The presence of a variety of cytokine-like molecules (IL-1 alpha, IL-1 beta, IL-2, IL-6, TNF-alpha) in the hemocytes of two molluscs, i.e., Planorbarius corneus and Viviparus ater, is reported. These molecules are present only in hemocytes with phagocytic activity. These data, together with recent reports on the presence of cytokine-like molecules in other invertebrates, suggest that cytokines are important, ancestral and functionally conserved molecules.
PRESENCE OF SEVERAL CYTOKINE-LIKE MOLECULES IN MOLLUSCAN HEMOCYTES / Ottaviani, Enzo; Franchini, Antonella; Franceschi, C.. - In: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. - ISSN 0006-291X. - STAMPA. - 195:(1993), pp. 984-988.
PRESENCE OF SEVERAL CYTOKINE-LIKE MOLECULES IN MOLLUSCAN HEMOCYTES
OTTAVIANI, Enzo;FRANCHINI, Antonella;
1993
Abstract
The presence of a variety of cytokine-like molecules (IL-1 alpha, IL-1 beta, IL-2, IL-6, TNF-alpha) in the hemocytes of two molluscs, i.e., Planorbarius corneus and Viviparus ater, is reported. These molecules are present only in hemocytes with phagocytic activity. These data, together with recent reports on the presence of cytokine-like molecules in other invertebrates, suggest that cytokines are important, ancestral and functionally conserved molecules.
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