The achievement of a pathologic complete response (pCR) in breast cancer patients treated with primary chemotherapy is the most reliable predictor of survival. Patients with hormone receptor (HR) positive tumors hare less likely to achieve a pCR; however, the prognostic role of pCR in these patients is not well characterized. In this study including 1731 patients, we have demonstrated that the achievement of pCR is associated with better outcome regardless of HR status.
Prognostic value of pathologic complete response after primary chemotherapy in patients with hormone receptor-positive breast cancer / Guarneri, Valentina; K., Broglio; S., Kau; M., Cristofanilli; Au, Buzdar; V., Valero; T., Buchholz; F., Meric; L., Middleton; Gn, Hortobagyi; AM Gonzalez, Angulo. - In: BREAST CANCER RESEARCH AND TREATMENT. - ISSN 0167-6806. - STAMPA. - 94, s1:(2005), pp. s127-s128. (Intervento presentato al convegno 28th San Antonio Breast Cancer Symposium tenutosi a San Antonio, TX nel December 8-12, 2005).
Prognostic value of pathologic complete response after primary chemotherapy in patients with hormone receptor-positive breast cancer.
GUARNERI, Valentina;
2005
Abstract
The achievement of a pathologic complete response (pCR) in breast cancer patients treated with primary chemotherapy is the most reliable predictor of survival. Patients with hormone receptor (HR) positive tumors hare less likely to achieve a pCR; however, the prognostic role of pCR in these patients is not well characterized. In this study including 1731 patients, we have demonstrated that the achievement of pCR is associated with better outcome regardless of HR status.Pubblicazioni consigliate
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