The effects of transcutaneous electrical nerve stimulation on plasma and cerebrospinal fluid (CSF) levels of beta-Endorphin (beta-EP) were studied in 6 groups of pain-free patients. Different modes of TENS were applied for 20 minutes. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Plasma and CSF responses were not correlated suggesting that TENS activates different opiatergic pathways at central and peripheral level.
Central and peripheral beta-endorphin response to transcutaneous electrical nerve stimulation / Facchinetti, Fabio; G., Sforza; M., Amidei; C., Cozza; F., Petraglia; C., Montanari; A. R., Genazzani. - STAMPA. - 75:(1986), pp. 555-558.
Central and peripheral beta-endorphin response to transcutaneous electrical nerve stimulation.
FACCHINETTI, Fabio;
1986
Abstract
The effects of transcutaneous electrical nerve stimulation on plasma and cerebrospinal fluid (CSF) levels of beta-Endorphin (beta-EP) were studied in 6 groups of pain-free patients. Different modes of TENS were applied for 20 minutes. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Plasma and CSF responses were not correlated suggesting that TENS activates different opiatergic pathways at central and peripheral level.
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