PINZI, LUCA
PINZI, LUCA
Dipartimento di Scienze della Vita
2-Phenyloxazole-4-carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B
2019 Di Paolo, M. L.; Christodoulou, M. S.; Calogero, A. M.; Pinzi, L.; Rastelli, G.; Passarella, D.; Cappelletti, G.; Dalla Via, L.
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators
2016 Battisti, UMBERTO MARIA; Citti, Cinzia; Rastelli, Giulio; Pinzi, Luca; Puja, Giulia; Ravazzini, Federica; Ciccarella, Giuseppe; Braghiroli, Daniela; Cannazza, Giuseppe
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L.
2021 Brighenti, V.; Iseppi, R.; Pinzi, L.; Mincuzzi, A.; Ippolito, A.; Messi, P.; Sanzani, S. M.; Rastelli, G.; Pellati, F.
Chemoinformatics Analyses of Tau Ligands Reveal Key Molecular Requirements for the Identification of Potential Drug Candidates against Tauopathies
2021 Pinzi, Luca; Tinivella, Annachiara; Rastelli, Giulio
Computational polypharmacology comes of age
2015 Rastelli, Giulio; Pinzi, Luca
Design and Synthesis of Hsp90 Inhibitors with B-Raf and PDHK1 Multi-Target Activity
2021 Pinzi, L.; Foschi, F.; Christodoulou, M. S.; Passarella, D.; Rastelli, G.
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90
2020 Pinzi, L.; Benedetti, R.; Altucci, L.; Rastelli, G.
Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors
2023 Tinivella, Annachiara; Nwachukwu, J. C.; Angeli, A.; Foschi, F.; Benatti, Annalaura; Pinzi, Luca; Izard, T.; Ferraroni, M.; Erumbi, R.; Christodoulou, M. S.; Passarella, D.; Supuran, C.; Nettles, K. W.; Rastelli, Giulio
Development and application of LigAdvisor, a user-friendly web-platform for polypharmacology and drug repurposing
2021 Pinzi, Luca; Tinivella, Annachiara; Rastelli, Giulio
Development of machine learning classifers to predict compound activity on prostate cancer cell lines.
2022 Bonanni, Davide; Pinzi, Luca; Rastelli, Giulio
Development of machine learning classifiers to predict compound activity on prostate cancer cell lines
2022 Bonanni, Davide; Pinzi, Luca; Rastelli, Giulio
Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase
2023 Tinivella, A.; Banchi, M.; Gambacorta, G.; Borghi, F.; Orlandi, P.; Baxendale, I. R.; Di Paolo, A.; Bocci, G.; Pinzi, L.; Rastelli, G.
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer
2023 Moi, Davide; Bonanni, Davide; Belluti, Silvia; Linciano, Pasquale; Citarella, Andrea; Franchini, Silvia; Sorbi, Claudia; Imbriano, Carol; Pinzi, Luca; Rastelli, Giulio
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease
2021 Pinzi, Luca; Tinivella, Annachiara; Caporuscio, Fabiana; Rastelli, Giulio
Dual Targeting Strategies On Histone Deacetylase 6 (HDAC6) And Heat Shock Protein 90 (Hsp90)
2022 Bonanni, Davide; Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bergamini, Elisa; Rastelli, Giulio
Early Diagnosis of Neurodegenerative Diseases: What Has Been Undertaken to Promote the Transition from PET to Fluorescence Tracers
