The purpose of this study was to investigate short-time metabolic variations related to continuous epileptic activity elicited by fixation-off sensitivity (FOS). Time-resolved magnetic resonance spectroscopy was performed on a patient on whom previous clinical findings clearly indicated presence of FOS. The epileptic focus was localized with a simultaneous electroencephalographic and functional magnetic resonance imaging study. The results showed a linear increase of the sum of glutamate and glutamine with time of paroxysmal activity in epileptic focus and much greater concentration of choline-containing compounds in focus than in the contralateral side. © 2006 Elsevier Inc. All rights reserved.

Metabolic alteration transients during paroxysmal activity in an epileptic patient with fixation-off sensitivity: a case study / Giove, Federico; Garreffa, Girolamo; Peca, Stefano; Carní, Marco; Macrì, Maria Antonietta; Di Bonaventura, Carlo; Vaudano, Anna Elisabetta; Giallonardo, Anna Teresa; Prencipe, Massimiliano; Bozzao, Luigi; Pantano, Patrizia; Colonnese, Claudio; Maraviglia, Bruno. - In: MAGNETIC RESONANCE IMAGING. - ISSN 0730-725X. - 24:4(2006), pp. 373-379. [10.1016/j.mri.2005.11.003]

Metabolic alteration transients during paroxysmal activity in an epileptic patient with fixation-off sensitivity: a case study

VAUDANO, Anna Elisabetta;
2006

Abstract

The purpose of this study was to investigate short-time metabolic variations related to continuous epileptic activity elicited by fixation-off sensitivity (FOS). Time-resolved magnetic resonance spectroscopy was performed on a patient on whom previous clinical findings clearly indicated presence of FOS. The epileptic focus was localized with a simultaneous electroencephalographic and functional magnetic resonance imaging study. The results showed a linear increase of the sum of glutamate and glutamine with time of paroxysmal activity in epileptic focus and much greater concentration of choline-containing compounds in focus than in the contralateral side. © 2006 Elsevier Inc. All rights reserved.
24
4
373
379
Metabolic alteration transients during paroxysmal activity in an epileptic patient with fixation-off sensitivity: a case study / Giove, Federico; Garreffa, Girolamo; Peca, Stefano; Carní, Marco; Macrì, Maria Antonietta; Di Bonaventura, Carlo; Vaudano, Anna Elisabetta; Giallonardo, Anna Teresa; Prencipe, Massimiliano; Bozzao, Luigi; Pantano, Patrizia; Colonnese, Claudio; Maraviglia, Bruno. - In: MAGNETIC RESONANCE IMAGING. - ISSN 0730-725X. - 24:4(2006), pp. 373-379. [10.1016/j.mri.2005.11.003]
Giove, Federico; Garreffa, Girolamo; Peca, Stefano; Carní, Marco; Macrì, Maria Antonietta; Di Bonaventura, Carlo; Vaudano, Anna Elisabetta; Giallonardo, Anna Teresa; Prencipe, Massimiliano; Bozzao, Luigi; Pantano, Patrizia; Colonnese, Claudio; Maraviglia, Bruno
File in questo prodotto:
File Dimensione Formato  
GIOVE-MRI-2006.pdf

non disponibili

Dimensione 173.26 kB
Formato Adobe PDF
173.26 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1268298
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact