EnglishA new melted bioactive system containing gold nanoparticles (AuNPs) was prepared exploiting a post-synthesis thermal treatment that allows one to modify crystal phases and nature, shape and distribution of the gold species in the glass-ceramic matrix as evidenced by UV-visible spectroscopy, transmission electron microscopy and powder X-ray diffraction analysis. In human MG-63 osteoblasts the presence of Aun+ species caused an increase of lactate dehydrogenase leakage and malonyldialdehyde production, whereas Hench's Bioglass HAu-600-17 containing only AuNPs did not cause any effect. In addition, HAu-600-17 caused in vitro hydroxyapatite formation and an increase of specific surface area with a controlled release of gold species; this material is then suitable to be used as a model system for the controlled delivery of nanoparticles.
Gold-containing bioactive glasses: a solid-state synthesis to produce alternative biomaterials for bone implantations / V., Aina; G., Cerrato; G., Martra; L., Bergandi; C., Costamagna; D., Ghigo; Malavasi, Gianluca; Lusvardi, Gigliola; Menabue, Ledi. - In: JOURNAL OF THE ROYAL SOCIETY INTERFACE. - ISSN 1742-5689. - ELETTRONICO. - 10(2013), pp. 20121040-20121040.
| Data di pubblicazione: | 2013 |
| Titolo: | Gold-containing bioactive glasses: a solid-state synthesis to produce alternative biomaterials for bone implantations |
| Autore/i: | V., Aina; G., Cerrato; G., Martra; L., Bergandi; C., Costamagna; D., Ghigo; Malavasi, Gianluca; Lusvardi, Gigliola; Menabue, Ledi |
| Autore/i UNIMORE: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1098/rsif.2012.1040 |
| Rivista: | |
| Volume: | 10 |
| Pagina iniziale: | 20121040 |
| Pagina finale: | 20121040 |
| Codice identificativo ISI: | WOS:000316415600007 |
| Codice identificativo Scopus: | 2-s2.0-84881266161 |
| Codice identificativo Pubmed: | 23427096 |
| Citazione: | Gold-containing bioactive glasses: a solid-state synthesis to produce alternative biomaterials for bone implantations / V., Aina; G., Cerrato; G., Martra; L., Bergandi; C., Costamagna; D., Ghigo; Malavasi, Gianluca; Lusvardi, Gigliola; Menabue, Ledi. - In: JOURNAL OF THE ROYAL SOCIETY INTERFACE. - ISSN 1742-5689. - ELETTRONICO. - 10(2013), pp. 20121040-20121040. |
| Tipologia | Articolo su rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | |
|---|---|---|---|
| J. R. Soc. Interface-2013-Aina-.pdf | Versione dell'editore (versione pubblicata) | Administrator Richiedi una copia |
I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
Copyright © 2021