Recent clinical and toxicological studies have investigated the mineralcorticoid-like and hypertensive effects of liquorice, and we therefore set out to identify the active component responsible for these effects. We conducted a 30-day comparative analysis of glycyrrhizin and 18 beta-glycyrrhetinic acid and found that the latter causes significant variations both in systolic blood pressure and in the excretion in the urine of Ca++. The effects were fully reversible on suspension of treatment.

Glycyrrhizin and 18 beta-glycyrrhetinic acid: a comparative study of the pharmacological effects induced in the rat after prolonged oral treatment / Rossi, T; Vampa, G; Benvenuti, Stefania; Pini, Luigi Alberto; Galatulas, I; Bossa, R; Castelli, M; Ruberto, Ai; Baggio, G.. - In: IN VIVO. - ISSN 0258-851X. - STAMPA. - 8:(1994), pp. 317-320.

Glycyrrhizin and 18 beta-glycyrrhetinic acid: a comparative study of the pharmacological effects induced in the rat after prolonged oral treatment.

BENVENUTI, Stefania;PINI, Luigi Alberto;
1994

Abstract

Recent clinical and toxicological studies have investigated the mineralcorticoid-like and hypertensive effects of liquorice, and we therefore set out to identify the active component responsible for these effects. We conducted a 30-day comparative analysis of glycyrrhizin and 18 beta-glycyrrhetinic acid and found that the latter causes significant variations both in systolic blood pressure and in the excretion in the urine of Ca++. The effects were fully reversible on suspension of treatment.
1994
8
317
320
Glycyrrhizin and 18 beta-glycyrrhetinic acid: a comparative study of the pharmacological effects induced in the rat after prolonged oral treatment / Rossi, T; Vampa, G; Benvenuti, Stefania; Pini, Luigi Alberto; Galatulas, I; Bossa, R; Castelli, M; Ruberto, Ai; Baggio, G.. - In: IN VIVO. - ISSN 0258-851X. - STAMPA. - 8:(1994), pp. 317-320.
Rossi, T; Vampa, G; Benvenuti, Stefania; Pini, Luigi Alberto; Galatulas, I; Bossa, R; Castelli, M; Ruberto, Ai; Baggio, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/846289
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