Drug Resistant Bacteria represent a global emergency, limiting the effective treatment of bacterial infections.The development of novel strategies fighting bacterial infections is strongly desirable. One such approach is a means of prolonging the lifespan of current antibiotics, namely, the development of antibiotic adjuvants, i.e. compounds that do not themselves kill bacteria but instead enhance the effect of an antibiotic. Adjuvants have potential application in a number of situations, with the most obvious being the case of formerly susceptible bacteria that have acquired resistance. Additionally, the relative infancy of the adjuvant approach means that there are likely a greater number of both undiscovered targets and previously unidentified chemical scaffolds.

New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics
 / Maso, Lorenzo; Bellio, Pierangelo; Linciano, Pasquale; D’Acunto, Maria; Celenza, Giuseppe; Tondi, Donatella; Cendron, Laura 
. - (2018). (Intervento presentato al convegno Proteine 2018 tenutosi a Verona nel 28- 30 Maggio 2018).

New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics


Linciano, Pasquale
Membro del Collaboration Group
;
Tondi Donatella
Conceptualization
;
2018

Abstract

Drug Resistant Bacteria represent a global emergency, limiting the effective treatment of bacterial infections.The development of novel strategies fighting bacterial infections is strongly desirable. One such approach is a means of prolonging the lifespan of current antibiotics, namely, the development of antibiotic adjuvants, i.e. compounds that do not themselves kill bacteria but instead enhance the effect of an antibiotic. Adjuvants have potential application in a number of situations, with the most obvious being the case of formerly susceptible bacteria that have acquired resistance. Additionally, the relative infancy of the adjuvant approach means that there are likely a greater number of both undiscovered targets and previously unidentified chemical scaffolds.
2018
Proteine 2018
Verona
28- 30 Maggio 2018
Maso, Lorenzo; Bellio, Pierangelo; Linciano, Pasquale; D’Acunto, Maria; Celenza, Giuseppe; Tondi, Donatella; Cendron, Laura 

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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1164142
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