The effect of FK33 824, a stable analogue of methionine-enkephalin, on aldosterone (A), plasma renin activity (PRA) and cortisol (F) secretion were studied in 4 normal subjects. A significantly increased while PRA was unaffected and F decreased afted the drug adrninistration. We suggest that enkephalins may play a role in the control of A secretion by a mechanism of action independent on angiotensin II and ACTH.
THE EFFECT OF AN ENKEPHALIN ANALOG ON ALDOSTERONE SECRETION IN NORMAL SUBJECTS / Sandro, Loche; Felice, Petraglia; Carlo, Pintor; Antonella, Faedda; Facchinetti, Fabio; Stefano, Balzano; Andrea R., Genazzani; Roberto, Corda. - In: NEUROENDOCRINOLOGY LETTERS. - ISSN 0172-780X. - STAMPA. - 6:(1985), pp. 313-317.
THE EFFECT OF AN ENKEPHALIN ANALOG ON ALDOSTERONE SECRETION IN NORMAL SUBJECTS
FACCHINETTI, Fabio;
1985
Abstract
The effect of FK33 824, a stable analogue of methionine-enkephalin, on aldosterone (A), plasma renin activity (PRA) and cortisol (F) secretion were studied in 4 normal subjects. A significantly increased while PRA was unaffected and F decreased afted the drug adrninistration. We suggest that enkephalins may play a role in the control of A secretion by a mechanism of action independent on angiotensin II and ACTH.Pubblicazioni consigliate
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