Inotropic effects of phenylephrine'-carbachol' and butyryrchorine were used in rabbit reft atrium to evaluate respectively, apha receptor blocking, muscarinic blocking and nicotinic blocking effect of tetramine disulfide. The alpha adrenergic blocking potency of newly synthetized derivatives were similar to those with an o-methoxy-benzyl group. Muscarinic and nicotinic blocking potency were correlated with the alpha adrenergic blocking potency.
Irreversible alfa-adrenoceptor blocking effects and irreversible muscarinic blocking and nicotinic blocking effect of tetramine disulfides on heart B. G. Benfey, B. Belleau, L. Brasili, M. Giannella, C. Melchiorre / B. G., Benfey; B., Belleau; Brasili, Livio; M., Giannella; C., Melchiorre. - In: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. - ISSN 0008-4212. - STAMPA. - 58:(1980), pp. 1477-1483.
Irreversible alfa-adrenoceptor blocking effects and irreversible muscarinic blocking and nicotinic blocking effect of tetramine disulfides on heart B. G. Benfey, B. Belleau, L. Brasili, M. Giannella, C. Melchiorre
BRASILI, Livio;
1980
Abstract
Inotropic effects of phenylephrine'-carbachol' and butyryrchorine were used in rabbit reft atrium to evaluate respectively, apha receptor blocking, muscarinic blocking and nicotinic blocking effect of tetramine disulfide. The alpha adrenergic blocking potency of newly synthetized derivatives were similar to those with an o-methoxy-benzyl group. Muscarinic and nicotinic blocking potency were correlated with the alpha adrenergic blocking potency.Pubblicazioni consigliate
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