Taurohyodeoxycholic acid and tauroursodeoxycholic acid were infused intraduodenally at a rate of 0.8 gk for three hours in 3 cholecystectomized T-tube patients, Biliary lipid secretion and bile acid composition were evaluated before and after replacement of the endogenous bile acid pool with the two bile acids. As compared to basal values (2.78+/-1.67 mM/l), taurohyodeoxycholic acid induced a greater increase in the biliary concentration of phospholipids (4.12+/-1.23 mM/l) as compared to tauroursodeoxycholic acid (3.14+/-0.98 mM/l). Biliary cholesterol concentration after taurohyodeoxycholic acid (1.89+/-0.63 mM/l) was unchanged as compared to the pretreatment period (1.98+/-0.58 mM/l), while it decreased significantly after tauroursodeoxycholic acid (0.85+/-0.08 mM/l). Biliary cholesterol secreted per unit of bile acid was greater during taurohyodeoxycholic acid than during tauroursodeoxycholic acid, while the opposite was observed for the secretion of phospholipids.

Effect of taurohyodeoxycholic acid on biliary lipid secretion in man: preliminary report / Loria, Paola; M., Bozzoli; M., Angelico; Bertolotti, Marco; Carubbi, Francesca; M., Concari; L., Baiocchi; A., Nistri; P., Della Guardia; M., Romani; Carulli, Nicola. - In: ITALIAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0392-0623. - ELETTRONICO. - 28:(1996), pp. 391-392.

Effect of taurohyodeoxycholic acid on biliary lipid secretion in man: preliminary report.

LORIA, Paola;BERTOLOTTI, Marco;CARUBBI, Francesca;CARULLI, Nicola
1996

Abstract

Taurohyodeoxycholic acid and tauroursodeoxycholic acid were infused intraduodenally at a rate of 0.8 gk for three hours in 3 cholecystectomized T-tube patients, Biliary lipid secretion and bile acid composition were evaluated before and after replacement of the endogenous bile acid pool with the two bile acids. As compared to basal values (2.78+/-1.67 mM/l), taurohyodeoxycholic acid induced a greater increase in the biliary concentration of phospholipids (4.12+/-1.23 mM/l) as compared to tauroursodeoxycholic acid (3.14+/-0.98 mM/l). Biliary cholesterol concentration after taurohyodeoxycholic acid (1.89+/-0.63 mM/l) was unchanged as compared to the pretreatment period (1.98+/-0.58 mM/l), while it decreased significantly after tauroursodeoxycholic acid (0.85+/-0.08 mM/l). Biliary cholesterol secreted per unit of bile acid was greater during taurohyodeoxycholic acid than during tauroursodeoxycholic acid, while the opposite was observed for the secretion of phospholipids.
28
391
392
Effect of taurohyodeoxycholic acid on biliary lipid secretion in man: preliminary report / Loria, Paola; M., Bozzoli; M., Angelico; Bertolotti, Marco; Carubbi, Francesca; M., Concari; L., Baiocchi; A., Nistri; P., Della Guardia; M., Romani; Carulli, Nicola. - In: ITALIAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0392-0623. - ELETTRONICO. - 28:(1996), pp. 391-392.
Loria, Paola; M., Bozzoli; M., Angelico; Bertolotti, Marco; Carubbi, Francesca; M., Concari; L., Baiocchi; A., Nistri; P., Della Guardia; M., Romani; Carulli, Nicola
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/309677
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