The presence of PDGF receptor-alpha- and -beta- and TGF-beta-receptor (type II)-like molecules on the plasma membranes of the immunocytes of the mollusc Mytilus galloprovincialis was demonstrated by an immunocytochemical procedure. Furthermore, the present study provides evidence that PDGF-AB and TGF-beta 1 provoke cell shape changes in immunocytes via interactions with the respective receptors and that these extracellular signals are transduced along the phosphoinositide signaling pathway.
PDGF and TGF-beta induce cell shape changes in invertebrate immunocytes via specific cell surface receptors / Kletsas, D; Sassi, D; Franchini, Antonella; Ottaviani, Enzo. - In: EUROPEAN JOURNAL OF CELL BIOLOGY. - ISSN 0171-9335. - STAMPA. - 75:(1998), pp. 362-366. [10.1016/S0171-9335(98)80069-1]
PDGF and TGF-beta induce cell shape changes in invertebrate immunocytes via specific cell surface receptors
FRANCHINI, Antonella;OTTAVIANI, Enzo
1998
Abstract
The presence of PDGF receptor-alpha- and -beta- and TGF-beta-receptor (type II)-like molecules on the plasma membranes of the immunocytes of the mollusc Mytilus galloprovincialis was demonstrated by an immunocytochemical procedure. Furthermore, the present study provides evidence that PDGF-AB and TGF-beta 1 provoke cell shape changes in immunocytes via interactions with the respective receptors and that these extracellular signals are transduced along the phosphoinositide signaling pathway.
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