerrini, Remo; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola | |
| Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? | 1-gen-2017 | Sacchetti, Francesca; D'Arca, Domenico; Genovese, Filippo; Pacifico, Salvatore; Maretti, Eleonora; Hanuskova, Miriam; Iannuccelli, Valentina; Costi, Maria Paola; Leo, Eliana Grazia | |
| Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth | 1-gen-2019 | Pacifico, Salvatore; Santucci, Matteo; Luciani, Rosaria; Saxena, Puneet; Linciano, Pasquale; Ponterini, Glauco; Lauriola, Angela; D'Arca, Domenico; Marverti, Gaetano; Guerrini, Remo; Costi, Maria Paola | |
| Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells | 1-gen-2020 | Lauriola, Angela; Martello, Andrea; Fantini, Sebastian; Marverti, Gaetano; Zanocco-Marani, Tommaso; Davalli, Pierpaola; Guardavaccaro, Daniele; Mai, Sabine; Caporali, Andrea; D’Arca, Domenico | |
| Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth | 1-gen-2021 | Tagliazucchi, Lorenzo; Malpezzi, Giulia; Pozzi, Cecilia; Lopresti, Ludovica; Venturelli, Alberto; D'Arca, Domenico; Marverti, Gaetano; Cecconi, Ciro; Ponterini, Glauco; Costi, Maria Paola | |
| Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth | 1-gen-2022 | Costantino, Luca; Ferrari, Stefania; Santucci, Matteo; MH Salo-Ahen, Outi; Carosati, Emanuele; Franchini, Silvia; Lauriola, Angela; Pozzi, Cecilia; Trande, Matteo; Gozzi, Gaia; Saxena, Puneet; Cannazza, Giuseppe; Losi, Lorena; Cardinale, Daniela; Venturelli, Alberto; Quotadamo, Antonio; Linciano, Pasquale; Tagliazucchi, Lorenzo; Moschella, MARIA GAETANA; Guerrini, Remo; Pacifico, Salvatore; Luciani, Rosaria; Genovese, Filippo; Henrich, Stefan; Alboni, Silvia; Santarem, Nuno; CORDEIRO DA SILVA, Anabela; Giovannetti, Elisa; J Peters, Godefridus; Pinton, Paolo; Rimessi, Alessandro; Cruciani, Gabriele; M Stroud, Robert; C Wade, Rebecca; Mangani, Stefano; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola | |
| Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems | 1-gen-2022 | Moschella, Mg; Marverti, G; Cassanelli, Valentina; Venuti, Federica; Tagliazucchi, L; Costi, Mp; D’Arca., D | |
| Enhanced anti-hyperproliferative activity of human thymidylate synthase inhibitor peptide by solid lipid nanoparticle delivery | 1-gen-2015 | Sacchetti, Francesca; Marraccini, Chiara; D'Arca, Domenico; Pela', Michela; Pinetti, Diego; Maretti, Eleonora; Hanuskova, Miriam; Iannuccelli, Valentina; Costi, Maria Paola; Leo, Eliana Grazia | |
| Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA | 1-gen-2023 | Malpezzi, Giulia; Viander, Xavier; Zaltron, Annamaria; Neri, Benedetta; Di Felice, Giulia; Tagliazucchi, Lorenzo; Aiello, Daniele; Moschella, MARIA GAETANA; Costi, Maria Paola; D'Arca, Domenico; Cecconi, Ciro |