This paper investigates the response of a nanoelectrode based capacitive biosensor to the presence of single and double strands of DNA/PNA. The expected admittance spectrum for an idealized system with cylindrical symmetry, where the biomolecule is represented by a simple dielectric and charged rod, is calculated over a broad frequency range extending from below to above the electrolyte’s dielectric relaxation cut-off frequency. DNA and PNA hybridization is also considered. The results provide indications on optimum detection conditions for admittance based DNA biosensors.
On the response of nanoelectrode capacitive biosensors to DNA and PNA strands / Pittino, Federico; Passerini, F; Palestri, Pierpaolo; Selmi, Luca; Widdershoven, F.. - STAMPA. - (2013), pp. 40-44. (Intervento presentato al convegno 2013 5th IEEE International Workshop on Advances in Sensors and Interfaces, IWASI 2013 tenutosi a Bari, ita nel June) [10.1109/IWASI.2013.6576088].
On the response of nanoelectrode capacitive biosensors to DNA and PNA strands
PALESTRI, Pierpaolo;SELMI, Luca;
2013
Abstract
This paper investigates the response of a nanoelectrode based capacitive biosensor to the presence of single and double strands of DNA/PNA. The expected admittance spectrum for an idealized system with cylindrical symmetry, where the biomolecule is represented by a simple dielectric and charged rod, is calculated over a broad frequency range extending from below to above the electrolyte’s dielectric relaxation cut-off frequency. DNA and PNA hybridization is also considered. The results provide indications on optimum detection conditions for admittance based DNA biosensors.File | Dimensione | Formato | |
---|---|---|---|
Pittino_IWASI2013.pdf
Accesso riservato
Dimensione
1.26 MB
Formato
Adobe PDF
|
1.26 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris