The parental origin of the de novo deleted chromosome 4 was studied in five cases of Wolf-Hirschhorn syndrome using polymorphic probes mapping in the 4p16.3 region. In all the patients the deleted chromosome was found to be of paternal origin and these results, together with similar ones obtained by another group, make the preferential paternal origin of the de novo chromosome 4 deletion highly significant.

Paternal origin of the denovo deleted chromosome 4 in wolf-Hirschborn syndrome / Tupler, Rossella; L. B. o. r. t. o. t. t. o., .; E. M., Buhler; M., Alkan; N. J., Malik; N., Bosch Al Jadooa; L., Memo; P., Maraschio. - In: JOURNAL OF MEDICAL GENETICS. - ISSN 0022-2593. - STAMPA. - 29:(1992), pp. 53-55.

Paternal origin of the denovo deleted chromosome 4 in wolf-Hirschborn syndrome

TUPLER, Rossella;
1992

Abstract

The parental origin of the de novo deleted chromosome 4 was studied in five cases of Wolf-Hirschhorn syndrome using polymorphic probes mapping in the 4p16.3 region. In all the patients the deleted chromosome was found to be of paternal origin and these results, together with similar ones obtained by another group, make the preferential paternal origin of the de novo chromosome 4 deletion highly significant.
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Paternal origin of the denovo deleted chromosome 4 in wolf-Hirschborn syndrome / Tupler, Rossella; L. B. o. r. t. o. t. t. o., .; E. M., Buhler; M., Alkan; N. J., Malik; N., Bosch Al Jadooa; L., Memo; P., Maraschio. - In: JOURNAL OF MEDICAL GENETICS. - ISSN 0022-2593. - STAMPA. - 29:(1992), pp. 53-55.
Tupler, Rossella; L. B. o. r. t. o. t. t. o., .; E. M., Buhler; M., Alkan; N. J., Malik; N., Bosch Al Jadooa; L., Memo; P., Maraschio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/459470
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