Background: Ovarian cancer is metastatic at presentation in about 62% of cases, but brain metastases are rare, reported in 3.3–4% of patients. Brain metastasis seems to be more frequent in advanced stages at diagnosis and in patients with BRCA1/2 mutation. Case presentation: We present a case of a 47-year-old Caucasian woman, BRCA wild type, with an ovarian cancer that started with single cerebellar metastasis. Conclusion: Brain metastases in ovarian cancer are rare and complex for diagnosis and management. This case focuses both on diagnosis and treatment, emphasizing the importance of a multimodal approach in a multidisciplinary team.
Cerebellar metastasis of ovarian cancer: a case report / Cabitza, E.; Pirola, M.; Baldessari, C.; Bernardelli, G.; Zunarelli, E.; Pipitone, S.; Vitale, M. G.; Nasso, C.; Molinaro, E.; Oltrecolli, M.; D'Agostino, E.; Mandato, V. D.; Palicelli, A.; Dominici, M.; Sabbatini, R.. - In: JOURNAL OF MEDICAL CASE REPORTS. - ISSN 1752-1947. - 17:1(2023), pp. 553-558. [10.1186/s13256-023-04211-6]
Cerebellar metastasis of ovarian cancer: a case report
Cabitza E.;Baldessari C.;Pipitone S.;Nasso C.;Molinaro E.;Oltrecolli M.;D'Agostino E.;Dominici M.;
2023
Abstract
Background: Ovarian cancer is metastatic at presentation in about 62% of cases, but brain metastases are rare, reported in 3.3–4% of patients. Brain metastasis seems to be more frequent in advanced stages at diagnosis and in patients with BRCA1/2 mutation. Case presentation: We present a case of a 47-year-old Caucasian woman, BRCA wild type, with an ovarian cancer that started with single cerebellar metastasis. Conclusion: Brain metastases in ovarian cancer are rare and complex for diagnosis and management. This case focuses both on diagnosis and treatment, emphasizing the importance of a multimodal approach in a multidisciplinary team.
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