In this retrospective study we evaluated the prognostic impact of peripheral blood monocytosis in patients with T-cell non Hodgkin lymphomas with "aggressive-typically nodal presentation". In this dataset monocytes >0.8×10(9)/L had a strong and statistically significant negative impact on overall survival (OS). In univariate analysis several parameters, including age >60 years, advanced stage, bone marrow involvement, ECOG PS >1, high LDH level, monocytes >0.8×10(9)/L, hemoglobin<120g/L, albumin<35g/L) had a negative influence on outcome, but in multivariate analysis, monocytosis alone had a stronger association with poor OS.

Monocytosis has adverse prognostic significance and impacts survival in patients with T-cell lymphomas / Bari, Alessia; Tadmor, T.; Sacchi, Stefano; Marcheselli, L.; Liardo, ELIANA VALENTINA; Pozzi, Samantha; Luminari, Stefano; Baldini, L.; Marmiroli, Sandra; Federico, Massimo; Polliack, A.. - In: LEUKEMIA RESEARCH. - ISSN 0145-2126. - STAMPA. - 37 (6)(2013), pp. 619-623. [10.1016/j.leukres.2013.01.009]

Monocytosis has adverse prognostic significance and impacts survival in patients with T-cell lymphomas

BARI, Alessia;SACCHI, Stefano;LIARDO, ELIANA VALENTINA;POZZI, Samantha;LUMINARI, Stefano;MARMIROLI, Sandra;FEDERICO, Massimo;
2013

Abstract

In this retrospective study we evaluated the prognostic impact of peripheral blood monocytosis in patients with T-cell non Hodgkin lymphomas with "aggressive-typically nodal presentation". In this dataset monocytes >0.8×10(9)/L had a strong and statistically significant negative impact on overall survival (OS). In univariate analysis several parameters, including age >60 years, advanced stage, bone marrow involvement, ECOG PS >1, high LDH level, monocytes >0.8×10(9)/L, hemoglobin<120g/L, albumin<35g/L) had a negative influence on outcome, but in multivariate analysis, monocytosis alone had a stronger association with poor OS.
37 (6)
619
623
Monocytosis has adverse prognostic significance and impacts survival in patients with T-cell lymphomas / Bari, Alessia; Tadmor, T.; Sacchi, Stefano; Marcheselli, L.; Liardo, ELIANA VALENTINA; Pozzi, Samantha; Luminari, Stefano; Baldini, L.; Marmiroli, Sandra; Federico, Massimo; Polliack, A.. - In: LEUKEMIA RESEARCH. - ISSN 0145-2126. - STAMPA. - 37 (6)(2013), pp. 619-623. [10.1016/j.leukres.2013.01.009]
Bari, Alessia; Tadmor, T.; Sacchi, Stefano; Marcheselli, L.; Liardo, ELIANA VALENTINA; Pozzi, Samantha; Luminari, Stefano; Baldini, L.; Marmiroli, Sandra; Federico, Massimo; Polliack, A.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/927690
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