The newly synthesized triazole, 1-amino-6-methyl-4-phenylpyrazolo [3,4-d]-1,2,3-triazole (V5), was tested on the dermatophyte Trichophyton rubrum. Optical and electron microscopy showed that the treatment suppressed the various forms of saprophytic conidia, induced the formation of resistant spores (chlamidospores) and accelerated the formation of parasitic conidia (arthroconidia). In conclusion, this new triazole did not reveal any fungistatic or fungicidal activity and could not be considered as an antifungal substance. On the contrary, it stimulated the development of resistant and parasitic forms of spores.

Alterations in spore productions in Trichophyton rubrum treated “in vitro” with 1-amino-6-methyl-4-phenylpyrazolo-[3,4-d]-1,2,3,triazole / Mares, D; Romagnoli, Carlo; Sacchetti, G; Vicentini, C. B. AND BRUNI A.. - In: MYCOSES. - ISSN 0933-7407. - STAMPA. - 42(1999), pp. 549-554.

I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Powered by IRIS-about IRIS-Utilizzo dei cookie

 Copyright © 2022