Sarcolipin (SLN) is a 31-amino acid proteolipid that regulates the activity of SERCA1 (ATP2A1), a fasttwitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase. Two alleles were identified by SSCP analysis in the 218 bp fragment of the porcine SLN gene. Mendelian segregation was confirmed in three-generation families of the PiGMaP Consortium. The DNA samples belonging to six threegeneration families of the PiGMaP Consortium were genotyped at the SLN locus obtaining 98 informative meiosis. Multipoint sex-averaged map of porcine chromosome 9, placed SLN between markers PPP2ARB and CRYAB (PPP2ARB± 24.7 cM ± SLN ± 3.1 cM ± CRYAB ±). This assignment confirms the physical mapping of the porcine SLN gene to chromosome9p24-(1/3p21) previously obtained
The porcine sarcolipin (SLN) gene: identification of an SNP and linkage mapping to chromosome 9 / Fontanesi, L; Davoli, R; Milc, Justyna Anna; Russo, V.. - In: ANIMAL GENETICS. - ISSN 0268-9146. - STAMPA. - 32:2(2001), pp. 109-110. [10.1046/j.1365-2052.2001.0700c.x]
The porcine sarcolipin (SLN) gene: identification of an SNP and linkage mapping to chromosome 9.
MILC, Justyna Anna;
2001
Abstract
Sarcolipin (SLN) is a 31-amino acid proteolipid that regulates the activity of SERCA1 (ATP2A1), a fasttwitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase. Two alleles were identified by SSCP analysis in the 218 bp fragment of the porcine SLN gene. Mendelian segregation was confirmed in three-generation families of the PiGMaP Consortium. The DNA samples belonging to six threegeneration families of the PiGMaP Consortium were genotyped at the SLN locus obtaining 98 informative meiosis. Multipoint sex-averaged map of porcine chromosome 9, placed SLN between markers PPP2ARB and CRYAB (PPP2ARB± 24.7 cM ± SLN ± 3.1 cM ± CRYAB ±). This assignment confirms the physical mapping of the porcine SLN gene to chromosome9p24-(1/3p21) previously obtained
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
