Variant angina, defined as spontaneous angina pectoris associated with transient ST-segment elevation, is usually caused by episodic coronary spasm. At present, coronary artery spasm is a reversible coronary stenosis that limits coronary blood flow under resting conditions. Prinzmetal first described this type of angina pectoris as a distinct entity in 1959.1 Although several hypotheses have been suggested, the precise mechanism for coronary vasospastic disease remains unclear. Natural history of variant angina is heterogeneous. In most of the cases, the prognosis is good; however, it can lead to myocardial infarction (MI), life-threatening ventricular arrhythmias, and sudden death
Spontaneous echocardiographic wall motion abnormalities in variant angina / Politi, Luigi; Monopoli, Daniel Enrique; Sgura, Fabio Alfredo; Rossi, Rosario; Bursi, Francesca; Modena, Maria Grazia. - In: CIRCULATION. - ISSN 0009-7322. - ELETTRONICO. - 118:1(2008), pp. e4-e6. [10.1161/CIRCULATIONAHA.107.759530]
Spontaneous echocardiographic wall motion abnormalities in variant angina
Politi, Luigi;Monopoli, Daniel Enrique;Rossi, Rosario;Bursi, Francesca;Modena, Maria Grazia
2008
Abstract
Variant angina, defined as spontaneous angina pectoris associated with transient ST-segment elevation, is usually caused by episodic coronary spasm. At present, coronary artery spasm is a reversible coronary stenosis that limits coronary blood flow under resting conditions. Prinzmetal first described this type of angina pectoris as a distinct entity in 1959.1 Although several hypotheses have been suggested, the precise mechanism for coronary vasospastic disease remains unclear. Natural history of variant angina is heterogeneous. In most of the cases, the prognosis is good; however, it can lead to myocardial infarction (MI), life-threatening ventricular arrhythmias, and sudden deathPubblicazioni consigliate
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