We read with interest the recent article by Shiozaki H, et al. (Bone Marrow Transplant 2014; 49: 102–109) reporting a case of donor cell leukemia (DCL) occurring in a patient who previously underwent cord blood (CB) transplantation for myelodysplastic syndrome and describing the clinical and biological differences between DCL arising after hematopoietic SCT (HSCT) from either CB or BM sources. We would like to comment on these issues, reporting an unusual case of DCL in a patient with a long history of acute promyelocytic leukemia (APL).
An unusual case of B-ALL occurring in a patient with acute promyelocytic leukemia in remission after two hematopoietic SCTs: whose are the leukemic cells? / Bigliardi, S; Morselli, M; Potenza, Leonardo; Bresciani, P; Cuoghi, A; Coluccio, Valeria; Riva, Giovanni; Paolini, Ambra; Fantuzzi, Valeria; Faglioni, Laura; Nasillo, Vincenzo; Messerotti, Andrea; Marasca, Roberto; Narni, Franco; Luppi, Mario; Forghieri, Fabio. - In: BONE MARROW TRANSPLANTATION. - ISSN 0268-3369. - STAMPA. - 49:(2014), pp. 1237-1238. [10.1038/bmt.2014.119]