Background: Alcohol use disorders have a prevalence of 10% among the population of the United States and Europe and are one of the most frequent causes of liver cirrhosis in the Western world. Currently, alcohol-related liver cirrhosis represents one of the most frequent indications to liver transplant (LT), both as independent cause or associated with hepatitis C virus or hepatitis B virus infections. Starting from 2014, a multidisciplinary team involving surgeons, gastroenterologists, clinical toxicologists, psychiatrists, and psychologists was developed within the Modena Liver Transplant Center. Methods: We retrospectively reviewed our prospectively maintained institutional database of liver transplants in order to identify cirrhotic patients eligible for LT with a diagnosis of alcohol use disorder. Results: A total of 756 liver transplants were performed at Policlinico University Hospital, University of Modena, and Reggio Emilia, MO, Italy, between November 2000 and November 2017; 102 patients who underwent LT were considered eligible for inclusion in the study. Conclusions: The multidisciplinary approach, together with blood, urinary, and hair tests, allows identification of early recurrences and improves survival. Further studies are necessary to understand how multidisciplinary teams can change the 6-month rule in patient selection.

Impact of a Multidisciplinary Team on Alcohol Recidivism and Survival After Liver Transplant for Alcoholic Disease / Magistri, P.; Marzi, L.; Guerzoni, S.; Vandelli, M.; Mereu, F.; Ascari, F.; Guidetti, C.; Tarantino, G.; Serra, V.; Guerrini, G. P.; Ballarin, R.; Moscara, M.; De Maria, N.; Villa, E.; Di Benedetto, F.. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 51:1(2019), pp. 187-189. [10.1016/j.transproceed.2018.02.212]

Impact of a Multidisciplinary Team on Alcohol Recidivism and Survival After Liver Transplant for Alcoholic Disease

Magistri P.;Marzi L.;Guerzoni S.;Vandelli M.;Mereu F.;Ascari F.;Guidetti C.;Tarantino G.;Serra V.;Guerrini G. P.;Ballarin R.;Moscara M.;Villa E.;Di Benedetto F.
2019

Abstract

Background: Alcohol use disorders have a prevalence of 10% among the population of the United States and Europe and are one of the most frequent causes of liver cirrhosis in the Western world. Currently, alcohol-related liver cirrhosis represents one of the most frequent indications to liver transplant (LT), both as independent cause or associated with hepatitis C virus or hepatitis B virus infections. Starting from 2014, a multidisciplinary team involving surgeons, gastroenterologists, clinical toxicologists, psychiatrists, and psychologists was developed within the Modena Liver Transplant Center. Methods: We retrospectively reviewed our prospectively maintained institutional database of liver transplants in order to identify cirrhotic patients eligible for LT with a diagnosis of alcohol use disorder. Results: A total of 756 liver transplants were performed at Policlinico University Hospital, University of Modena, and Reggio Emilia, MO, Italy, between November 2000 and November 2017; 102 patients who underwent LT were considered eligible for inclusion in the study. Conclusions: The multidisciplinary approach, together with blood, urinary, and hair tests, allows identification of early recurrences and improves survival. Further studies are necessary to understand how multidisciplinary teams can change the 6-month rule in patient selection.
30-giu-2018
51
1
187
189
Impact of a Multidisciplinary Team on Alcohol Recidivism and Survival After Liver Transplant for Alcoholic Disease / Magistri, P.; Marzi, L.; Guerzoni, S.; Vandelli, M.; Mereu, F.; Ascari, F.; Guidetti, C.; Tarantino, G.; Serra, V.; Guerrini, G. P.; Ballarin, R.; Moscara, M.; De Maria, N.; Villa, E.; Di Benedetto, F.. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 51:1(2019), pp. 187-189. [10.1016/j.transproceed.2018.02.212]
Magistri, P.; Marzi, L.; Guerzoni, S.; Vandelli, M.; Mereu, F.; Ascari, F.; Guidetti, C.; Tarantino, G.; Serra, V.; Guerrini, G. P.; Ballarin, R.; Moscara, M.; De Maria, N.; Villa, E.; Di Benedetto, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1200933
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