Manganese (Mn) is an essential metal that can become neurotoxic at elevated levels with negative consequences on neurodevelopment. We have evaluated the influence of single nucleotide polymorphisms (SNPs) in Mn transporter genes SLC30A10 and SLC39A8 on Mn concentrations in dentine, a validated biomarker that reflects Mn tissue concentrations early in life.

Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth / Wahlberg, Karin; Arora, Manish; Curtin, Austen; Curtin, Paul; Wright, Robert O; Smith, Donald R; Lucchini, Roberto; Broberg, Karin; Austin, Christine. - In: NEUROTOXICOLOGY. - ISSN 0161-813X. - 64:(2018), pp. 103-109. [10.1016/j.neuro.2017.09.003]

Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth

LUCCHINI, Roberto;
2018

Abstract

Manganese (Mn) is an essential metal that can become neurotoxic at elevated levels with negative consequences on neurodevelopment. We have evaluated the influence of single nucleotide polymorphisms (SNPs) in Mn transporter genes SLC30A10 and SLC39A8 on Mn concentrations in dentine, a validated biomarker that reflects Mn tissue concentrations early in life.
2018
13-set-2017
64
103
109
Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth / Wahlberg, Karin; Arora, Manish; Curtin, Austen; Curtin, Paul; Wright, Robert O; Smith, Donald R; Lucchini, Roberto; Broberg, Karin; Austin, Christine. - In: NEUROTOXICOLOGY. - ISSN 0161-813X. - 64:(2018), pp. 103-109. [10.1016/j.neuro.2017.09.003]
Wahlberg, Karin; Arora, Manish; Curtin, Austen; Curtin, Paul; Wright, Robert O; Smith, Donald R; Lucchini, Roberto; Broberg, Karin; Austin, Christine
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1318840
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