Here we report on a bioresorbable fluorescence sensor for in vivo pH monitoring. The sensor leverages a nanometer-thick multilayer stack of polyelectrolytes labelled with a pH-insensitive fluorophore conformably deposited within a porous silica membrane-thickness of a few micrometers-to increase fluorescence intensity up to 600 times and enable reliable measurements through skin.
Implantable and Bioresorbable Nanostructured Fluorescence Sensor for In vivo pH Monitoring / Corsi, M.; Paghi, A.; Mariani, S.; Golinelli, G.; Debrassi, A.; Egri, G.; Leo, G.; Vandini, E.; Vilella, A.; Dahne, L.; Giuliani, D.; Barillaro, G.. - 2022-October:(2022), pp. 1-4. (Intervento presentato al convegno 2022 IEEE Sensors Conference, SENSORS 2022 tenutosi a Dallas nel 30 ottobre - 2 novembre 2022) [10.1109/SENSORS52175.2022.9967304].
Implantable and Bioresorbable Nanostructured Fluorescence Sensor for In vivo pH Monitoring
Corsi M.;Golinelli G.;Leo G.;Vandini E.;Vilella A.;Giuliani D.;
2022
Abstract
Here we report on a bioresorbable fluorescence sensor for in vivo pH monitoring. The sensor leverages a nanometer-thick multilayer stack of polyelectrolytes labelled with a pH-insensitive fluorophore conformably deposited within a porous silica membrane-thickness of a few micrometers-to increase fluorescence intensity up to 600 times and enable reliable measurements through skin.
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