2024 Bisi, N.; Pinzi, L.; Rastelli, G.; Tonali, N.
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5
2019 Graziani, Davide; Caligari, Silvia; Callegari, Elisa; De Toma, Carlo; Longhi, Matteo; Frigerio, Fabio; Dilernia, Roberto; Menegon, Sergio; Pinzi, Luca; Pirona, Lorenza; Tazzari, Valerio; Valsecchi, Anna Elisa; Vistoli, Giulio; Rastelli, Giulio; Ruga Riva, Carlo
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space
2017 Anighoro, A.; Pinzi, Luca; Marverti, Gaetano; Bajorath, J; Rastelli, Giulio
How drug repurposing can advance drug discovery: challenges and opportunities
2024 Pinzi, Luca; Bisi, Nicolò; Rastelli, Giulio
Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications
2021 Citarella, A.; Moi, D.; Pinzi, L.; Bonanni, D.; Rastelli, G.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
2-Phenyloxazole-4-carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B | 1-gen-2019 | Di Paolo, M. L.; Christodoulou, M. S.; Calogero, A. M.; Pinzi, L.; Rastelli, G.; Passarella, D.; Cappelletti, G.; Dalla Via, L. | |
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators | 1-gen-2016 | Battisti, UMBERTO MARIA; Citti, Cinzia; Rastelli, Giulio; Pinzi, Luca; Puja, Giulia; Ravazzini, Federica; Ciccarella, Giuseppe; Braghiroli, Daniela; Cannazza, Giuseppe | |
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. | 1-gen-2021 | Brighenti, V.; Iseppi, R.; Pinzi, L.; Mincuzzi, A.; Ippolito, A.; Messi, P.; Sanzani, S. M.; Rastelli, G.; Pellati, F. | |
Chemoinformatics Analyses of Tau Ligands Reveal Key Molecular Requirements for the Identification of Potential Drug Candidates against Tauopathies | 1-gen-2021 | Pinzi, Luca; Tinivella, Annachiara; Rastelli, Giulio | |
Computational polypharmacology comes of age | 1-gen-2015 | Rastelli, Giulio; Pinzi, Luca | |
Design and Synthesis of Hsp90 Inhibitors with B-Raf and PDHK1 Multi-Target Activity | 1-gen-2021 | Pinzi, L.; Foschi, F.; Christodoulou, M. S.; Passarella, D.; Rastelli, G. | |
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 | 1-gen-2020 | Pinzi, L.; Benedetti, R.; Altucci, L.; Rastelli, G. | |
Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors | 1-gen-2023 | Tinivella, Annachiara; Nwachukwu, J. C.; Angeli, A.; Foschi, F.; Benatti, Annalaura; Pinzi, Luca; Izard, T.; Ferraroni, M.; Erumbi, R.; Christodoulou, M. S.; Passarella, D.; Supuran, C.; Nettles, K. W.; Rastelli, Giulio | |
Development and application of LigAdvisor, a user-friendly web-platform for polypharmacology and drug repurposing | 1-gen-2021 | Pinzi, Luca; Tinivella, Annachiara; Rastelli, Giulio | |
Development of machine learning classifers to predict compound activity on prostate cancer cell lines. | 1-gen-2022 | Bonanni, Davide; Pinzi, Luca; Rastelli, Giulio | |
Development of machine learning classifiers to predict compound activity on prostate cancer cell lines | 1-gen-2022 | Bonanni, Davide; Pinzi, Luca; Rastelli, Giulio | |
Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase | 1-gen-2023 | Tinivella, A.; Banchi, M.; Gambacorta, G.; Borghi, F.; Orlandi, P.; Baxendale, I. R.; Di Paolo, A.; Bocci, G.; Pinzi, L.; Rastelli, G. | |
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer | 1-gen-2023 | Moi, Davide; Bonanni, Davide; Belluti, Silvia; Linciano, Pasquale; Citarella, Andrea; Franchini, Silvia; Sorbi, Claudia; Imbriano, Carol; Pinzi, Luca; Rastelli, Giulio | |
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease | 1-gen-2021 | Pinzi, Luca; Tinivella, Annachiara; Caporuscio, Fabiana; Rastelli, Giulio | |
Dual Targeting Strategies On Histone Deacetylase 6 (HDAC6) And Heat Shock Protein 90 (Hsp90) | 1-gen-2022 | Bonanni, Davide; Citarella, Andrea; Moi, Davide; Pinzi, Luca; Bergamini, Elisa; Rastelli, Giulio | |
Early Diagnosis of Neurodegenerative Diseases: What Has Been Undertaken to Promote the Transition from PET to Fluorescence Tracers | 1-gen-2024 | Bisi, N.; Pinzi, L.; Rastelli, G.; Tonali, N. | |
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 | 1-gen-2019 | Graziani, Davide; Caligari, Silvia; Callegari, Elisa; De Toma, Carlo; Longhi, Matteo; Frigerio, Fabio; Dilernia, Roberto; Menegon, Sergio; Pinzi, Luca; Pirona, Lorenza; Tazzari, Valerio; Valsecchi, Anna Elisa; Vistoli, Giulio; Rastelli, Giulio; Ruga Riva, Carlo | |
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space | 1-gen-2017 | Anighoro, A.; Pinzi, Luca; Marverti, Gaetano; Bajorath, J; Rastelli, Giulio | |
How drug repurposing can advance drug discovery: challenges and opportunities | 1-gen-2024 | Pinzi, Luca; Bisi, Nicolò; Rastelli, Giulio | |
Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications | 1-gen-2021 | Citarella, A.; Moi, D.; Pinzi, L.; Bonanni, D.; Rastelli, G. |