Atypical pigmented facial lesions (aPFLs)-including lentigo maligna (LM) and lentigo maligna melanoma (LMM), solar lentigo (SL), pigmented actinic keratosis (PAK), atypical nevi (AN), seborrheic keratosis (SK) and lichen planus-like keratosis (LPLK)-can exhibit clinical and dermoscopic overlapping features. We aimed to investigate if and how 14 dermoscopic features suggestive for the aforementioned aPFLs vary according to six facial sites among 1197 aPFLs cases (excised to rule out malignancy) along with lesion and patients' metadata. According to distribution and association analysis, aPFLs on the forehead of a male patient aged > 69 years displaying the obliterated follicular openings pattern, appear to be more at risk of malignancy. Of converse, aPFLs of the orbital/cheek/nose area with evident and regular follicular openings with diameter < 10 mm in a female aged below 68 are probably benign. The obliterated follicular openings, keratin plugs, evident and regular follicular openings and target-like pattern features differed significantly among six facial areas in all aPFLs cases. Lesion of the nose may show both features suggestive of malignancy and benignity (e.g. many SL and PAK may display target-like pattern and some LM/LMM cases display keratin plugs and evident and follicular openings), making these features less specific.

Dermoscopy of atypical pigmented lesions of the face: Variation according to facial areas / Tognetti, Linda; Cartocci, Alessandra; Cinotti, Elisa; D'Onghia, Martina; Żychowska, Magdalena; Moscarella, Elvira; Dika, Emi; Farnetani, Francesca; Guida, Stefania; Paoli, John; Lallas, Aimilios; Tiodorovic, Danica; Stanganelli, Ignazio; Longo, Caterina; Suppa, Mariano; Zalaudek, Iris; Argenziano, Giuseppe; Perrot, Jean Luc; Rubegni, Giovanni; Cataldo, Gennaro; Rubegni, Pietro. - In: EXPERIMENTAL DERMATOLOGY. - ISSN 0906-6705. - 32:12(2023), pp. 2166-2172. [10.1111/exd.14941]

Dermoscopy of atypical pigmented lesions of the face: Variation according to facial areas

Moscarella, Elvira;Farnetani, Francesca;Guida, Stefania;Longo, Caterina;
2023

Abstract

Atypical pigmented facial lesions (aPFLs)-including lentigo maligna (LM) and lentigo maligna melanoma (LMM), solar lentigo (SL), pigmented actinic keratosis (PAK), atypical nevi (AN), seborrheic keratosis (SK) and lichen planus-like keratosis (LPLK)-can exhibit clinical and dermoscopic overlapping features. We aimed to investigate if and how 14 dermoscopic features suggestive for the aforementioned aPFLs vary according to six facial sites among 1197 aPFLs cases (excised to rule out malignancy) along with lesion and patients' metadata. According to distribution and association analysis, aPFLs on the forehead of a male patient aged > 69 years displaying the obliterated follicular openings pattern, appear to be more at risk of malignancy. Of converse, aPFLs of the orbital/cheek/nose area with evident and regular follicular openings with diameter < 10 mm in a female aged below 68 are probably benign. The obliterated follicular openings, keratin plugs, evident and regular follicular openings and target-like pattern features differed significantly among six facial areas in all aPFLs cases. Lesion of the nose may show both features suggestive of malignancy and benignity (e.g. many SL and PAK may display target-like pattern and some LM/LMM cases display keratin plugs and evident and follicular openings), making these features less specific.
2023
32
12
2166
2172
Dermoscopy of atypical pigmented lesions of the face: Variation according to facial areas / Tognetti, Linda; Cartocci, Alessandra; Cinotti, Elisa; D'Onghia, Martina; Żychowska, Magdalena; Moscarella, Elvira; Dika, Emi; Farnetani, Francesca; Guida, Stefania; Paoli, John; Lallas, Aimilios; Tiodorovic, Danica; Stanganelli, Ignazio; Longo, Caterina; Suppa, Mariano; Zalaudek, Iris; Argenziano, Giuseppe; Perrot, Jean Luc; Rubegni, Giovanni; Cataldo, Gennaro; Rubegni, Pietro. - In: EXPERIMENTAL DERMATOLOGY. - ISSN 0906-6705. - 32:12(2023), pp. 2166-2172. [10.1111/exd.14941]
Tognetti, Linda; Cartocci, Alessandra; Cinotti, Elisa; D'Onghia, Martina; Żychowska, Magdalena; Moscarella, Elvira; Dika, Emi; Farnetani, Francesca; G...espandi
File in questo prodotto:
File Dimensione Formato  
Experimental Dermatology - 2023 - Tognetti - Dermoscopy of atypical pigmented lesions of the face Variation according to.pdf

Open access

Tipologia: Versione pubblicata dall'editore
Dimensione 1.02 MB
Formato Adobe PDF
1.02 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1321467
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 3
social impact