The design and realization of an optical sensor for measuring haematic pH during extracorporeal circulation is presented. It consists of a chemical sensing element in contact with the blood, an interrogation optical head to externally probe the sensing element and the front-end electronics to acquire and process the information of interest. The fluorescein O-methacrylate 97% is used as the indicator. The developed system has been tested in-vitro and on an in-vivo animal model. It showed a linear behavior in the haematic range of interest with a mean error lower than 0.01 units of pH.
Haematic pH sensor for extracorporeal circulation / Ferrari, Luca; Fabbri, Paola; Rovati, Luigi; Pilati, Francesco. - In: PROGRESS IN BIOMEDICAL OPTICS AND IMAGING. - ISSN 1605-7422. - STAMPA. - 8214:(2012), pp. 82140E-82140E. (Intervento presentato al convegno Spie Photonic west tenutosi a S. Francisco, USA nel 22 January 2012) [10.1117/12.906562].
Haematic pH sensor for extracorporeal circulation
FABBRI, Paola;ROVATI, Luigi;PILATI, Francesco
2012
Abstract
The design and realization of an optical sensor for measuring haematic pH during extracorporeal circulation is presented. It consists of a chemical sensing element in contact with the blood, an interrogation optical head to externally probe the sensing element and the front-end electronics to acquire and process the information of interest. The fluorescein O-methacrylate 97% is used as the indicator. The developed system has been tested in-vitro and on an in-vivo animal model. It showed a linear behavior in the haematic range of interest with a mean error lower than 0.01 units of pH.
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