AbstractThe NMR study on the interaction of Pt(II) with Amadori compounds is performed. The Amadori compounds are derived from the reaction of β-d-glucose with l-cystine leading to N,N′-di-(1-deoxy-β-fructos-1-yl)-l-cystine [FruCyscys], and with l-methionine leading to N-(1-deoxy-β-fructos-1-yl)-l-methionine [FruMet].The great instability of 2-(1,2,3,4,5-pentahydroxypentyl)-1,3-thiazolidine-4-carboxylic acid [GlcCys], formed by the condensation reaction of β-d-glucose and l-cysteine, prevents the formation of its Pt(II) complexes. Differently, FruMet well reacts with K2PtCl4 in 1:1 M/L molar ratio leading to the formation of [Pt(FruMet-N,S)Cl2], in which the Amadori compound coordinates the metal ion through nitrogen and sulphur atoms. FruMet originates also a solid trans complex [Pt(FruMet-N,S)2]Cl2. Its NMR solution study allowed to identify two isomers with respect to nitrogen and sulphur atoms: R,R and S,S.In [Pt2FruCyscysCl4] species, FruCyscys molecule links two Pt(II) ions giving rise to two pentaatomic N,S-chelate rings.

1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds / Ferrari, Erika; Grandi, Romano; Lazzari, Sandra; Marverti, Gaetano; Rossi, Cecilia; Saladini, Monica. - In: POLYHEDRON. - ISSN 0277-5387. - STAMPA. - 26:15(2007), pp. 4045-4052. [10.1016/j.poly.2007.05.001]

1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds

FERRARI, Erika;GRANDI, Romano;LAZZARI, Sandra;MARVERTI, Gaetano;ROSSI, Cecilia;SALADINI, Monica
2007

Abstract

AbstractThe NMR study on the interaction of Pt(II) with Amadori compounds is performed. The Amadori compounds are derived from the reaction of β-d-glucose with l-cystine leading to N,N′-di-(1-deoxy-β-fructos-1-yl)-l-cystine [FruCyscys], and with l-methionine leading to N-(1-deoxy-β-fructos-1-yl)-l-methionine [FruMet].The great instability of 2-(1,2,3,4,5-pentahydroxypentyl)-1,3-thiazolidine-4-carboxylic acid [GlcCys], formed by the condensation reaction of β-d-glucose and l-cysteine, prevents the formation of its Pt(II) complexes. Differently, FruMet well reacts with K2PtCl4 in 1:1 M/L molar ratio leading to the formation of [Pt(FruMet-N,S)Cl2], in which the Amadori compound coordinates the metal ion through nitrogen and sulphur atoms. FruMet originates also a solid trans complex [Pt(FruMet-N,S)2]Cl2. Its NMR solution study allowed to identify two isomers with respect to nitrogen and sulphur atoms: R,R and S,S.In [Pt2FruCyscysCl4] species, FruCyscys molecule links two Pt(II) ions giving rise to two pentaatomic N,S-chelate rings.
26
15
4045
4052
1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds / Ferrari, Erika; Grandi, Romano; Lazzari, Sandra; Marverti, Gaetano; Rossi, Cecilia; Saladini, Monica. - In: POLYHEDRON. - ISSN 0277-5387. - STAMPA. - 26:15(2007), pp. 4045-4052. [10.1016/j.poly.2007.05.001]
Ferrari, Erika; Grandi, Romano; Lazzari, Sandra; Marverti, Gaetano; Rossi, Cecilia; Saladini, Monica
File in questo prodotto:
File Dimensione Formato  
Polyhedron_2007_26_4045.pdf

non disponibili

Tipologia: Post-print dell'autore (bozza post referaggio)
Dimensione 719.87 kB
Formato Adobe PDF
719.87 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/309813
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 11
social impact