About 30% of the ovulation induction cycles in GIFT and FIVET programmes are cancelled due to an inadequate response of patients to gonadotropins and/or clomiphene citrate. GnRH agonist-gonadotropins and/or "pure" FSH combination has been successful in inducing ovulation in patients with a previous history of cycle cancellation and/or alterations in the menstrual cycles. In order to reduce the number of cycle cancellations and obtain more homogeneous oocytes, GnRH agonist-gonadotropins and/or "pure" FSH combination in all candidates for GIFT and FIVET has been recently hypothesised. The Authors report results obtained from GnRH agonist-"pure" FSH combination in 30 normally menstruating patients of the GIFT programme: in 93% of cases the harvested oocytes were preovulatory, in 27.6% of cycles and in 28.6% of the GIFTs respectively an ongoing pregnancy was obtained. While the results obtained must be considered preliminary, they nevertheless suggest that the use of a combination of GnRH-agonist "pure" FSH in all patients in the GIFT programme may be of real clinical validity.

Induction of ovulation for gamete intrafallopian transfer (GIFT) using a gonadotropin-releasing hormone agonist and "pure" FSH: results obtained in 30 normally menstruating women / LA SALA, Giovanni Battista; Cantarelli, M; Parolari, G; Dessanti, L; Dall'Asta, D; Torelli, Mg; Salvatore, V; Dotti, C; Cavalieri, S; Brai, L.. - In: ACTA EUROPAEA FERTILITATIS. - ISSN 0587-2421. - ELETTRONICO. - 19:(1988), pp. 159-165.

Induction of ovulation for gamete intrafallopian transfer (GIFT) using a gonadotropin-releasing hormone agonist and "pure" FSH: results obtained in 30 normally menstruating women.

LA SALA, Giovanni Battista;
1988

Abstract

About 30% of the ovulation induction cycles in GIFT and FIVET programmes are cancelled due to an inadequate response of patients to gonadotropins and/or clomiphene citrate. GnRH agonist-gonadotropins and/or "pure" FSH combination has been successful in inducing ovulation in patients with a previous history of cycle cancellation and/or alterations in the menstrual cycles. In order to reduce the number of cycle cancellations and obtain more homogeneous oocytes, GnRH agonist-gonadotropins and/or "pure" FSH combination in all candidates for GIFT and FIVET has been recently hypothesised. The Authors report results obtained from GnRH agonist-"pure" FSH combination in 30 normally menstruating patients of the GIFT programme: in 93% of cases the harvested oocytes were preovulatory, in 27.6% of cycles and in 28.6% of the GIFTs respectively an ongoing pregnancy was obtained. While the results obtained must be considered preliminary, they nevertheless suggest that the use of a combination of GnRH-agonist "pure" FSH in all patients in the GIFT programme may be of real clinical validity.
19
159
165
Induction of ovulation for gamete intrafallopian transfer (GIFT) using a gonadotropin-releasing hormone agonist and "pure" FSH: results obtained in 30 normally menstruating women / LA SALA, Giovanni Battista; Cantarelli, M; Parolari, G; Dessanti, L; Dall'Asta, D; Torelli, Mg; Salvatore, V; Dotti, C; Cavalieri, S; Brai, L.. - In: ACTA EUROPAEA FERTILITATIS. - ISSN 0587-2421. - ELETTRONICO. - 19:(1988), pp. 159-165.
LA SALA, Giovanni Battista; Cantarelli, M; Parolari, G; Dessanti, L; Dall'Asta, D; Torelli, Mg; Salvatore, V; Dotti, C; Cavalieri, S; Brai, L.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/861496
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