Tuberculous myocarditis is a rare finding. We present the case of a 33-year-old woman who was in good health and who died suddenly at home. Autopsy and histopathologic examinations revealed granulamatous lesions in the myocardium, lungs, lymph nodes, liver, and spleen. No fast acid bacilli were demonstrated on histological examination. The presence of a Mycobacterium tuberculosis DNA complex was identified using a polymerase chain reaction (PCR) on formalin-fixed paraffin-embedded histological samples. An HIV test carried out on the blood obtained during the autopsy was negative according to the DNA amplification technique (PCR) and enzyme-linked immunosorbent assay serological test. We hypothesize that the mechanism of death was severe ventricular arrhythmia due to granulomatous proliferation in the structures of the interventricular septum.

Sudden death from tubercular myocarditis / Silingardi, Enrico; Rivasi, Francesco; Santunione, Anna Laura; Garagnani, Lorella. - In: JOURNAL OF FORENSIC SCIENCES. - ISSN 0022-1198. - STAMPA. - 51 (3)(2006), pp. 667-669.

Sudden death from tubercular myocarditis

SILINGARDI, Enrico;RIVASI, Francesco;SANTUNIONE, Anna Laura;GARAGNANI, Lorella
2006

Abstract

Tuberculous myocarditis is a rare finding. We present the case of a 33-year-old woman who was in good health and who died suddenly at home. Autopsy and histopathologic examinations revealed granulamatous lesions in the myocardium, lungs, lymph nodes, liver, and spleen. No fast acid bacilli were demonstrated on histological examination. The presence of a Mycobacterium tuberculosis DNA complex was identified using a polymerase chain reaction (PCR) on formalin-fixed paraffin-embedded histological samples. An HIV test carried out on the blood obtained during the autopsy was negative according to the DNA amplification technique (PCR) and enzyme-linked immunosorbent assay serological test. We hypothesize that the mechanism of death was severe ventricular arrhythmia due to granulomatous proliferation in the structures of the interventricular septum.
51 (3)
667
669
Sudden death from tubercular myocarditis / Silingardi, Enrico; Rivasi, Francesco; Santunione, Anna Laura; Garagnani, Lorella. - In: JOURNAL OF FORENSIC SCIENCES. - ISSN 0022-1198. - STAMPA. - 51 (3)(2006), pp. 667-669.
Silingardi, Enrico; Rivasi, Francesco; Santunione, Anna Laura; Garagnani, Lorella
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/612098
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