Our results demonstrated an increase of ICAM-1 and esRAGE levels, suggesting a progression of endothelial dysfunction, in asymptomatic FH children and adolescents despite a diet-induced improvement in lipid metabolism. sM may be early indicators of vascular damage and, together with familial history of premature CVD, may help clinicians in identifying children at risk before CVD develops.
Impairment of inflammatory markers in children and adolescents with familial hypercholesterolaemia / Predieri, Barbara; Malmusi, Giovanni; Lucaccioni, Laura; Patianna, VIVIANA DORA; P., Bruzzi; Iughetti, Lorenzo. - In: HORMONE RESEARCH IN PAEDIATRICS. - ISSN 1663-2818. - STAMPA. - 80(S1):(2013), pp. 234-234. (Intervento presentato al convegno ESPE Meeting tenutosi a Milano nel 19-22/09/2013).
Impairment of inflammatory markers in children and adolescents with familial hypercholesterolaemia
PREDIERI, Barbara;Malmusi, Giovanni;Lucaccioni, Laura;PATIANNA, VIVIANA DORA;IUGHETTI, Lorenzo
2013
Abstract
Our results demonstrated an increase of ICAM-1 and esRAGE levels, suggesting a progression of endothelial dysfunction, in asymptomatic FH children and adolescents despite a diet-induced improvement in lipid metabolism. sM may be early indicators of vascular damage and, together with familial history of premature CVD, may help clinicians in identifying children at risk before CVD develops.
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