A bioactive glass called Biogran was implanted as granules of very narrow size range (300-355mm) in rabbit's dorsal muscles and in sheep's mandibular bone in order to determine the glass degratation in biological fluids and its influence on cellular function.Afert 1 month implantation in rabbit and 3 months in sheep , the granules with the surrounding tissue were resected and prepared for the optical and scanning electron microscopy.the results in dorsal muscle tissue showed tha the glass granules were uniformily surrounded by a highly cellular reactive tissue.In bone, granules were found extensively surrounded by bone tissue, in a almost-obliterated defect.
Galss corrosion layers on biactive glass granules of uniform size affect cellular function / Gatti, a. M.; Ducheyne, P.; Piattelli, A.; Schepers, E.; Trisi, P.; Chiarini, Luigi; Monari, Emanuela. - STAMPA. - (1993), pp. 395-400. (Intervento presentato al convegno 6th International Symposium on Ceramics in Medicine tenutosi a Philadelphia (USA) nel november 1993).
Galss corrosion layers on biactive glass granules of uniform size affect cellular function
CHIARINI, Luigi;MONARI, Emanuela
1993
Abstract
A bioactive glass called Biogran was implanted as granules of very narrow size range (300-355mm) in rabbit's dorsal muscles and in sheep's mandibular bone in order to determine the glass degratation in biological fluids and its influence on cellular function.Afert 1 month implantation in rabbit and 3 months in sheep , the granules with the surrounding tissue were resected and prepared for the optical and scanning electron microscopy.the results in dorsal muscle tissue showed tha the glass granules were uniformily surrounded by a highly cellular reactive tissue.In bone, granules were found extensively surrounded by bone tissue, in a almost-obliterated defect.
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