Foot-shock produced a more than 2-fold increase in noradrenaline (NA) release from the frontal cortex of freely moving rats. The effect of acute stress was almost completely prevented by the administration of diazepam (5 mg/kg i.p.). Diazepam alone inhibited cortical NA release, the maximal inhibition (-57%) being observed 90 min after the injection. Cortical NA release therefore appears to be a reliable index of central noradrenergic activity in response to stressful conditions. © 1990.

Stress increases noradrenaline release in the rat frontal cortex: Prevention by diazepam / Rossetti, Z. L.; Portas, C.; Pani, L.; Carboni, S.; Gessa, G. L.. - In: EUROPEAN JOURNAL OF PHARMACOLOGY. - ISSN 0014-2999. - 176:2(1990), pp. 229-231. [10.1016/0014-2999(90)90533-C]

Stress increases noradrenaline release in the rat frontal cortex: Prevention by diazepam

Pani L.;Carboni S.;
1990

Abstract

Foot-shock produced a more than 2-fold increase in noradrenaline (NA) release from the frontal cortex of freely moving rats. The effect of acute stress was almost completely prevented by the administration of diazepam (5 mg/kg i.p.). Diazepam alone inhibited cortical NA release, the maximal inhibition (-57%) being observed 90 min after the injection. Cortical NA release therefore appears to be a reliable index of central noradrenergic activity in response to stressful conditions. © 1990.
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Stress increases noradrenaline release in the rat frontal cortex: Prevention by diazepam / Rossetti, Z. L.; Portas, C.; Pani, L.; Carboni, S.; Gessa, G. L.. - In: EUROPEAN JOURNAL OF PHARMACOLOGY. - ISSN 0014-2999. - 176:2(1990), pp. 229-231. [10.1016/0014-2999(90)90533-C]
Rossetti, Z. L.; Portas, C.; Pani, L.; Carboni, S.; Gessa, G. L.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1212100
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