The aim of this study is to make an evaluation of the activity of endogenous opioid tonus in patients affected by menstrual migraine. We tested the LH response to naloxone injection, an opiate receptor antagonist, in 18 migraineurs in the early and late luteal periods going towards the attacks. The lack of any response in the latter group demonstrates an opioid disregulation in this kind of pathology.
Evaluation of central opioid tonus in menstrual migraine / F., Petraglia; E., Martignoni; D., Sola; C., Cicoli; Facchinetti, Fabio; G., Nappi; A. R., Genazzani. - In: CEPHALALGIA. - ISSN 0333-1024. - STAMPA. - 3 Suppl 1:(1983), pp. 98-100.
Evaluation of central opioid tonus in menstrual migraine.
FACCHINETTI, Fabio;
1983
Abstract
The aim of this study is to make an evaluation of the activity of endogenous opioid tonus in patients affected by menstrual migraine. We tested the LH response to naloxone injection, an opiate receptor antagonist, in 18 migraineurs in the early and late luteal periods going towards the attacks. The lack of any response in the latter group demonstrates an opioid disregulation in this kind of pathology.
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